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Godley, Lucy
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Item TypeName
Concept Dioxygenases
Academic Article Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.
Academic Article Gene mutations, epigenetic dysregulation, and personalized therapy in myeloid neoplasia: are we there yet?
Academic Article Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors.
Academic Article TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis.
Academic Article Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
Academic Article Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia.
Academic Article Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis.
Academic Article Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.
Academic Article DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
Academic Article TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor-Binding Sites in Chronic Myelomonocytic Leukemia.
Academic Article 5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy.
Academic Article Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes.
Academic Article Identifying Inherited and Acquired Genetic Factors Involved in Poor Stem Cell Mobilization and Donor-Derived Malignancy.
Academic Article Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.
Academic Article Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis.
Academic Article HIF-1 directly induces TET3 expression to enhance 5-hmC density and induce erythroid gene expression in hypoxia.
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  • Dioxygenases