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Leff, Alan
One or more keywords matched the following items that are connected to
Leff, Alan
Item Type
Name
Concept
Phospholipases A
Concept
Type C Phospholipases
Concept
Phosphoinositide Phospholipase C
Concept
Phospholipase C beta
Concept
Group V Phospholipases A2
Concept
Group IV Phospholipases A2
Concept
Phospholipases A2
Concept
Phospholipase C gamma
Academic Article
Regulation of human eosinophil degranulation and activation by endogenous phospholipase A2.
Academic Article
Quantitation of the cytosolic phospholipase A2 (type IV) in isolated human peripheral blood eosinophils by sandwich-ELISA.
Academic Article
Characterization of monoclonal antibodies specific for 14-kDa human group V secretory phospholipase A2 (hVPLA2).
Academic Article
Cytosolic phospholipase A2 activation is essential for beta 1 and beta 2 integrin-dependent adhesion of human eosinophils.
Academic Article
Blockade of eosinophil migration and airway hyperresponsiveness by cPLA2-inhibition.
Academic Article
Extracellular signal-regulated kinase 1/2-mediated phosphorylation of cytosolic phospholipase A2 is essential for human eosinophil adhesion to fibronectin.
Academic Article
Regulation of eosinophil function by phosphatidylinositol-specific PLC and cytosolic PLA(2).
Academic Article
Roles of Trp31 in high membrane binding and proinflammatory activity of human group V phospholipase A2.
Academic Article
Mechanism of human group V phospholipase A2 (PLA2)-induced leukotriene biosynthesis in human neutrophils. A potential role of heparan sulfate binding in PLA2 internalization and degradation.
Academic Article
Regulation of adhesion of AML14.3D10 cells by surface clustering of beta2-integrin caused by ERK-independent activation of cPLA2.
Academic Article
Role of mitogen-activated protein kinase-mediated cytosolic phospholipase A2 activation in arachidonic acid metabolism in human eosinophils.
Academic Article
Quantitation of secretory group V phospholipase A(2) in human tissues by sandwich enzyme-linked immunosorbent assay.
Academic Article
Human group V phospholipase A2 induces group IVA phospholipase A2-independent cysteinyl leukotriene synthesis in human eosinophils.
Academic Article
Group V phospholipase A2 induces leukotriene biosynthesis in human neutrophils through the activation of group IVA phospholipase A2.
Academic Article
Blockade of LTC4 synthesis caused by additive inhibition of gIV-PLA2 phosphorylation: Effect of salmeterol and PDE4 inhibition in human eosinophils.
Academic Article
Activation of group IV cytosolic phospholipase A2 in human eosinophils by phosphoinositide 3-kinase through a mitogen-activated protein kinase-independent pathway.
Academic Article
Glucocorticoid-induced surface expression of annexin 1 blocks beta2-integrin adhesion of human eosinophils to intercellular adhesion molecule 1 surrogate protein.
Academic Article
Beta2-integrin adhesion caused by eotaxin but not IL-5 is blocked by PDE-4 inhibition and beta2-adrenoceptor activation in human eosinophils.
Academic Article
Additive blockade of beta 2-integrin adhesion of eosinophils by salmeterol and fluticasone propionate.
Academic Article
Deletion of secretory group V phospholipase A2 attenuates cell migration and airway hyperresponsiveness in immunosensitized mice.
Academic Article
Future treatment to lessen exacerbations of chronic obstructive pulmonary disease.
Academic Article
Secretory group V phospholipase A2 regulates acute lung injury and neutrophilic inflammation caused by LPS in mice.
Academic Article
Cytosolic group IVa phospholipase A2 mediates IL-8/CXCL8-induced transmigration of human polymorphonuclear leukocytes in vitro.
Academic Article
Transcellular secretion of group V phospholipase A2 from epithelium induces beta 2-integrin-mediated adhesion and synthesis of leukotriene C4 in eosinophils.
Academic Article
Group V phospholipase A(2) increases pulmonary endothelial permeability through direct hydrolysis of the cell membrane.
Academic Article
Group V phospholipase A2 mediates barrier disruption of human pulmonary endothelial cells caused by LPS in vitro.
Academic Article
Inhibition of cPLA2 translocation and leukotriene C4 secretion by fluticasone propionate in exogenously activated human eosinophils.
Academic Article
Direct effects and augmentation of airway smooth muscle contraction caused by phospholipase A2.
Academic Article
IL-5-induced integrin adhesion of human eosinophils caused by ERK1/2-mediated activation of cPLA2.
Academic Article
Attenuated translocation of group IVa phospholipase A2 and up-regulated annexin-1 synthesis by glucocorticoid blocks beta 2-integrin adhesion in neutrophils.
Academic Article
Mechanical induction of group V phospholipase A(2) causes lung inflammation and acute lung injury.
Grant
MECHANISMS OF AIRWAY HYPERRESPONSIVENESS
Search Criteria
Phospholipases