| Item Type | Name |
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Concept
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Muscle, Smooth
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Concept
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Muscles
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Concept
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Muscle, Smooth, Vascular
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Concept
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Muscle Tonus
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Concept
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Mitochondria, Muscle
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Concept
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Muscle Contraction
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Concept
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Myocytes, Smooth Muscle
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Concept
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Muscle Relaxation
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Academic Article
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Opposing effects of oxidants and antioxidants on K+ channel activity and tone in rat vascular tissue.
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Academic Article
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Differential distribution of electrophysiologically distinct myocytes in conduit and resistance arteries determines their response to nitric oxide and hypoxia.
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Academic Article
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Diversity of response in vascular smooth muscle cells to changes in oxygen tension.
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Academic Article
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Activation of the cGMP-dependent protein kinase mimics the stimulatory effect of nitric oxide and cGMP on calcium-gated potassium channels.
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Academic Article
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Oxygen causes fetal pulmonary vasodilation through activation of a calcium-dependent potassium channel.
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Academic Article
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Potassium channel diversity in vascular smooth muscle cells.
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Academic Article
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Effects of fluoxetine, phentermine, and venlafaxine on pulmonary arterial pressure and electrophysiology.
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Academic Article
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Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes.
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Academic Article
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Pulmonary vasoconstriction, oxygen sensing, and the role of ion channels: Thomas A. Neff lecture.
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Academic Article
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A maturational shift in pulmonary K+ channels, from Ca2+ sensitive to voltage dependent.
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Academic Article
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Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage-gated potassium channel Kv1.5.
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Academic Article
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Dexfenfluramine increases pulmonary artery smooth muscle intracellular Ca2+, independent of membrane potential.
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Academic Article
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Dexfenfluramine elevates systemic blood pressure by inhibiting potassium currents in vascular smooth muscle cells.
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Academic Article
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Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels.
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Academic Article
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Molecular identification of O2 sensors and O2-sensitive potassium channels in the pulmonary circulation.
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Academic Article
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Voltage-gated potassium channels in human ductus arteriosus.
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Academic Article
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In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats.
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Academic Article
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Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BK(Ca) channels.
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Academic Article
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Cellular and molecular pathobiology of pulmonary arterial hypertension.
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Academic Article
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The neurovascular mechanism of clitoral erection: nitric oxide and cGMP-stimulated activation of BKCa channels.
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Academic Article
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Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension.
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Academic Article
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Pre-B-cell colony-enhancing factor regulates vascular smooth muscle maturation through a NAD+-dependent mechanism: recognition of a new mechanism for cell diversity and redox regulation of vascular tone and remodeling.
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Academic Article
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An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.
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Academic Article
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Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells.
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Academic Article
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O2 sensing in the human ductus arteriosus: redox-sensitive K+ channels are regulated by mitochondria-derived hydrogen peroxide.
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Academic Article
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Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells.
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Academic Article
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Blunted hypoxic pulmonary vasoconstriction in experimental neonatal chronic lung disease.
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Academic Article
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The role of redox changes in oxygen sensing.
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Academic Article
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A central role for CD68(+) macrophages in hepatopulmonary syndrome. Reversal by macrophage depletion.
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Academic Article
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Developmental absence of the O2 sensitivity of L-type calcium channels in preterm ductus arteriosus smooth muscle cells impairs O2 constriction contributing to patent ductus arteriosus.
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Academic Article
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Paracrine proliferative signaling by senescent cells in world health organization group 3 pulmonary hypertension: age corrupting youth?
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Academic Article
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Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension.
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Academic Article
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Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor.
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Academic Article
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Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target.
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Academic Article
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Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.
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Academic Article
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Redox status in the control of pulmonary vascular tone.
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Academic Article
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Diphenyleneiodonium inhibits both potassium and calcium currents in isolated pulmonary artery smooth muscle cells.
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Academic Article
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A redox-based O2 sensor in rat pulmonary vasculature.
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Academic Article
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Diversity of phenotype and function of vascular smooth muscle cells.
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Academic Article
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Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction.
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Academic Article
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NG-monomethyl-L-arginine causes nitric oxide synthesis in isolated arterial rings: trouble in paradise.
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Academic Article
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The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels.
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Academic Article
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A role for potassium channels in smooth muscle cells and platelets in the etiology of primary pulmonary hypertension.
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Academic Article
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Potassium channels regulate tone in rat pulmonary veins.
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Academic Article
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Diversity in mitochondrial function explains differences in vascular oxygen sensing.
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Academic Article
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O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor.
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Academic Article
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Pergolide is an inhibitor of voltage-gated potassium channels, including Kv1.5, and causes pulmonary vasoconstriction.
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Academic Article
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Pathways of proliferation: new targets to inhibit the growth of vascular smooth muscle cells.
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Academic Article
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PGC1a-mediated mitofusin-2 deficiency in female rats and humans with pulmonary arterial hypertension.
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Academic Article
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Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus.
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Academic Article
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Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications.
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Academic Article
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Activation of the EGFR/p38/JNK pathway by mitochondrial-derived hydrogen peroxide contributes to oxygen-induced contraction of ductus arteriosus.
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Academic Article
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MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype.
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Academic Article
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Mitochondrial dynamics in pulmonary arterial hypertension.
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Academic Article
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A mitochondrial redox oxygen sensor in the pulmonary vasculature and ductus arteriosus.
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Academic Article
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Relevant issues in the pathology and pathobiology of pulmonary hypertension.
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Academic Article
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Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction.
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Academic Article
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The molecular mechanisms of oxygen-sensing in human ductus arteriosus smooth muscle cells: A comprehensive transcriptome profile reveals a central role for mitochondria.
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Academic Article
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Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra-coronary aortic banding.
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Academic Article
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The comprehensive transcriptome of human ductus arteriosus smooth muscle cells (hDASMC).
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Grant
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Impaired mitochondrial fusion in pulmonary arterial hypertension
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Grant
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O2 sensing in the human and rabbit ductus arteriosus.
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Grant
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EDRF IN NORMAL AND HYPERTENSIVE PULMONARY VASCULATURE
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Grant
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The Role of DRP-1 and Mitochondrial Fission in Pulmonary Arterial Hypertension
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