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One or more keywords matched the following items that are connected to Rhodes, Christopher
Item TypeName
Concept Endopeptidases
Concept Aspartic Acid Endopeptidases
Concept Serine Endopeptidases
Academic Article Glucose-regulated translational control of proinsulin biosynthesis with that of the proinsulin endopeptidases PC2 and PC3 in the insulin-producing MIN6 cell line.
Academic Article Processing of proopiomelanocortin by insulin secretory granule proinsulin processing endopeptidases.
Academic Article The biosynthesis of the subtilisin-related proprotein convertase PC3, but no that of the PC2 convertase, is regulated by glucose in parallel to proinsulin biosynthesis in rat pancreatic islets.
Academic Article Specific co-ordinated regulation of PC3 and PC2 gene expression with that of preproinsulin in insulin-producing beta TC3 cells.
Academic Article Preferential cleavage of des-31,32-proinsulin over intact proinsulin by the insulin secretory granule type II endopeptidase. Implication of a favored route for prohormone processing.
Academic Article Proalbumin to albumin conversion by a proinsulin processing endopeptidase of insulin secretory granules.
Academic Article The inhibition of proinsulin-processing endopeptidase activities by active-site-directed peptides.
Academic Article Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic beta cell via two distinct site-specific endopeptidases.
Academic Article What beta-cell defect could lead to hyperproinsulinemia in NIDDM? Some clues from recent advances made in understanding the proinsulin-processing mechanism.
Academic Article Increased secretory demand rather than a defect in the proinsulin conversion mechanism causes hyperproinsulinemia in a glucose-infusion rat model of non-insulin-dependent diabetes mellitus.
Academic Article Proinsulin endopeptidase substrate specificities defined by site-directed mutagenesis of proinsulin.
Academic Article Ca(2+)-regulated serine protease associated with the nuclear scaffold.
Academic Article Fluorometric assay of a calcium-dependent, paired-basic processing endopeptidase present in insulinoma granules.
Academic Article PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE.
Academic Article The enzymology of proinsulin conversion.
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