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The spatial architecture of protein function and adaptation.
McLaughlin RN, Poelwijk FJ, Raman A, Gosal WS, Ranganathan R. The spatial architecture of protein function and adaptation. Nature. 2012 Nov 01; 491(7422):138-42.
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PubMed
subject areas
Adaptation, Physiological
Amino Acid Sequence
Amino Acid Substitution
Binding Sites
Evolution, Molecular
Ligands
Models, Molecular
Molecular Sequence Data
Mutant Proteins
Mutation
PDZ Domains
Proteins
authors with profiles
Rama Ranganathan
Arjun Raman
The spatial architecture of protein function and adaptation.