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Recognition of guanosine by dissimilar tRNA methyltransferases.
Academic Article
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tRNA Methyltransferases
Concept
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Mutations in MetG (methionyl-tRNA synthetase) and TrmD [tRNA (guanine-N1)-methyltransferase] conferring meropenem tolerance in Burkholderia thailandensis.
Academic Article
Why?
The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA.
Academic Article
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The expression of TRMT2A, a novel cell cycle regulated protein, identifies a subset of breast cancer patients with HER2 over-expression that are at an increased risk of recurrence.
Academic Article
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The Role of RNA Modifications and RNA-modifying Proteins in Cancer Therapy and Drug Resistance.
Academic Article
Why?
Kim, Hee-Jong
Person
Why?
A role for tRNA modifications in genome structure and codon usage.
Academic Article
Why?
Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.
Academic Article
Why?
METTL14 is a chromatin regulator independent of its RNA N6-methyladenosine methyltransferase activity.
Academic Article
Why?
RNA epigenetics.
Academic Article
Why?
He, Chuan
Person
Why?
Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.
Academic Article
Why?
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer.
Academic Article
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Preparation of Human Nuclear RNA m6A Methyltransferases and Demethylases and Biochemical Characterization of Their Catalytic Activity.
Academic Article
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