"Complement Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The sequential activation of serum COMPLEMENT PROTEINS to create the COMPLEMENT MEMBRANE ATTACK COMPLEX. Factors initiating complement activation include ANTIGEN-ANTIBODY COMPLEXES, microbial ANTIGENS, or cell surface POLYSACCHARIDES.
| Descriptor ID |
D003167
|
| MeSH Number(s) |
G12.274
|
| Concept/Terms |
Complement Activation- Complement Activation
- Activation, Complement
- Activations, Complement
- Complement Activations
|
Below are MeSH descriptors whose meaning is more general than "Complement Activation".
Below are MeSH descriptors whose meaning is more specific than "Complement Activation".
This graph shows the total number of publications written about "Complement Activation" by people in this website by year, and whether "Complement Activation" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 1 | 2 |
| 1998 | 1 | 1 | 2 |
| 1999 | 1 | 2 | 3 |
| 2000 | 2 | 0 | 2 |
| 2001 | 1 | 1 | 2 |
| 2002 | 0 | 3 | 3 |
| 2003 | 2 | 0 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 2 | 3 |
| 2007 | 5 | 3 | 8 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 4 | 5 |
| 2010 | 1 | 3 | 4 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2015 | 0 | 3 | 3 |
| 2016 | 1 | 2 | 3 |
| 2017 | 0 | 1 | 1 |
| 2020 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Complement Activation" by people in Profiles.
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Complement: Functions, location and implications. Immunology. 2023 10; 170(2):180-192.
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Engineered human antibodies for the opsonization and killing of Staphylococcus aureus. Proc Natl Acad Sci U S A. 2022 01 25; 119(4).
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Complement and Renal Thrombotic Microangiopathy Associated With Hypertension and Scleroderma. Adv Chronic Kidney Dis. 2020 03; 27(2):149-154.
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Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension. Am J Respir Crit Care Med. 2020 01 15; 201(2):224-239.
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Immunomodulatory Role of Complement Proteins in the Neuropathology Associated with Opiate Abuse and HIV-1 Co-Morbidity. Immunol Invest. 2017 Nov; 46(8):816-832.
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Local Inhibition of Complement Improves Mesenchymal Stem Cell Viability and Function After Administration. Mol Ther. 2016 09; 24(9):1665-74.
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Painting factor H onto mesenchymal stem cells protects the cells from complement- and neutrophil-mediated damage. Biomaterials. 2016 09; 102:209-19.
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Presence of retinal pericyte-reactive autoantibodies in diabetic retinopathy patients. Sci Rep. 2016 Feb 03; 6:20341.
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Staphylococcal manipulation of host immune responses. Nat Rev Microbiol. 2015 Sep; 13(9):529-43.
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C5a alters blood-brain barrier integrity in a human in vitro model of systemic lupus erythematosus. Immunology. 2015 Sep; 146(1):130-43.