 Cystine
"Cystine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A covalently linked dimeric nonessential amino acid formed by the oxidation of CYSTEINE. Two molecules of cysteine are joined together by a disulfide bridge to form cystine.
| Descriptor ID |
D003553
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| MeSH Number(s) |
D01.248.497.158.874.390.369 D01.875.350.850.150.369 D02.886.030.230.369 D02.886.520.150.087 D12.125.095.369 D12.125.119.369 D12.125.166.230.369
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cystine".
Below are MeSH descriptors whose meaning is more specific than "Cystine".
This graph shows the total number of publications written about "Cystine" by people in this website by year, and whether "Cystine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 1 | 1 | | 1997 | 0 | 2 | 2 | | 1998 | 0 | 1 | 1 | | 2006 | 3 | 0 | 3 | | 2008 | 0 | 1 | 1 | | 2010 | 2 | 0 | 2 | | 2012 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cystine" by people in Profiles.
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Eisner BH, Goldfarb DS, Baum MA, Langman CB, Curhan GC, Preminger GM, Lieske JC, Pareek G, Thomas K, Zisman AL, Papagiannopoulos D, Sur RL. Evaluation and Medical Management of Patients with Cystine Nephrolithiasis: A Consensus Statement. J Endourol. 2020 11; 34(11):1103-1110.
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Malieckal DA, Modersitzki F, Mara K, Enders FT, Asplin JR, Goldfarb DS. Effect of increasing doses of cystine-binding thiol drugs on cystine capacity in patients with cystinuria. Urolithiasis. 2019 Dec; 47(6):549-555.
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Muir A, Danai LV, Gui DY, Waingarten CY, Lewis CA, Vander Heiden MG. Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition. Elife. 2017 08 15; 6.
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Gaide Chevronnay HP, Janssens V, Van Der Smissen P, Rocca CJ, Liao XH, Refetoff S, Pierreux CE, Cherqui S, Courtoy PJ. Hematopoietic Stem Cells Transplantation Can Normalize Thyroid Function in a Cystinosis Mouse Model. Endocrinology. 2016 Apr; 157(4):1363-71.
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Ghasemzadeh N, Patel RS, Eapen DJ, Veledar E, Al Kassem H, Manocha P, Khayata M, Zafari AM, Sperling L, Jones DP, Quyyumi AA. Oxidative stress is associated with increased pulmonary artery systolic pressure in humans. Hypertension. 2014 Jun; 63(6):1270-5.
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Asplin DM, Asplin JR. The Interaction of thiol drugs and urine pH in the treatment of cystinuria. J Urol. 2013 Jun; 189(6):2147-51.
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Coe FL, Asplin JR. Medicine. Stopping the stones. Science. 2010 Oct 15; 330(6002):325-6.
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Lambert EH, Asplin JR, Herrell SD, Miller NL. Analysis of 24-hour urine parameters as it relates to age of onset of cystine stone formation. J Endourol. 2010 Jul; 24(7):1179-82.
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Parks JH, Coe FL. Evidence for durable kidney stone prevention over several decades. BJU Int. 2009 May; 103(9):1238-46.
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Worcester EM, Coe FL, Evan AP, Parks JH. Reduced renal function and benefits of treatment in cystinuria vs other forms of nephrolithiasis. BJU Int. 2006 Jun; 97(6):1285-90.
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