Dose-Response Relationship, Drug
"Dose-Response Relationship, Drug" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The relationship between the dose of an administered drug and the response of the organism to the drug.
| Descriptor ID |
D004305
|
| MeSH Number(s) |
G07.690.773.875 G07.690.936.500
|
| Concept/Terms |
Dose-Response Relationship, Drug- Dose-Response Relationship, Drug
- Dose-Response Relationships, Drug
- Drug Dose-Response Relationship
- Drug Dose-Response Relationships
- Relationship, Drug Dose-Response
- Relationships, Drug Dose-Response
- Dose Response Relationship, Drug
|
Below are MeSH descriptors whose meaning is more general than "Dose-Response Relationship, Drug".
Below are MeSH descriptors whose meaning is more specific than "Dose-Response Relationship, Drug".
This graph shows the total number of publications written about "Dose-Response Relationship, Drug" by people in this website by year, and whether "Dose-Response Relationship, Drug" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 39 | 39 |
| 1994 | 0 | 27 | 27 |
| 1995 | 0 | 28 | 28 |
| 1996 | 0 | 22 | 22 |
| 1997 | 0 | 28 | 28 |
| 1998 | 0 | 32 | 32 |
| 1999 | 0 | 34 | 34 |
| 2000 | 0 | 46 | 46 |
| 2001 | 0 | 53 | 53 |
| 2002 | 0 | 67 | 67 |
| 2003 | 1 | 70 | 71 |
| 2004 | 0 | 72 | 72 |
| 2005 | 0 | 63 | 63 |
| 2006 | 0 | 64 | 64 |
| 2007 | 1 | 58 | 59 |
| 2008 | 1 | 68 | 69 |
| 2009 | 1 | 51 | 52 |
| 2010 | 0 | 57 | 57 |
| 2011 | 1 | 57 | 58 |
| 2012 | 0 | 52 | 52 |
| 2013 | 0 | 42 | 42 |
| 2014 | 0 | 48 | 48 |
| 2015 | 3 | 43 | 46 |
| 2016 | 0 | 35 | 35 |
| 2017 | 0 | 29 | 29 |
| 2018 | 0 | 39 | 39 |
| 2019 | 0 | 33 | 33 |
| 2020 | 0 | 12 | 12 |
| 2021 | 1 | 13 | 14 |
| 2022 | 0 | 5 | 5 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dose-Response Relationship, Drug" by people in Profiles.
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A Multi-Arm Two-Stage (MATS) design for proof-of-concept and dose optimization in early-phase oncology trials. Contemp Clin Trials. 2023 09; 132:107278.
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Oncology phase I trial design and conduct: time for a change - MDICT Guidelines 2022. Ann Oncol. 2023 01; 34(1):48-60.
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Eftozanermin alfa (ABBV-621) monotherapy in patients with previously treated solid tumors: findings of a phase 1, first-in-human study. Invest New Drugs. 2022 08; 40(4):762-772.
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Higher vs Standard Adalimumab Induction Dosing Regimens and Two Maintenance Strategies: Randomized SERENE CD Trial Results. Gastroenterology. 2022 06; 162(7):1876-1890.
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Engineered human antibodies for the opsonization and killing of Staphylococcus aureus. Proc Natl Acad Sci U S A. 2022 01 25; 119(4).
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Decitabine potentiates efficacy of doxorubicin in a preclinical trastuzumab-resistant HER2-positive breast cancer models. Biomed Pharmacother. 2022 Mar; 147:112662.
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Pharmacokinetic Simulation Analysis of Less Frequent Nivolumab and Pembrolizumab Dosing: Pharmacoeconomic Rationale for Dose Deescalation. J Clin Pharmacol. 2022 04; 62(4):532-540.
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EDP-305 in patients with NASH: A phase II double-blind placebo-controlled dose-ranging study. J Hepatol. 2022 03; 76(3):506-517.
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Ethanol interaction with a3ß4 nicotinic acetylcholine receptors in neurons of the laterodorsal tegmentum. Alcohol Clin Exp Res. 2021 12; 45(12):2495-2505.
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Effect of Antithrombotic Therapy on Clinical Outcomes in Outpatients With Clinically Stable Symptomatic COVID-19: The ACTIV-4B Randomized Clinical Trial. JAMA. 2021 11 02; 326(17):1703-1712.