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One or more keywords matched the following properties of Fung, John
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overview John J. Fung, M.D., Ph.D. is the Director of the UChicago Medicine Transplantation Institute. Prior to that, he served as Chairman of the Cleveland Clinic Health System Center for Transplantation, as well as the former Chief of the Division of Transplant Surgery at the University of Pittsburgh. With over 30 years of involvement in abdominal and cellular transplantation, he is also an accomplished immunologist. Dr. Fung received his B.A. from the Johns Hopkins University in 1975, followed by a Ph.D. in Immunology in 1980 and M.D. in 1982 from the University of Chicago. He completed his surgical residency at the University of Rochester, and a transplant surgery fellowship at the University of Pittsburgh, under the guidance of Dr. Thomas Starzl. Between 1987 and 1988, he served as Director of Histocompatibility Testing at the University of Rochester. In 1989, he joined the faculty at the University of Pittsburgh and held the tenured position as the inaugural Thomas E. Starzl Professor in Surgery. He joined the Cleveland Clinic in 2004 as the Chairman of the Department of General Surgery and Professor of Surgery at the Lerner College of Medicine at Case Western University. He also served as the Medical Director of Allogen Laboratory, one of the largest histocompatibility laboratories in the United States and oversaw transplantation services at five Cleveland Clinic facilities globally. In 2016, he was recruited to serve as the Director of the newly created University of Chicago Medicine Transplantation Institute. Dr. Fung is a member of numerous scientific and surgical societies and served as President of the International Liver Transplantation Society from 1997-1999. He is currently Secretary of the Transplantation Society. He has published over 1,000 articles and book chapters and serves on the editorial board for several medical journals. He is the immediate past Editor-in-Chief for Liver Transplantation, the highest impact factor specialty transplant journal. His principal research interests are in transplantation immunology, immunosuppressive therapies, and liver related immunology. In addition, he has received numerous prestigious lay and professional awards. His research interests are in transplant immunology, liver immunity, immnosuppression, and outcomes analysis. Dr. Fung is active in community affairs and has been a member of the Board of Directors at the Americans for Medical Progress and the Gift of Hope Organ Procurement Organization. He received an honorable discharge from the United States Army Reserve Medical Corps with the rank of Lieutenant Colonel. He and his wife, Beth have four children: Justin, Lauren, Brendan and Shannon.
One or more keywords matched the following items that are connected to Fung, John
Item TypeName
Concept Histocompatibility Antigens Class II
Concept Histocompatibility Testing
Concept Major Histocompatibility Complex
Concept Minor Histocompatibility Loci
Concept Histocompatibility
Concept Histocompatibility Antigens
Concept Histocompatibility Antigens Class I
Concept Minor Histocompatibility Antigens
Academic Article HLA and cross-reactive antigen group matching for cadaver kidney allocation.
Academic Article Augmentation of natural chimerism with donor bone marrow in orthotopic liver recipients.
Academic Article Combined liver-kidney transplants: allosensitization and recipient outcomes.
Academic Article Use of MHC class I or II "knock out" mice to delineate the role of these molecules in acceptance/rejection of xenografts.
Academic Article Immunopathology of antibodies as effectors of orthotopic liver allograft rejection.
Academic Article Liver graft induced donor specific unresponsiveness without class I and/or class II antigen differences.
Academic Article Liver-derived DEC205+B220+CD19- dendritic cells regulate T cell responses.
Academic Article Allogeneic hematolymphoid microchimerism and prevention of autoimmune disease in the rat. A relationship between allo- and autoimmunity.
Academic Article In vivo expansion of two distinct dendritic cells in mouse livers and its impact on liver immune regulation.
Academic Article A clinical trial combining donor bone marrow infusion and heart transplantation: intermediate-term results.
Academic Article Allogeneic orthotopic liver transplantation in mice: a preliminary study of rejection across well-defined MHC barriers.
Academic Article Costimulatory molecule-deficient dendritic cell progenitors (MHC class II+, CD80dim, CD86-) prolong cardiac allograft survival in nonimmunosuppressed recipients.
Academic Article The impact of positive T-cell lymphocytotoxic crossmatch on intestinal allograft rejection and survival.
Academic Article Hematolymphoid cell trafficking, microchimerism, and GVH reactions after liver, bone marrow, and heart transplantation.
Academic Article Systemic administration of cellular interleukin-10 can exacerbate cardiac allograft rejection in mice.
Academic Article The long-term efficacy of multivisceral transplantation.
Academic Article Explanation for loss of the HLA matching effect.
Academic Article Combined liver-kidney transplantation and the effect of preformed lymphocytotoxic antibodies.
Academic Article Transplantation unresponsiveness induced by liver allografts in mouse strains with various histocompatibility disparities.
Academic Article Increased bile duct complications and/or chronic rejection in crossmatch positive human liver allografts.
Academic Article Impact of donor MHC class I or class II antigen deficiency on first- and second-set rejection of mouse heart or liver allografts.
Academic Article Evolution of hepatitis B virus liver disease after hepatic replacement. Practical and theoretical considerations.
Academic Article The politics of grafting cadaver kidneys.
Academic Article High-Resolution HLA Typing for Sensitized Patients: Advances in Medicine and Science Require Us to Challenge Existing Paradigms.
Academic Article Propagation of cells expressing donor phenotype (MHC class I, II and Y-chromosome) from the bone marrow of murine liver allograft recipients in response to GM-CSF in vitro.
Academic Article Role of MHC class I and CD8(+) T cells in the pathogenesis of chronic rejection.
Academic Article Tolerance and chimerism in liver transplantation.
Academic Article The liver allograft, chronic (ductopenic) rejection, and microchimerism: what can they teach us?
Academic Article Presensitization by skin grafting from major histocompatibility complex class I or major histocompatibility complex class II deficient mice identifies class I antigens as inducers of allosensitization.
Academic Article Histocompatibility and liver transplant outcome. Does HLA exert a dualistic effect?
Academic Article The protection from humoral rejection given by a liver xenograft is species-specific and non-MHC restricted.
Academic Article Donor pretreatment with Flt-3 ligand augments antidonor cytotoxic T lymphocyte, natural killer, and lymphokine-activated killer cell activities within liver allografts and alters the pattern of intragraft apoptotic activity.
Academic Article A clinicopathological study of human liver allograft recipients harboring preformed IgG lymphocytotoxic antibodies.
Academic Article Should HLA mismatch acceptability for sensitized transplant candidates be determined at the high-resolution rather than the antigen level?
Academic Article Four-color flow cytometric analysis of peripheral blood donor cell chimerism.
Academic Article Enhancement of dendritic cell tolerogenicity by genetic modification using adenoviral vectors encoding cDNA for TGF beta 1.
Academic Article Use of prostaglandin E1 in crossmatch-negative liver transplant recipients treated with FK 506.
Academic Article The influence of hepatitis C virus genotypes on the outcome of liver transplantation.
Academic Article Interferon-gamma induced expression of MHC antigens facilitates identification of donor cells in chimeric transplant recipients.
Academic Article HLA histocompatibility and liver transplant survival.
Academic Article HLA antigen expression on cultured human arterial endothelial cells.
Academic Article Murine liver allograft transplantation: tolerance and donor cell chimerism.
Academic Article Detection of intrahepatic human islets following combined liver-islet allotransplantation.
Academic Article Presentation of MHC-disparate donor antigens predominantly by the indirect pathway results in the development of posttransplant vasculopathy: salutary effects of perioperative costimulatory blockade.
Academic Article Recognition of major histocompatibility complex antigens on cultured human biliary epithelial cells by alloreactive lymphocytes.
Academic Article Humoral rejection associated with antidonor lymphocytotoxic antibodies following liver transplantation.
Academic Article The lymphocytotoxic crossmatch in liver transplantation: a clinicopathologic analysis.
Academic Article The antibody crossmatch in liver transplantation.
Academic Article Prevention and restoration of second-set liver allograft rejection in presensitized mice: the role of "passenger" leukocytes, donor major histocompatibility complex antigens, and host cytotoxic effector mechanisms.
Academic Article In vitro propagation and homing of liver-derived dendritic cell progenitors to lymphoid tissues of allogeneic recipients. Implications for the establishment and maintenance of donor cell chimerism following liver transplantation.
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  • Histocompatibility