The University of Chicago Header Logo

Connection

Jeffrey Rathmell to Signal Transduction

Back to Details
This is a "connection" page, showing publications Jeffrey Rathmell has written about Signal Transduction.
Jeffrey Rathmell
Connection Strength
2.670
Signal Transduction
  1. HIF-2a expression and metabolic signaling require ACSS2 in clear cell renal cell carcinoma. J Clin Invest. 2024 Jun 17; 134(12).
    View in: PubMed
    Score: 0.418
  2. Editorial overview: Metabolism of T cells: integrating nutrients, signals, and cell fate. Curr Opin Immunol. 2017 06; 46:viii-xi.
    View in: PubMed
    Score: 0.258
  3. Suppression of Glut1 and Glucose Metabolism by Decreased Akt/mTORC1 Signaling Drives T Cell Impairment in B Cell Leukemia. J Immunol. 2016 09 15; 197(6):2532-40.
    View in: PubMed
    Score: 0.242
  4. TGF-beta: a new role for an old AktTOR. Dev Cell. 2009 Jul; 17(1):6-8.
    View in: PubMed
    Score: 0.148
  5. Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways. J Immunol. 2008 Apr 01; 180(7):4476-86.
    View in: PubMed
    Score: 0.136
  6. Nutrient inputs and social metabolic control of T cell fate. Cell Metab. 2024 01 02; 36(1):10-20.
    View in: PubMed
    Score: 0.101
  7. Pathways of apoptosis in lymphocyte development, homeostasis, and disease. Cell. 2002 Apr; 109 Suppl:S97-107.
    View in: PubMed
    Score: 0.090
  8. MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function. Immunity. 2022 01 11; 55(1):65-81.e9.
    View in: PubMed
    Score: 0.087
  9. Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8+ T cells during the primary immune response. Immunity. 2021 04 13; 54(4):829-844.e5.
    View in: PubMed
    Score: 0.083
  10. Dysfunctional T cell metabolism in the tumor microenvironment. Cytokine Growth Factor Rev. 2017 Jun; 35:7-14.
    View in: PubMed
    Score: 0.064
  11. Metabolic Signaling Drives IFN-?. Cell Metab. 2016 11 08; 24(5):651-652.
    View in: PubMed
    Score: 0.062
  12. Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression. Nat Immunol. 2016 Dec; 17(12):1459-1466.
    View in: PubMed
    Score: 0.061
  13. Nutrients and the microenvironment to feed a T cell army. Semin Immunol. 2016 10; 28(5):505-513.
    View in: PubMed
    Score: 0.061
  14. mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation. Immunity. 2016 09 20; 45(3):540-554.
    View in: PubMed
    Score: 0.061
  15. Fluorescence-based measurement of cystine uptake through xCT shows requirement for ROS detoxification in activated lymphocytes. J Immunol Methods. 2016 11; 438:51-58.
    View in: PubMed
    Score: 0.061
  16. AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival. Cell Metab. 2016 Apr 12; 23(4):649-62.
    View in: PubMed
    Score: 0.059
  17. Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways. Nat Immunol. 2013 Jun; 14(6):611-8.
    View in: PubMed
    Score: 0.048
  18. Matched and mismatched metabolic fuels in lymphocyte function. Semin Immunol. 2012 Dec; 24(6):405-13.
    View in: PubMed
    Score: 0.047
  19. Dysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphoma. Proc Natl Acad Sci U S A. 2012 Jul 17; 109(29):11818-23.
    View in: PubMed
    Score: 0.046
  20. IL-7 is essential for homeostatic control of T cell metabolism in vivo. J Immunol. 2010 Apr 01; 184(7):3461-9.
    View in: PubMed
    Score: 0.039
  21. Methed-up FOXOs can't in-Akt-ivate. Mol Cell. 2008 Oct 24; 32(2):160-2.
    View in: PubMed
    Score: 0.035
  22. Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1. Mol Cell Biol. 2007 Jun; 27(12):4328-39.
    View in: PubMed
    Score: 0.032
  23. Metabolic regulation of Akt: roles reversed. J Cell Biol. 2006 Dec 18; 175(6):845-7.
    View in: PubMed
    Score: 0.031
  24. Lymphocyte selection by starvation: glucose metabolism and cell death. Trends Immunol. 2006 Jan; 27(1):4-7.
    View in: PubMed
    Score: 0.029
  25. Androgen signaling restricts glutaminolysis to drive sex-specific Th17 metabolism in allergic airway inflammation. J Clin Invest. 2024 Oct 15; 134(23).
    View in: PubMed
    Score: 0.027
  26. Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells. J Immunol. 2004 May 01; 172(9):5287-96.
    View in: PubMed
    Score: 0.026
  27. B-cell homeostasis: digital survival or analog growth? Immunol Rev. 2004 Feb; 197:116-28.
    View in: PubMed
    Score: 0.025
  28. Protein kinase C delta regulates mononuclear phagocytes and hinders response to immunotherapy in cancer. Sci Adv. 2023 12 22; 9(51):eadd3231.
    View in: PubMed
    Score: 0.025
  29. Hedgehog Signaling Regulates Treg to Th17 Conversion Through Metabolic Rewiring in Breast Cancer. Cancer Immunol Res. 2023 05 03; 11(5):687-702.
    View in: PubMed
    Score: 0.024
  30. The CD28 signaling pathway regulates glucose metabolism. Immunity. 2002 Jun; 16(6):769-77.
    View in: PubMed
    Score: 0.023
  31. Retinoic acid signaling acts as a rheostat to balance Treg function. Cell Mol Immunol. 2022 07; 19(7):820-833.
    View in: PubMed
    Score: 0.023
  32. CD4 T cells differentially express cellular machinery for serotonin signaling, synthesis, and metabolism. Int Immunopharmacol. 2020 Nov; 88:106922.
    View in: PubMed
    Score: 0.020
  33. ERa Signaling Increased IL-17A Production in Th17 Cells by Upregulating IL-23R Expression, Mitochondrial Respiration, and Proliferation. Front Immunol. 2019; 10:2740.
    View in: PubMed
    Score: 0.019
  34. Asymmetric PI3K Activity in Lymphocytes Organized by a PI3K-Mediated Polarity Pathway. Cell Rep. 2018 01 23; 22(4):860-868.
    View in: PubMed
    Score: 0.017
  35. Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models. Nat Med. 2018 02; 24(2):194-202.
    View in: PubMed
    Score: 0.017
  36. Anabolism-Associated Mitochondrial Stasis Driving Lymphocyte Differentiation over Self-Renewal. Cell Rep. 2016 12 20; 17(12):3142-3152.
    View in: PubMed
    Score: 0.016
  37. Metabolic stress is a barrier to Epstein-Barr virus-mediated B-cell immortalization. Proc Natl Acad Sci U S A. 2016 Feb 09; 113(6):E782-90.
    View in: PubMed
    Score: 0.015
  38. Designing a broad-spectrum integrative approach for cancer prevention and treatment. Semin Cancer Biol. 2015 Dec; 35 Suppl:S276-S304.
    View in: PubMed
    Score: 0.014
  39. Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses. Cell. 2015 Sep 10; 162(6):1217-28.
    View in: PubMed
    Score: 0.014
  40. Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability. Nat Immunol. 2015 Feb; 16(2):188-96.
    View in: PubMed
    Score: 0.014
  41. The liver kinase B1 is a central regulator of T cell development, activation, and metabolism. J Immunol. 2011 Oct 15; 187(8):4187-98.
    View in: PubMed
    Score: 0.011
  42. ER stress modulates cellular metabolism. Biochem J. 2011 Apr 01; 435(1):285-96.
    View in: PubMed
    Score: 0.010
  43. The c-Jun NH2-terminal kinase 2 plays a dominant role in human epidermal neoplasia. Cancer Res. 2010 Apr 15; 70(8):3080-8.
    View in: PubMed
    Score: 0.010
  44. Akt1 and Akt2 promote peripheral B-cell maturation and survival. Blood. 2010 May 20; 115(20):4043-50.
    View in: PubMed
    Score: 0.010
  45. Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2. Cell. 2005 Oct 07; 123(1):89-103.
    View in: PubMed
    Score: 0.007
  46. Homeostatic control of lymphocyte survival: potential origins and implications. Nat Immunol. 2002 Jun; 3(6):515-21.
    View in: PubMed
    Score: 0.006
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.