"Serrate-Jagged Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins that consist of multiple extracellular EPIDERMAL GROWTH FACTOR - like repeat sequences (EGF repeats), including calcium-binding EGF repeats. They function as transmembrane ligands for NOTCH RECEPTORS to control CELL DIFFERENTIATION during development.
| Descriptor ID |
D000072099
|
| MeSH Number(s) |
D12.644.276.930 D12.776.157.125.797 D12.776.543.800 D23.529.930
|
| Concept/Terms |
Serrate-Jagged Proteins- Serrate-Jagged Proteins
- Serrate Jagged Proteins
- Jagged Proteins
- Serrate Protein
- Serrate Proteins
|
Below are MeSH descriptors whose meaning is more general than "Serrate-Jagged Proteins".
Below are MeSH descriptors whose meaning is more specific than "Serrate-Jagged Proteins".
This graph shows the total number of publications written about "Serrate-Jagged Proteins" by people in this website by year, and whether "Serrate-Jagged Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Serrate-Jagged Proteins" by people in Profiles.
-
Vascular endothelial growth factor (VEGF) induced proliferation of human fetal derived ciliary epithelium stem cells is mediated by jagged-N cadherin pathway. Curr Neurovasc Res. 2013 May; 10(2):93-102.
-
Endocardial to myocardial notch-wnt-bmp axis regulates early heart valve development. PLoS One. 2013; 8(4):e60244.
-
Notch-1 and notch-4 receptors as prognostic markers in breast cancer. Int J Surg Pathol. 2011 Oct; 19(5):607-13.
-
A notch1 ectodomain construct inhibits endothelial notch signaling, tumor growth, and angiogenesis. Cancer Res. 2008 Jun 15; 68(12):4727-35.
-
Progression of intracranial glioma disrupts thymic homeostasis and induces T-cell apoptosis in vivo. Cancer Immunol Immunother. 2008 Dec; 57(12):1807-16.
-
Complementation of human papillomavirus type 16 E6 and E7 by Jagged1-specific Notch1-phosphatidylinositol 3-kinase signaling involves pleiotropic oncogenic functions independent of CBF1;Su(H);Lag-1 activation. J Virol. 2005 Jun; 79(12):7889-98.
-
Papillomavirus-mediated neoplastic progression is associated with reciprocal changes in JAGGED1 and manic fringe expression linked to notch activation. J Virol. 2004 Aug; 78(16):8687-700.
-
Tetralogy of fallot and other congenital heart defects in Hey2 mutant mice. Curr Biol. 2002 Sep 17; 12(18):1605-10.
-
The p53 family member genes are involved in the Notch signal pathway. J Biol Chem. 2002 Jan 04; 277(1):719-24.
-
The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti. Hum Mol Genet. 2001 Mar 01; 10(5):507-12.