"tRNA Methyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the S-adenosyl-L-methionine-dependent methylation of ribonucleotide bases within a transfer RNA molecule. EC 2.1.1.
| Descriptor ID |
D012359
|
| MeSH Number(s) |
D08.811.913.555.500.925
|
| Concept/Terms |
tRNA Methyltransferases- tRNA Methyltransferases
- Methyltransferases, tRNA
- T RNA Methyltransferases
- Methyltransferases, T RNA
- RNA Methyltransferases, T
- RNA Methylases
- Methylases, RNA
- RNA, Transfer, Methyltransferases
|
Below are MeSH descriptors whose meaning is more general than "tRNA Methyltransferases".
Below are MeSH descriptors whose meaning is more specific than "tRNA Methyltransferases".
This graph shows the total number of publications written about "tRNA Methyltransferases" by people in this website by year, and whether "tRNA Methyltransferases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 2 | 3 |
| 2016 | 0 | 2 | 2 |
| 2018 | 1 | 0 | 1 |
| 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "tRNA Methyltransferases" by people in Profiles.
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Modifications in the T arm of tRNA globally determine tRNA maturation, function, and cellular fitness. Proc Natl Acad Sci U S A. 2024 Jun 25; 121(26):e2401154121.
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Chemical manipulation of m1A mediates its detection in human tRNA. RNA. 2024 Apr 16; 30(5):548-559.
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Mutations in MetG (methionyl-tRNA synthetase) and TrmD [tRNA (guanine-N1)-methyltransferase] conferring meropenem tolerance in Burkholderia thailandensis. J Antimicrob Chemother. 2018 02 01; 73(2):332-338.
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Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer. Nat Commun. 2016 04 27; 7:11375.
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Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms. Hum Mol Genet. 2016 05 15; 25(10):2070-2081.
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Recognition of guanosine by dissimilar tRNA methyltransferases. RNA. 2012 Sep; 18(9):1687-701.
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A role for tRNA modifications in genome structure and codon usage. Cell. 2012 Mar 30; 149(1):202-13.
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Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations. Nat Genet. 2012 Feb 19; 44(3):302-6.
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The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA. Angew Chem Int Ed Engl. 2010 Nov 15; 49(47):8885-8.
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The expression of TRMT2A, a novel cell cycle regulated protein, identifies a subset of breast cancer patients with HER2 over-expression that are at an increased risk of recurrence. BMC Cancer. 2010 Mar 22; 10:108.