 Sodium-Potassium-Exchanging ATPase
"Sodium-Potassium-Exchanging ATPase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the active transport system of sodium and potassium ions across the cell wall. Sodium and potassium ions are closely coupled with membrane ATPase which undergoes phosphorylation and dephosphorylation, thereby providing energy for transport of these ions against concentration gradients.
| Descriptor ID |
D000254
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| MeSH Number(s) |
D08.811.277.040.025.810 D12.776.157.530.450.162.780 D12.776.157.530.450.250.880 D12.776.543.585.450.162.800 D12.776.543.585.450.250.890
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| Concept/Terms |
Sodium-Potassium-Exchanging ATPase- Sodium-Potassium-Exchanging ATPase
- ATPase, Sodium-Potassium-Exchanging
- Sodium Potassium Exchanging ATPase
- Adenosinetriphosphatase, Sodium, Potassium
- ATPase, Sodium, Potassium
- Na(+) K(+)-Transporting ATPase
- Na(+)-K(+)-Exchanging ATPase
- Sodium-Potassium Pump
- Pump, Sodium-Potassium
- Sodium Potassium Pump
- Potassium Pump
- Pump, Potassium
- Sodium Pump
- Pump, Sodium
- Sodium, Potassium Adenosine Triphosphatase
- Sodium, Potassium Adenosinetriphosphatase
- Adenosinetriphosphatase Sodium, Potassium
- Sodium, Potassium ATPase
- ATPase Sodium, Potassium
- Adenosine Triphosphatase, Sodium, Potassium
- Na(+)-K(+)-Transporting ATPase
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Below are MeSH descriptors whose meaning is more general than "Sodium-Potassium-Exchanging ATPase".
Below are MeSH descriptors whose meaning is more specific than "Sodium-Potassium-Exchanging ATPase".
This graph shows the total number of publications written about "Sodium-Potassium-Exchanging ATPase" by people in this website by year, and whether "Sodium-Potassium-Exchanging ATPase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 1982 | 1 | 0 | 1 | | 1983 | 0 | 1 | 1 | | 1988 | 1 | 1 | 2 | | 1990 | 1 | 0 | 1 | | 1992 | 1 | 2 | 3 | | 1993 | 2 | 0 | 2 | | 1994 | 0 | 1 | 1 | | 1995 | 1 | 1 | 2 | | 1996 | 1 | 0 | 1 | | 1997 | 2 | 0 | 2 | | 1998 | 1 | 0 | 1 | | 2000 | 0 | 2 | 2 | | 2001 | 1 | 1 | 2 | | 2002 | 4 | 3 | 7 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 2 | 3 | | 2005 | 0 | 2 | 2 | | 2006 | 0 | 1 | 1 | | 2007 | 3 | 1 | 4 | | 2008 | 2 | 0 | 2 | | 2009 | 3 | 1 | 4 | | 2011 | 2 | 1 | 3 | | 2012 | 1 | 1 | 2 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 4 | 0 | 4 | | 2016 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 | | 2019 | 2 | 0 | 2 | | 2020 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sodium-Potassium-Exchanging ATPase" by people in Profiles.
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Vetro A, Nielsen HN, Holm R, Hevner RF, Parrini E, Powis Z, Møller RS, Bellan C, Simonati A, Lesca G, Helbig KL, Palmer EE, Mei D, Ballardini E, Van Haeringen A, Syrbe S, Leuzzi V, Cioni G, Curry CJ, Costain G, Santucci M, Chong K, Mancini GMS, Clayton-Smith J, Bigoni S, Scheffer IE, Dobyns WB, Vilsen B, Guerrini R. ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria. Brain. 2021 06 22; 144(5):1435-1450.
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Moreno C, Yano S, Bezanilla F, Latorre R, Holmgren M. Transient Electrical Currents Mediated by the Na+/K+-ATPase: A Tour from Basic Biophysics to Human Diseases. Biophys J. 2020 07 21; 119(2):236-242.
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Monteiro FP, Curry CJ, Hevner R, Elliott S, Fisher JH, Turocy J, Dobyns WB, Costa LA, Freitas E, Kitajima JP, Kok F. Biallelic loss of function variants in ATP1A2 cause hydrops fetalis, microcephaly, arthrogryposis and extensive cortical malformations. Eur J Med Genet. 2020 Jan; 63(1):103624.
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Orlov SN, La J, Smolyaninova LV, Dulin NO. Na+,K+-ATPase as a Target for Treatment of Tissue Fibrosis. Curr Med Chem. 2019; 26(3):564-575.
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Gao J, Minogue PJ, Beyer EC, Mathias RT, Berthoud VM. Disruption of the lens circulation causes calcium accumulation and precipitates in connexin mutant mice. Am J Physiol Cell Physiol. 2018 04 01; 314(4):C492-C503.
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Yano ST, Silver K, Young R, DeBrosse SD, Ebel RS, Swoboda KJ, Acsadi G. Fever-Induced Paroxysmal Weakness and Encephalopathy, a New Phenotype of ATP1A3 Mutation. Pediatr Neurol. 2017 Aug; 73:101-105.
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La J, Reed E, Chan L, Smolyaninova LV, Akomova OA, Mutlu GM, Orlov SN, Dulin NO. Downregulation of TGF-ß Receptor-2 Expression and Signaling through Inhibition of Na/K-ATPase. PLoS One. 2016; 11(12):e0168363.
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Rui H, Artigas P, Roux B. The selectivity of the Na(+)/K(+)-pump is controlled by binding site protonation and self-correcting occlusion. Elife. 2016 08 04; 5.
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Peteranderl C, Morales-Nebreda L, Selvakumar B, Lecuona E, Vadász I, Morty RE, Schmoldt C, Bespalowa J, Wolff T, Pleschka S, Mayer K, Gattenloehner S, Fink L, Lohmeyer J, Seeger W, Sznajder JI, Mutlu GM, Budinger GR, Herold S. Macrophage-epithelial paracrine crosstalk inhibits lung edema clearance during influenza infection. J Clin Invest. 2016 Apr 01; 126(4):1566-80.
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Huang H, Chen YM, Zhu F, Tang ST, Xiao JD, Li LL, Lin XJ. Down-regulated Na(+)/K(+)-ATPase activity in ischemic penumbra after focal cerebral ischemia/reperfusion in rats. Int J Clin Exp Pathol. 2015; 8(10):12708-17.
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