| Item Type | Name |
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Concept
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Growth Inhibitors
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Concept
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Fibroblast Growth Factors
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Concept
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Insulin-Like Growth Factor I
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Concept
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Endothelial Growth Factors
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Concept
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Hepatocyte Growth Factor
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Concept
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Transforming Growth Factor beta
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Concept
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Hematopoietic Cell Growth Factors
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Concept
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Receptors, Fibroblast Growth Factor
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Concept
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Receptors, Growth Factor
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Concept
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Vascular Endothelial Growth Factor Receptor-2
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Concept
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Vascular Endothelial Growth Factors
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Concept
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Cell Growth Processes
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Concept
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Receptors, Vascular Endothelial Growth Factor
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Concept
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Vascular Endothelial Growth Factor A
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Concept
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Epidermal Growth Factor
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Concept
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Growth Substances
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Concept
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Vascular Endothelial Growth Factor Receptor-1
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Academic Article
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Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL.
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Academic Article
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The phosphatidylinositol polyphosphate 5-phosphatase SHIP and the protein tyrosine phosphatase SHP-2 form a complex in hematopoietic cells which can be regulated by BCR/ABL and growth factors.
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Academic Article
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Hematopoietic growth factors signal through the formation of reactive oxygen species.
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Academic Article
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Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571.
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Academic Article
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Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells.
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Academic Article
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Vascular endothelial growth factor-induced migration of multiple myeloma cells is associated with beta 1 integrin- and phosphatidylinositol 3-kinase-dependent PKC alpha activation.
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Academic Article
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Role of the cytoskeletal protein paxillin in oncogenesis.
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Academic Article
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Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition.
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Academic Article
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Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer.
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Academic Article
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Activated c-Met signals through PI3K with dramatic effects on cytoskeletal functions in small cell lung cancer.
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Academic Article
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c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention.
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Academic Article
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Activation of HGF/c-Met pathway contributes to the reactive oxygen species generation and motility of small cell lung cancer cells.
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Academic Article
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A selective small molecule inhibitor of c-Met, PHA665752, inhibits tumorigenicity and angiogenesis in mouse lung cancer xenografts.
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Academic Article
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Epidermal growth factor receptor mutations and susceptibility to targeted therapy in lung cancer.
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Academic Article
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Epidermal growth factor receptor - mediated signal transduction in the development and therapy of gliomas.
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Academic Article
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c-Met: structure, functions and potential for therapeutic inhibition.
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Academic Article
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c-Met and hepatocyte growth factor: potential as novel targets in cancer therapy.
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Academic Article
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Efficacy and safety of bevacizumab plus erlotinib for patients with recurrent ovarian, primary peritoneal, and fallopian tube cancer: a trial of the Chicago, PMH, and California Phase II Consortia.
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Academic Article
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The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma.
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Academic Article
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Lymphatic vessel density is not associated with lymph node metastasis in non-small cell lung carcinoma.
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Academic Article
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The role of ephrins and Eph receptors in cancer.
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Academic Article
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Expression and mutational analysis of MET in human solid cancers.
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Academic Article
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MET pathway as a therapeutic target.
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Academic Article
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Functional analysis of c-Met/hepatocyte growth factor pathway in malignant pleural mesothelioma.
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Academic Article
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PAX6 is expressed in pancreatic cancer and actively participates in cancer progression through activation of the MET tyrosine kinase receptor gene.
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Academic Article
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CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinases.
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Academic Article
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c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion.
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Academic Article
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Rapid and dramatic radiographic and clinical response to an ALK inhibitor (crizotinib, PF02341066) in an ALK translocation-positive patient with non-small cell lung cancer.
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Academic Article
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Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC delta and E-cadherin.
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Academic Article
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Fyn is downstream of the HGF/MET signaling axis and affects cellular shape and tropism in PC3 cells.
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Academic Article
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Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion.
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Academic Article
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Effect of a c-Met-specific, ATP-competitive small-molecule inhibitor SU11274 on human ovarian carcinoma cell growth, motility, and invasion.
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Academic Article
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Inhibition of MET receptor tyrosine kinase and its ligand hepatocyte growth factor.
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Academic Article
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Overexpression of the µ-opioid receptor in human non-small cell lung cancer promotes Akt and mTOR activation, tumor growth, and metastasis.
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Academic Article
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Melanoma proteoglycan modifies gene expression to stimulate tumor cell motility, growth, and epithelial-to-mesenchymal transition.
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Academic Article
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MET, HGF, EGFR, and PXN gene copy number in lung cancer using DNA extracts from FFPE archival samples and prognostic significance.
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Academic Article
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MET and phosphorylated MET as potential biomarkers in lung cancer.
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Academic Article
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Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer.
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Academic Article
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Role of protein kinase C ß and vascular endothelial growth factor receptor in malignant pleural mesothelioma: Therapeutic implications and the usefulness of Caenorhabditis elegans model organism.
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Academic Article
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Inhibition of MET receptor tyrosine kinase and its ligand hepatocyte growth factor.
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Academic Article
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c-Met is a potentially new therapeutic target for treatment of human melanoma.
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Academic Article
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Shc phosphorylation in myeloid cells is regulated by granulocyte macrophage colony-stimulating factor, interleukin-3, and steel factor and is constitutively increased by p210BCR/ABL.
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Academic Article
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Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion.
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Academic Article
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Novel oncogenic mutations of CBL in human acute myeloid leukemia that activate growth and survival pathways depend on increased metabolism.
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Academic Article
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NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases.
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Academic Article
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Personalized treatment of lung cancer.
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Academic Article
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Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer.
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Academic Article
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Prognostic significance of angiogenesis and angiogenic growth factors in nonsmall cell lung cancer.
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Academic Article
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Inhibition of epidermal growth factor receptor signaling in malignant pleural mesothelioma.
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Academic Article
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Molecular and cellular biology of small cell lung cancer.
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Academic Article
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Haptoglobin alpha-subunit and hepatocyte growth factor can potentially serve as serum tumor biomarkers in small cell lung cancer.
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Academic Article
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CD44 regulates hepatocyte growth factor-mediated vascular integrity. Role of c-Met, Tiam1/Rac1, dynamin 2, and cortactin.
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Academic Article
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Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity.
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Academic Article
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RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma.
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Academic Article
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Activity of crizotinib (PF02341066), a dual mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK) inhibitor, in a non-small cell lung cancer patient with de novo MET amplification.
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Academic Article
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Role of MetMAb (OA-5D5) in c-MET active lung malignancies.
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Academic Article
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Durable complete response of metastatic gastric cancer with anti-Met therapy followed by resistance at recurrence.
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Academic Article
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The EphB4 receptor tyrosine kinase promotes lung cancer growth: a potential novel therapeutic target.
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Academic Article
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MET as a possible target for non-small-cell lung cancer.
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Academic Article
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Critical role of S1PR1 and integrin ß4 in HGF/c-Met-mediated increases in vascular integrity.
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Academic Article
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The Mu opioid receptor promotes opioid and growth factor-induced proliferation, migration and Epithelial Mesenchymal Transition (EMT) in human lung cancer.
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Academic Article
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Role of c-Met/phosphatidylinositol 3-kinase (PI3k)/Akt signaling in hepatocyte growth factor (HGF)-mediated lamellipodia formation, reactive oxygen species (ROS) generation, and motility of lung endothelial cells.
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Academic Article
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Expression of the EPHB4 receptor tyrosine kinase in head and neck and renal malignancies--implications for solid tumors and potential for therapeutic inhibition.
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Academic Article
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Role of PAX8 in the regulation of MET and RON receptor tyrosine kinases in non-small cell lung cancer.
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Academic Article
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Non-small cell lung cancer is susceptible to induction of DNA damage responses and inhibition of angiogenesis by telomere overhang oligonucleotides.
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Academic Article
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Multiple Endocrine Disruption by the MET/ALK Inhibitor Crizotinib in Patients With Non-small Cell Lung Cancer.
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Academic Article
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Combined MET inhibition and topoisomerase I inhibition block cell growth of small cell lung cancer.
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Academic Article
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Fibroblast growth factor signaling and inhibition in non-small cell lung cancer and their role in squamous cell tumors.
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Academic Article
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AXL mediates resistance to cetuximab therapy.
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Academic Article
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Nuclear epidermal growth factor receptor is a functional molecular target in triple-negative breast cancer.
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Academic Article
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Role played by paxillin and paxillin tyrosine phosphorylation in hepatocyte growth factor/sphingosine-1-phosphate-mediated reactive oxygen species generation, lamellipodia formation, and endothelial barrier function.
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Academic Article
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Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer.
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Academic Article
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Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.
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Academic Article
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RETRACTED: The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor.
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Academic Article
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TOPK (T-LAK cell-originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer.
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Academic Article
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Refining epidermal growth factor receptor (EGFR) -inhibition-related rash (EIRR) phenotypes with a cetuximab (C) monotherapy stage of a phase II trial for non-small cell lung cancer (NSCLC).
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Academic Article
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Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer.
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Academic Article
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MET in Lung Cancer: Biomarker Selection Based on Scientific Rationale.
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Academic Article
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Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer.
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Academic Article
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Acute myeloid leukemia cells require 6-phosphogluconate dehydrogenase for cell growth and NADPH-dependent metabolic reprogramming.
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Academic Article
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2'-Hydroxyflavanone inhibits in vitro and in vivo growth of breast cancer cells by targeting RLIP76.
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Academic Article
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Correction: Nuclear Epidermal Growth Factor Receptor Is a Functional Molecular Target in Triple-negative Breast Cancer.
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Academic Article
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Ubiquitin-specific protease 22 is critical to in vivo angiogenesis, growth and metastasis of non-small cell lung cancer.
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Academic Article
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Targeting RLIP with CRISPR/Cas9 controls tumor growth.
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Academic Article
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Inhibitors of the Transcription Factor STAT3 Decrease Growth and Induce Immune Response Genes in Models of Malignant Pleural Mesothelioma (MPM).
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Academic Article
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Exploring the Next Frontier in Non-Small-Cell Lung Cancer With High MET and Mutated Epidermal Growth Factor Receptor.
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Academic Article
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MicroRNA-1 attenuates the growth and metastasis of small cell lung cancer through CXCR4/FOXM1/RRM2 axis.
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Academic Article
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RLIP: A necessary transporter protein for translating oxidative stress into pro-obesity and pro-carcinogenic signaling.
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Concept
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Inhibitor of Growth Protein 1
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Grant
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Role of Paxillin in Lung Cancer
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Grant
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MINIMAL RESIDUAL TUMOR IN SMALL CELL LUNG CANCER
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Grant
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Novel Targeted Therapy in Pancreatic Cancer
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Grant
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Studies of a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC)
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Grant
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PAXILLIN--AN ONCOGENE ACTIVATED PROTEIN
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