| Item Type | Name |
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Concept
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Chromosomal Proteins, Non-Histone
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Concept
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Histone Deacetylases
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Concept
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Histones
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Concept
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Histone Acetyltransferases
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Concept
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Histone Deacetylase 1
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Concept
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Histone Demethylases
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Concept
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Histone Chaperones
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Concept
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Histone-Lysine N-Methyltransferase
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Concept
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Jumonji Domain-Containing Histone Demethylases
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Academic Article
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Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression.
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Academic Article
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Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.
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Academic Article
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Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker.
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Academic Article
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Regulation of histone modification and chromatin structure by the p53-PADI4 pathway.
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Academic Article
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Involvement of the tubulin tyrosine ligase-like family member 4 polyglutamylase in PELP1 polyglutamylation and chromatin remodeling in pancreatic cancer cells.
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Academic Article
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Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6).
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Academic Article
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Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway.
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Academic Article
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Critical role of lysine 134 methylation on histone H2AX for ?-H2AX production and DNA repair.
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Academic Article
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SMYD3 interacts with HTLV-1 Tax and regulates subcellular localization of Tax.
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Academic Article
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The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene.
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Academic Article
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ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain.
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Academic Article
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WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck.
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Academic Article
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Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G(1)/S transition.
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Academic Article
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Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells.
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Academic Article
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PCOTH, a novel gene overexpressed in prostate cancers, promotes prostate cancer cell growth through phosphorylation of oncoprotein TAF-Ibeta/SET.
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Academic Article
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Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells.
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Academic Article
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The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3.
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Academic Article
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RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation.
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Academic Article
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The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination.
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Academic Article
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MRG-binding protein contributes to colorectal cancer development.
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Academic Article
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Enhanced SMYD3 expression is essential for the growth of breast cancer cells.
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Academic Article
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The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.
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Academic Article
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A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
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Academic Article
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The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
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Academic Article
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The histone methyltransferase SMYD2 methylates PARP1 and promotes poly(ADP-ribosyl)ation activity in cancer cells.
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Academic Article
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Enhanced expression of EHMT2 is involved in the proliferation of cancer cells through negative regulation of SIAH1.
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Academic Article
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Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.
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Academic Article
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SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation.
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Academic Article
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Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers.
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Academic Article
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SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.
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Academic Article
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Critical roles of non-histone protein lysine methylation in human tumorigenesis.
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Academic Article
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A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5' flanking region of SMYD3 is a risk factor for human cancers.
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Academic Article
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Dysregulation of AKT Pathway by SMYD2-Mediated Lysine Methylation on PTEN.
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Academic Article
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Identification of the interleukin 4 receptor alpha gene as a direct target for p73.
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Academic Article
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PDZ-binding kinase/T-LAK cell-originated protein kinase, a putative cancer/testis antigen with an oncogenic activity in breast cancer.
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Academic Article
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SUV39H2 methylates and stabilizes LSD1 by inhibiting polyubiquitination in human cancer cells.
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Academic Article
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The NSD family of protein methyltransferases in human cancer.
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Academic Article
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PRMT1 promotes mitosis of cancer cells through arginine methylation of INCENP.
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Academic Article
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SUV420H1 enhances the phosphorylation and transcription of ERK1 in cancer cells.
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Academic Article
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Dysregulation of protein methyltransferases in human cancer: An emerging target class for anticancer therapy.
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Academic Article
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Automethylation of SUV39H2, an oncogenic histone lysine methyltransferase, regulates its binding affinity to substrate proteins.
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Academic Article
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Epigenetic inactivation of the deleted in lung and esophageal cancer 1 gene in nasopharyngeal carcinoma.
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Academic Article
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HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres.
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Academic Article
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WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck.
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Academic Article
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SMYD3-mediated lysine methylation in the PH domain is critical for activation of AKT1.
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Academic Article
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WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer.
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Academic Article
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Effects of SMYD2-mediated EML4-ALK methylation on the signaling pathway and growth in non-small-cell lung cancer cells.
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Academic Article
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Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization.
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Academic Article
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WHSC1 monomethylates histone H1 and induces stem-cell like features in squamous cell carcinoma of the head and neck.
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Academic Article
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Clinicopathologic significance of protein lysine methyltransferases in cancer.
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