"Dioxygenases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-heme iron-containing enzymes that incorporate two atoms of OXYGEN into the substrate. They are important in biosynthesis of FLAVONOIDS; GIBBERELLINS; and HYOSCYAMINE; and for degradation of AROMATIC HYDROCARBONS.
| Descriptor ID |
D049308
|
| MeSH Number(s) |
D08.811.682.690.416
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Dioxygenases".
Below are MeSH descriptors whose meaning is more specific than "Dioxygenases".
This graph shows the total number of publications written about "Dioxygenases" by people in this website by year, and whether "Dioxygenases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 2 | 1 | 3 |
| 2011 | 0 | 5 | 5 |
| 2012 | 2 | 2 | 4 |
| 2013 | 1 | 1 | 2 |
| 2014 | 2 | 4 | 6 |
| 2015 | 1 | 6 | 7 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 2 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 3 | 3 |
| 2020 | 1 | 2 | 3 |
| 2021 | 2 | 0 | 2 |
| 2022 | 2 | 0 | 2 |
| 2024 | 2 | 1 | 3 |
| 2025 | 0 | 5 | 5 |
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Below are the most recent publications written about "Dioxygenases" by people in Profiles.
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Low-input proteomics identifies vWF as a negative regulator of Tet2 mutant hematopoietic stem cell expansion. Cell Rep. 2026 Jan 27; 45(1):116770.
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Chronic myelomonocytic leukemia in the young (aged 50 years and younger): Divergent clinical and molecular characteristics from the elderly. Cancer. 2025 Nov 15; 131(22):e70176.
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A myeloid Tet2-IL-1ß axis modulates intestinal inflammation by restricting catecholaminergic stimulation of enterochromaffin cell differentiation. Immunity. 2025 Nov 11; 58(11):2785-2798.e4.
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Tet Methylcytosine Dioxygenase 2 (TET2) Mutation Drives a Global Hypermethylation Signature in Patients With Pulmonary Arterial Hypertension (PAH): Correlation With Altered Gene Expression Relevant to a Common T Cell Phenotype. Compr Physiol. 2025 04; 15(2):e70011.
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TP53 mutations and TET2 deficiency cooperate to drive leukemogenesis and establish an immunosuppressive environment. J Clin Invest. 2025 May 15; 135(10).
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Genetic and environmental risks for clonal hematopoiesis and cancer. J Exp Med. 2025 01 06; 222(1).
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RNA m5C oxidation by TET2 regulates chromatin state and leukaemogenesis. Nature. 2024 10; 634(8035):986-994.
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Neutrophil-mediated innate immune resistance to bacterial pneumonia is dependent on Tet2 function. J Clin Invest. 2024 04 04; 134(11).
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PU.1-Dependent Enhancer Inhibition Separates Tet2-Deficient Hematopoiesis from Malignant Transformation. Blood Cancer Discov. 2022 09 06; 3(5):444-467.
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Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis. Cell Host Microbe. 2022 07 13; 30(7):1003-1019.e10.