"Binding Sites, Antibody" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Local surface sites on antibodies which react with antigen determinant sites on antigens (EPITOPES.) They are formed from parts of the variable regions of FAB FRAGMENTS.
| Descriptor ID |
D001666
|
| MeSH Number(s) |
G02.111.570.060.425.079 G02.111.570.120.408 G12.122.232 G12.125
|
| Concept/Terms |
Binding Sites, Antibody- Binding Sites, Antibody
- Antibody Binding Site
- Binding Site, Antibody
- Paratopes
- Paratope
- Antibody Binding Sites
|
Below are MeSH descriptors whose meaning is more general than "Binding Sites, Antibody".
Below are MeSH descriptors whose meaning is more specific than "Binding Sites, Antibody".
This graph shows the total number of publications written about "Binding Sites, Antibody" by people in this website by year, and whether "Binding Sites, Antibody" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
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click here.
Below are the most recent publications written about "Binding Sites, Antibody" by people in Profiles.
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Influenza hemagglutinin-specific IgA Fc-effector functionality is restricted to stalk epitopes. Proc Natl Acad Sci U S A. 2021 02 23; 118(8).
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A polar ring endows improved specificity to an antibody fragment. Protein Sci. 2016 07; 25(7):1290-8.
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Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation. Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8):2092-7.
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Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site. Protein Eng Des Sel. 2014 Oct; 27(10):391-7.
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Recombinant antibodies to histone post-translational modifications. Nat Methods. 2013 Oct; 10(10):992-5.
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Protein A-specific monoclonal antibodies and prevention of Staphylococcus aureus disease in mice. Infect Immun. 2012 Oct; 80(10):3460-70.
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A combinatorial approach to engineering a dual-specific metal switch antibody. Biochemistry. 2011 Jun 14; 50(23):5093-5.
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Exploring the capacity of minimalist protein interfaces: interface energetics and affinity maturation to picomolar KD of a single-domain antibody with a flat paratope. J Mol Biol. 2007 Nov 02; 373(4):941-53.
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Development and selection of edited B cells in B6.56R mice. J Immunol. 2006 Jun 01; 176(11):6879-87.
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Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity. Mol Endocrinol. 2004 Dec; 18(12):3020-34.