Sodium-Potassium-Exchanging ATPase
"Sodium-Potassium-Exchanging ATPase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the active transport system of sodium and potassium ions across the cell wall. Sodium and potassium ions are closely coupled with membrane ATPase which undergoes phosphorylation and dephosphorylation, thereby providing energy for transport of these ions against concentration gradients.
| Descriptor ID |
D000254
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| MeSH Number(s) |
D08.811.277.040.025.314.750 D12.776.157.530.450.162.780 D12.776.157.530.450.250.880 D12.776.157.530.813.750 D12.776.543.585.450.162.800 D12.776.543.585.450.250.890 D12.776.543.585.813.750
|
| Concept/Terms |
Sodium-Potassium-Exchanging ATPase- Sodium-Potassium-Exchanging ATPase
- ATPase, Sodium-Potassium-Exchanging
- Sodium Potassium Exchanging ATPase
- Sodium, Potassium Adenosinetriphosphatase
- Adenosinetriphosphatase Sodium, Potassium
- ATPase, Sodium, Potassium
- Sodium, Potassium ATPase
- ATPase Sodium, Potassium
- Potassium Pump
- Pump, Potassium
- Sodium, Potassium Adenosine Triphosphatase
- Sodium-Potassium Pump
- Pump, Sodium-Potassium
- Sodium Potassium Pump
- Na(+) K(+)-Transporting ATPase
- Na(+)-K(+)-Transporting ATPase
- Na(+)-K(+)-Exchanging ATPase
- Adenosine Triphosphatase, Sodium, Potassium
- Adenosinetriphosphatase, Sodium, Potassium
- Sodium Pump
- Pump, Sodium
|
Below are MeSH descriptors whose meaning is more general than "Sodium-Potassium-Exchanging ATPase".
Below are MeSH descriptors whose meaning is more specific than "Sodium-Potassium-Exchanging ATPase".
This graph shows the total number of publications written about "Sodium-Potassium-Exchanging ATPase" by people in this website by year, and whether "Sodium-Potassium-Exchanging ATPase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 2 | 0 | 2 |
| 1994 | 0 | 1 | 1 |
| 1995 | 1 | 1 | 2 |
| 1996 | 1 | 0 | 1 |
| 1997 | 2 | 0 | 2 |
| 1998 | 1 | 0 | 1 |
| 2000 | 0 | 3 | 3 |
| 2001 | 1 | 1 | 2 |
| 2002 | 4 | 3 | 7 |
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 2 | 3 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 3 | 1 | 4 |
| 2008 | 2 | 0 | 2 |
| 2009 | 2 | 1 | 3 |
| 2011 | 2 | 1 | 3 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 4 | 0 | 4 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 0 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2023 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Sodium-Potassium-Exchanging ATPase" by people in Profiles.
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Cation leak through the ATP1A3 pump causes spasticity and intellectual disability. Brain. 2023 08 01; 146(8):3162-3171.
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The ion transporter Na+-K+-ATPase enables pathological B cell survival in the kidney microenvironment of lupus nephritis. Sci Adv. 2023 02 03; 9(5):eadf8156.
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ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria. Brain. 2021 06 22; 144(5):1435-1450.
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Transient Electrical Currents Mediated by the Na+/K+-ATPase: A Tour from Basic Biophysics to Human Diseases. Biophys J. 2020 07 21; 119(2):236-242.
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Biallelic loss of function variants in ATP1A2 cause hydrops fetalis, microcephaly, arthrogryposis and extensive cortical malformations. Eur J Med Genet. 2020 Jan; 63(1):103624.
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Na+,K+-ATPase as a Target for Treatment of Tissue Fibrosis. Curr Med Chem. 2019; 26(3):564-575.
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Telocinobufagin, a Novel Cardiotonic Steroid, Promotes Renal Fibrosis via Na?/K?-ATPase Profibrotic Signaling Pathways. Int J Mol Sci. 2018 Aug 29; 19(9).
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Disruption of the lens circulation causes calcium accumulation and precipitates in connexin mutant mice. Am J Physiol Cell Physiol. 2018 04 01; 314(4):C492-C503.
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Fever-Induced Paroxysmal Weakness and Encephalopathy, a New Phenotype of ATP1A3 Mutation. Pediatr Neurol. 2017 Aug; 73:101-105.
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Downregulation of TGF-ß Receptor-2 Expression and Signaling through Inhibition of Na/K-ATPase. PLoS One. 2016; 11(12):e0168363.