Fibroblast Growth Factors
"Fibroblast Growth Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of small polypeptide growth factors that share several common features including a strong affinity for HEPARIN, and a central barrel-shaped core region of 140 amino acids that is highly homologous between family members. Although originally studied as proteins that stimulate the growth of fibroblasts this distinction is no longer a requirement for membership in the fibroblast growth factor family.
| Descriptor ID |
D005346
|
| MeSH Number(s) |
D12.644.276.624 D12.776.467.624 D23.529.624
|
| Concept/Terms |
Fibroblast Growth Factors- Fibroblast Growth Factors
- Growth Factors, Fibroblast
- Fibroblast Growth Factor
- Growth Factor, Fibroblast
- Fibroblast Growth Regulatory Factor
- DNA Synthesis Factor
|
Below are MeSH descriptors whose meaning is more general than "Fibroblast Growth Factors".
Below are MeSH descriptors whose meaning is more specific than "Fibroblast Growth Factors".
This graph shows the total number of publications written about "Fibroblast Growth Factors" by people in this website by year, and whether "Fibroblast Growth Factors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 |
| 1996 | 1 | 1 | 2 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 2 | 3 |
| 1999 | 1 | 2 | 3 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 3 | 2 | 5 |
| 2004 | 2 | 3 | 5 |
| 2005 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 2 | 3 |
| 2012 | 1 | 1 | 2 |
| 2013 | 3 | 5 | 8 |
| 2014 | 1 | 1 | 2 |
| 2015 | 5 | 2 | 7 |
| 2016 | 1 | 1 | 2 |
| 2017 | 2 | 1 | 3 |
| 2018 | 3 | 0 | 3 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 3 | 3 |
| 2021 | 1 | 1 | 2 |
| 2022 | 2 | 1 | 3 |
| 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Fibroblast Growth Factors" by people in Profiles.
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A randomized, double-blind, placebo-controlled trial of aldafermin in patients with NASH and compensated cirrhosis. Hepatology. 2024 Mar 01; 79(3):674-689.
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Pegozafermin for NASH - A Sprint to Start a Marathon. N Engl J Med. 2023 Sep 14; 389(11):1044-1046.
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From the Gut to the Lung: Evidence of Antifibrotic Activity of Endocrine Fibroblast Growth Factor 19. Am J Respir Cell Mol Biol. 2022 08; 67(2):139-141.
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Association of Genetically Predicted Fibroblast Growth Factor-23 with Heart Failure: A Mendelian Randomization Study. Clin J Am Soc Nephrol. 2022 08; 17(8):1183-1193.
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Aldafermin in patients with non-alcoholic steatohepatitis (ALPINE 2/3): a randomised, double-blind, placebo-controlled, phase 2b trial. Lancet Gastroenterol Hepatol. 2022 07; 7(7):603-616.
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An Fgf-Shh positive feedback loop drives growth in developing unpaired fins. Proc Natl Acad Sci U S A. 2022 03 08; 119(10):e2120150119.
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BAd-CRISPR: Inducible gene knockout in interscapular brown adipose tissue of adult mice. J Biol Chem. 2021 12; 297(6):101402.
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Tbx5a and Tbx5b paralogues act in combination to control separate vectors of migration in the fin field of zebrafish. Dev Biol. 2022 01; 481:201-214.
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A theoretical model of neural maturation in the developing chick spinal cord. PLoS One. 2020; 15(12):e0244219.
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Fibroblast Growth Factor Inhibitors in Lung Fibrosis: Friends or Foes? Am J Respir Cell Mol Biol. 2020 09; 63(3):273-274.