| Item Type | Name |
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Concept
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Thyroxine-Binding Proteins
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Concept
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Thyroxine
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Concept
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Thyroxine-Binding Globulin
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Academic Article
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In vitro expression of thyroxine-binding globulin (TBG) variants. Impaired secretion of TBGPRO-227 but not TBGPRO-113.
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Academic Article
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Multiple genetic factors in the heterogeneity of thyroid hormone resistance.
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Academic Article
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Thyroid function tests and characterization of thyroxine-binding globulin in the carbohydrate-deficient glycoprotein syndrome type I.
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Academic Article
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Resistance to thyroid hormone caused by two mutant thyroid hormone receptors beta, R243Q and R243W, with marked impairment of function that cannot be explained by altered in vitro 3,5,3'-triiodothyroinine binding affinity.
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Academic Article
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A new family with hyperthyroxinemia caused by transthyretin Val109 misdiagnosed as thyrotoxicosis and resistance to thyroid hormone--a clinical research center study.
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Academic Article
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Thyroid dysfunction is not associated with alterations in serum leptin levels.
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Academic Article
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Thyroxine-binding globulin: organization of the gene and variants.
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Academic Article
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Thyrotropin regulation by thyroid hormone in thyroid hormone receptor beta-deficient mice.
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Academic Article
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Evaluation of pituitary and peripheral tissue markers of thyroid hormone action in an Iranian family with resistance to thyroid hormone.
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Academic Article
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An additional carbohydrate chain in the variant thyroxine-binding globulin-Gary (TBGAsn-96) impairs its secretion.
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Academic Article
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Selective pituitary resistance to thyroid hormone produced by expression of a mutant thyroid hormone receptor beta gene in the pituitary gland of transgenic mice.
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Academic Article
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Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone.
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Academic Article
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Thyroid hormone action on liver, heart, and energy expenditure in thyroid hormone receptor beta-deficient mice.
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Academic Article
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Familial dysalbuminemic hyperthyroxinemia in a Swiss family caused by a mutant albumin (R218P) shows an apparent discrepancy between serum concentration and affinity for thyroxine.
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Academic Article
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Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease.
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Academic Article
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Sequencing of the variant thyroxine-binding globulin (TBG)-San Diego reveals two nucleotide substitutions.
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Academic Article
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Identification of thyroxine-binding globulin-San Diego in a family from Houston and its characterization by in vitro expression using Xenopus oocytes.
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Academic Article
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Low serum free thyroxine index in ambulating elderly is due to a resetting of the threshold of thyrotropin feedback suppression.
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Academic Article
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Five new families with resistance to thyroid hormone not caused by mutations in the thyroid hormone receptor beta gene.
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Academic Article
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Complete thyroxine-binding globulin (TBG) deficiency produced by a mutation in acceptor splice site causing frameshift and early termination of translation (TBG-Kankakee).
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Academic Article
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Congenital hypothyroidism in a child with unsuspected familial dysalbuminemic hyperthyroxinemia caused by a mutation (R218H) in the human albumin gene.
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Academic Article
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Complete thyroxine-binding globulin (TBG) deficiency in two families without mutations in coding or promoter regions of the TBG genes: in vitro demonstration of exon skipping.
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Academic Article
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Characterization of T(4)-binding globulin cleaved by human leukocyte elastase.
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Academic Article
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Type 1 iodothyronine deiodinase in the house musk shrew (Suncus murinus, Insectivora: Soricidae): cloning and characterization of complementary DNA, unique tissue distribution and regulation by T(3).
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Academic Article
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Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency.
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Academic Article
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Low TSH requirement and goiter in transgenic mice overexpressing IGF-I and IGF-Ir receptor in the thyroid gland.
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Academic Article
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RXR receptor agonist suppression of thyroid function: central effects in the absence of thyroid hormone receptor.
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Academic Article
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Reduced nuclear triiodothyronine receptors in starvation-induced hypothyroidism.
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Academic Article
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Sequence of the variant thyroxine-binding globulin (TBG) in a Montreal family with partial TBG deficiency.
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Academic Article
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Sleep deprivation in the rat: XIII. The effect of hypothyroidism on sleep deprivation symptoms.
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Academic Article
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Partial thyroxine-binding globulin (TBG) deficiency in a family with no detectable mutation of the TBG gene.
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Academic Article
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Pseudomalabsorption of levothyroxine.
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Academic Article
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Partial deficiency of thyroxine-binding globulin-Allentown is due to a mutation in the signal peptide.
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Academic Article
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Three novel mutations causing complete T(4)-binding globulin deficiency.
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Academic Article
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Thyroid function and effect of aging in combined hetero/homozygous mice deficient in thyroid hormone receptors alpha and beta genes.
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Academic Article
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Characterization and primary structures of bovine and porcine thyroxine-binding globulin.
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Academic Article
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Complete thyroxine-binding globulin (TBG) deficiency caused by a single nucleotide deletion in the TBG gene.
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Academic Article
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Nuclear receptors for thyroid hormone.
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Academic Article
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Unique regulation of thyroid hormone metabolism during fasting in the house musk shrew (Suncus murinus, Insectivora: Soricidae).
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Academic Article
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Neonatal detection of generalized resistance to thyroid hormone.
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Academic Article
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Sequencing of the variant thyroxine-binding globulin (TBG)-Quebec reveals two nucleotide substitutions.
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Academic Article
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Replacement of Leu227 by Pro in thyroxine-binding globulin (TBG) is associated with complete TBG deficiency in three of eight families with this inherited defect.
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Academic Article
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Defective thyroglobulin storage in LDL receptor-associated protein-deficient mice.
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Academic Article
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Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity.
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Academic Article
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Molecular basis for the properties of the thyroxine-binding globulin-slow variant in American blacks.
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Academic Article
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Effect of total sleep deprivation on 5'-deiodinase activity of rat brown adipose tissue.
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Academic Article
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Sleep deprivation in the rat: V. Energy use and mediation.
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Academic Article
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Sleep deprivation in the rat: IX. Recovery.
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Academic Article
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A thyroid hormone analog with reduced dependence on the monocarboxylate transporter 8 for tissue transport.
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Academic Article
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A new inherited abnormality of thyroxine-binding globulin (TBG-San Diego) with decreased affinity for thyroxine and triiodothyronine.
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Academic Article
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A mutation causing reduced biological activity and stability of thyroxine-binding globulin probably as a result of abnormal glycosylation of the molecule.
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Academic Article
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Generalized resistance to thyroid hormone associated with a mutation in the ligand-binding domain of the human thyroid hormone receptor beta.
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Academic Article
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Mice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion.
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Academic Article
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Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice.
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Academic Article
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Thyroid hormone receptor a and regulation of type 3 deiodinase.
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Academic Article
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Selenium supplementation fails to correct the selenoprotein synthesis defect in subjects with SBP2 gene mutations.
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Academic Article
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Inherited thyroxine-binding globulin abnormalities in man.
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Academic Article
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Disruption of the melanin-concentrating hormone receptor 1 (MCH1R) affects thyroid function.
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Academic Article
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Role of type 2 deiodinase in response to acute lung injury (ALI) in mice.
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Academic Article
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Two new inherited defects of the thyroxine-binding globulin (TBG) molecule presenting as partial TBG deficiency.
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Academic Article
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Graves' disease associated with familial deficiency of thyroxine-binding globulin.
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Academic Article
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Effect of estrogen on the synthesis and secretion of thyroxine-binding globulin by a human hepatoma cell line, Hep G2.
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Academic Article
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Normal cellular uptake of thyroxine from serum of patients with familial dysalbuminemic hyperthyroxinemia or elevated thyroxine-binding globulin.
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Academic Article
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Characterization of thyroxine-binding globulin secreted by a human hepatoma cell line.
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Academic Article
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Isoelectric focusing variant thyroxine-binding globulin in American blacks: increased heat lability and reduced serum concentration.
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Academic Article
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X-chromosome-linked inheritance of the variant thyroxine-binding globulin in Australian aborigines.
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Academic Article
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The computer in the diagnosis of thyroid disease.
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Academic Article
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Studies of a sibship with apparent hereditary resistance to the intracellular action of thyroid hormone.
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Academic Article
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Elevated serum thyroglobulin level in congenital thyroxine-binding globulin deficiency.
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Academic Article
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Resistance to thyroid hormone in a patient with thyroid dysgenesis.
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Academic Article
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Transient elevation of serum thyroid hormone concentration after initiation of replacement therapy in myxedema.
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Academic Article
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Human thyroxine-binding globulin gene: complete sequence and transcriptional regulation.
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Academic Article
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Variant thyroxine-binding globulin in serum of Australian aborigines: a comparison with familial TBG deficiency in Caucasians and American blacks.
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Academic Article
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Sequence of the variant thyroxine-binding globulin of Australian aborigines. Only one of two amino acid replacements is responsible for its altered properties.
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Academic Article
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Mice deficient in dual oxidase maturation factors are severely hypothyroid.
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Academic Article
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Parameters of thyroid function in serum of 16 selected vertebrate species: a study of PBI, serum T4, free T4, and the pattern of T4 and T3 binding to serum proteins.
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Academic Article
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T3 thyrotoxicosis. Thyrotoxicosis due to elevated serum triiodothyronine levels.
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Academic Article
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The differential stimulatory effect of thyroid hormone on growth hormone synthesis and estrogen on prolactin synthesis due to accumulation of specific messenger ribonucleic acids.
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Academic Article
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Suppression of serum thyrotropin (TSH) by L-dopa in chronic hypothyroidism: interrelationships in the regulation of TSH and prolactin secretion.
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Academic Article
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Genetic polymorphism of rhesus thyroxine-binding prealbumin: evidence for tetrameric structure in primates.
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Academic Article
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Inherited X chromosome linked thyroxine-binding globulin (TBG) deficiency in a homozygous female.
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Academic Article
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Mosaicism of a thyroid hormone receptor-beta gene mutation in resistance to thyroid hormone.
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Academic Article
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Defective thyroid hormone feedback regulation in the syndrome of peripheral resistance to thyroid hormone.
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Academic Article
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The role of glycosylation in the molecular conformation and secretion of thyroxine-binding globulin.
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Academic Article
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Molecular and structural characterization of the heat-resistant thyroxine-binding globulin-Chicago.
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Academic Article
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Radioimmunoassay for serum triiodothyronine: evaluation of simple techniques to control interference from binding proteins.
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Academic Article
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Continuing occurrence of thyroid carcinoma after irradiation to the neck in infancy and childhood.
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Academic Article
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Alterations in thyroxine (T 4 ) and tri-iodothyronine (T 3 ) binding to serum proteins by heat.
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Academic Article
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Gene screening in Japanese families with complete deficiency of thyroxine-binding globulin demonstrates that a nucleotide deletion at codon 352 may be a race specific mutation.
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Academic Article
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Relationship of oligosaccharide modification to the cause of serum thyroxine-binding globulin excess.
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Academic Article
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Direct application of radioiodinated aminoacyl tRNA for radiolabeling nascent proteins.
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Academic Article
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Measurement of thyroxine uptake from serum by cultured human hepatocytes as an index of thyroid status: reduced thyroxine uptake from serum of patients with nonthyroidal illness.
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Academic Article
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Immunoreactive growth hormone in endemic cretins in Ecuador.
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Academic Article
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Chiari-Frommel syndrome in a patient with primary adrenocortical insufficiency.
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Academic Article
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Estimation of the T 4 binding capacity of serum TBG and TBPA by a single T 4 load ion exchange resin method.
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Academic Article
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Endemic goiter with hypothyroidism in three generations.
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Academic Article
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Familial syndrome combining deaf-mutism, stuppled epiphyses, goiter and abnormally high PBI: possible target organ refractoriness to thyroid hormone.
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Academic Article
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Familial thyroxine-binding globulin deficiency in a patient with Turner's syndrome (XO). Genetic study of a kindred.
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Academic Article
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TBG deficiency: description of two novel mutations associated with complete TBG deficiency and review of the literature.
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Academic Article
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Thyroid function in a uremic rat model. Evidence suggesting tissue hypothyroidism.
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Academic Article
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Bidirectional thyroxine exchange in pregnant sheep.
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Academic Article
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Metabolism of L-thyroxine (T4) and L-triiodothyronine (T3) by human fibroblasts in tissue culture: evidence for cellular binding proteins and conversion of T4 to T3.
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Academic Article
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Modulation of thyroglobulin messenger RNA accumulation in the rat thyroid.
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Academic Article
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High prevalence of thyroxine-binding globulin deficiency among Bedouin infants in southern Israel.
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Academic Article
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Hormonal regulation of glycosaminoglycan accumulation in fibroblasts from patients with resistance to thyroid hormone.
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Academic Article
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Thyroid dysfunction in chronic renal failure. A study of the pituitary-thyroid axis and peripheral turnover kinetics of thyroxine and triiodothyronine.
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Academic Article
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Diurnal rhythm in total serum thyroxine levels.
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Academic Article
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Common tests of thyroid function in serum.
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Academic Article
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Pituitary-thyroid setpoint and thyrotropin receptor expression in consomic rats.
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Academic Article
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Sleep deprivation in the rat: XIX. Effects of thyroxine administration.
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Academic Article
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Molecular basis of inherited thyroxine-binding globulin defects.
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Academic Article
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Thyroid hormone relationships between maternal and fetal circulations in human pregnancy at term: a study in patients with normal and abnormal thyroid function.
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Academic Article
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Radioimmunoassays specific for the tertiary and primary structures of thyroxine-binding globulin (TBG): measurement of denatured TBG in serum.
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Academic Article
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The influence of percutaneous fine needle aspiration on serum thyroglobulin.
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Academic Article
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Linkage of familial dysalbuminemic hyperthyroxinemia to the albumin gene in a large Amish kindred.
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Academic Article
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An identical missense mutation in the albumin gene results in familial dysalbuminemic hyperthyroxinemia in 8 unrelated families.
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Academic Article
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In vivo interaction of steroid receptor coactivator (SRC)-1 and the activation function-2 domain of the thyroid hormone receptor (TR) beta in TRbeta E457A knock-in and SRC-1 knockout mice.
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Academic Article
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Approach to the patient with resistance to thyroid hormone and pregnancy.
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Academic Article
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Nuclear thyroid hormone receptors in cultured human fibroblasts: improved method of isolation, partial characterization, and interaction with chromatin.
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Academic Article
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Inherited abnormality of thyroxine-binding globulin with no demonstrable thyroxine-binding activity and high serum levels of denatured thyroxine-binding globulin.
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Academic Article
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Homogeneous apoenzyme reactivation immunoassay for thyroxin-binding globulin in serum.
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Academic Article
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Variant thyroxine-binding globulin in serum of Australian aborigines: its physical, chemical and biological properties.
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Academic Article
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Thyrotropin controls transcription of the thyroglobulin gene.
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Academic Article
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The consequences of inappropriate treatment because of failure to recognize the syndrome of pituitary and peripheral tissue resistance to thyroid hormone.
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Academic Article
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Complete deficiency of thyroxine-binding globulin (TBG-CD Buffalo) caused by a new nonsense mutation in the thyroxine-binding globulin gene.
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Academic Article
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Familial dysalbuminemic hypertriiodothyroninemia: a new, dominantly inherited albumin defect.
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Academic Article
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Genetic analysis reveals different functions for the products of the thyroid hormone receptor alpha locus.
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Academic Article
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Molecular cloning and primary structure of rat thyroxine-binding globulin.
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Academic Article
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Serum thyrotropin and prolactin in the syndrome of generalized resistance to thyroid hormone: responses to thyrotropin-releasing hormone stimulation and short term triiodothyronine suppression.
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Academic Article
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Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice.
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Academic Article
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Thyroid hormone receptor beta gene mutation (P453A) in a family producing resistance to thyroid hormone.
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Academic Article
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Metabolism of thyroxine-binding globulin in man. Abnormal rate of synthesis in inherited thyroxine-binding globulin deficiency and excess.
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Academic Article
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The action of thyroid hormone.
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Academic Article
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Thyroid hormone-regulated mouse cerebral cortex genes are differentially dependent on the source of the hormone: a study in monocarboxylate transporter-8- and deiodinase-2-deficient mice.
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Academic Article
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Leukocyte alkaline phosphatase in hypothyroidism and hyperthyroidism. Response to initiation of thyroxine replacement therapy.
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Academic Article
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Detection of the thyroxine-binding globulin (TBG) gene in six unrelated families with complete TBG deficiency.
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Academic Article
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Generation of functional thyroid from embryonic stem cells.
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Academic Article
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Inherited heat-stable variant thyroxine-binding globulin (TBG-Chicago).
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Academic Article
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Reduced affinity for thyroxine in two of three structural thyroxine-binding prealbumin variants associated with familial amyloidotic polyneuropathy.
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Academic Article
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Reduced clearance rate of thyroxine-binding globulin (TBG) with increased sialylation: a mechanism for estrogen-induced elevation of serum TBG concentration.
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Academic Article
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A study on the inheritance of thyroxine-binding globulin (TBG) deficiency from data obtained in 13 families detected by a neonatal screening program.
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Academic Article
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Study of four new kindreds with inherited thyroxine-binding globulin abnormalities. Possible mutations of a single gene locus.
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Academic Article
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Neonatal hypothyroidism and goiter in one infant of each of two sets of twins due to maternal therapy with antithyroid drugs.
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Academic Article
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Abnormal thyroxine metabolism in hyposomatotrophic dwarfism and inhibition of responsiveness to TRH during GH therapy.
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Academic Article
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Parameters of thyroid function in maternal and cord serum at term pregnancy.
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Academic Article
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Studies on human thyroxine-binding globulin (TBG). IX. Some physical, chemical, and biological properties of radioiodinated TBG and partially desialylated TBG.
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Academic Article
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Reduced triiodothyronine content in liver but not pituitary of the uremic rat model: demonstration of changes compatible with thyroid hormone deficiency in liver only.
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Academic Article
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Growth hormone responses to thyroid hormone in the neonatal rat: resistance and anamnestic response.
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Academic Article
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Do clinical manifestations of resistance to thyroid hormone correlate with the functional alteration of the corresponding mutant thyroid hormone-beta receptors?
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Academic Article
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Coexistence of THRB and TBG gene mutations in a Turkish family.
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Academic Article
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Changes in thyroid status during perinatal development of MCT8-deficient male mice.
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Academic Article
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A novel mechanism of inherited TBG deficiency: mutation in a liver-specific enhancer.
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Academic Article
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Placenta passage of the thyroid hormone analog DITPA to male wild-type and Mct8-deficient mice.
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Academic Article
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A novel mutation in the Albumin gene (R218S) causing familial dysalbuminemic hyperthyroxinemia in a family of Bangladeshi extraction.
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Academic Article
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A TSHß Variant with Impaired Immunoreactivity but Intact Biological Activity and Its Clinical Implications.
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Academic Article
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Inherited defects of thyroxine-binding proteins.
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Academic Article
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Desensitization and Incomplete Recovery of Hepatic Target Genes After Chronic Thyroid Hormone Treatment and Withdrawal in Male Adult Mice.
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Academic Article
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Overexpression of Interleukin-4 in the Thyroid of Transgenic Mice Upregulates the Expression of Duox1 and the Anion Transporter Pendrin.
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Academic Article
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Oncogene-induced senescence and its evasion in a mouse model of thyroid neoplasia.
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Academic Article
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A Novel Mutation in the TBG Gene Producing Partial Thyroxine-Binding Globulin Deficiency (Glencoe) Identified in 2 Families.
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Academic Article
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Homozygous Mutation in Human Serum Albumin and Its Implication on Thyroid Tests.
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Academic Article
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Very Severe Resistance to Thyroid Hormone ß in One of Three Affected Members of a Family with a Novel Mutation in the THRB Gene.
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Academic Article
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Intracerebroventricular administration of the thyroid hormone analog TRIAC increases its brain content in the absence of MCT8.
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Academic Article
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Free Thyroxine Concentrations in Sera of Individuals with Familial Dysalbuminemic Hyperthyroxinemia: A Comparison of Three Methods of Measurement.
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Academic Article
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Insertion of an Alu Element in Thyroglobulin Gene as a Novel Cause of Congenital Hypothyroidism.
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Academic Article
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Prenatal Treatment of Thyroid Hormone Cell Membrane Transport Defect Caused by MCT8 Gene Mutation.
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Academic Article
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Early Diagnosis and Treatment of an Infant with a Novel Thyroid Hormone Receptor a Gene (pC380SfsX9) Mutation.
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Academic Article
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Novel DIO1 Gene Mutation Acting as Phenotype Modifier for Novel Compound Heterozygous TPO Gene Mutations Causing Congenital Hypothyroidism.
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Academic Article
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XB130 Deficiency Causes Congenital Hypothyroidism in Mice due to Disorganized Apical Membrane Structure and Function of Thyrocytes.
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Academic Article
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Severe Resistance to Thyroid Hormone Beta in a Patient with Athyreosis.
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Academic Article
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Foxe1 Deletion in the Adult Mouse Is Associated With Increased Thyroidal Mast Cells and Hypothyroidism.
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Academic Article
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Iodotyrosines Are Biomarkers for Preclinical Stages of Iodine-Deficient Hypothyroidism in Dehal1-Knockout Mice.
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Grant
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STUDIES ON REGULATION AND MECHANISM OF HORMONE ACTION
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