 Immune Tolerance
"Immune Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.
| Descriptor ID |
D007108
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| MeSH Number(s) |
G12.425.746.425
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Immune Tolerance".
Below are MeSH descriptors whose meaning is more specific than "Immune Tolerance".
This graph shows the total number of publications written about "Immune Tolerance" by people in this website by year, and whether "Immune Tolerance" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1982 | 1 | 1 | 2 | | 1983 | 1 | 0 | 1 | | 1984 | 4 | 2 | 6 | | 1986 | 0 | 1 | 1 | | 1987 | 0 | 1 | 1 | | 1988 | 2 | 2 | 4 | | 1989 | 0 | 2 | 2 | | 1990 | 0 | 1 | 1 | | 1991 | 0 | 3 | 3 | | 1992 | 0 | 1 | 1 | | 1993 | 4 | 5 | 9 | | 1994 | 3 | 3 | 6 | | 1995 | 2 | 4 | 6 | | 1996 | 2 | 2 | 4 | | 1997 | 5 | 6 | 11 | | 1998 | 0 | 2 | 2 | | 1999 | 4 | 2 | 6 | | 2000 | 5 | 2 | 7 | | 2001 | 6 | 4 | 10 | | 2002 | 3 | 1 | 4 | | 2003 | 4 | 3 | 7 | | 2004 | 3 | 3 | 6 | | 2005 | 5 | 5 | 10 | | 2006 | 9 | 4 | 13 | | 2007 | 2 | 3 | 5 | | 2008 | 3 | 4 | 7 | | 2009 | 1 | 6 | 7 | | 2010 | 4 | 5 | 9 | | 2011 | 9 | 4 | 13 | | 2012 | 7 | 5 | 12 | | 2013 | 4 | 6 | 10 | | 2014 | 7 | 6 | 13 | | 2015 | 7 | 3 | 10 | | 2016 | 7 | 1 | 8 | | 2017 | 8 | 4 | 12 | | 2018 | 1 | 4 | 5 | | 2019 | 4 | 4 | 8 |
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Below are the most recent publications written about "Immune Tolerance" by people in Profiles.
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Miller ML, McIntosh CM, Wang Y, Chen L, Wang P, Lei YM, Daniels MD, Watkins E, Mora Solano C, Chong AS, Alegre ML. Resilience of T cell-intrinsic dysfunction in transplantation tolerance. Proc Natl Acad Sci U S A. 2019 11 19; 116(47):23682-23690.
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Ciaccio CE, Bauer ME, Nowak-Wegrzyn A. Food OIT: What do we know, what don't we know, and what do we need to know? Ann Allergy Asthma Immunol. 2019 08; 123(2):118-119.
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Wilson DS, Damo M, Hirosue S, Raczy MM, Brünggel K, Diaceri G, Quaglia-Thermes X, Hubbell JA. Synthetically glycosylated antigens induce antigen-specific tolerance and prevent the onset of diabetes. Nat Biomed Eng. 2019 10; 3(10):817-829.
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Iweala OI, Nagler CR. The Microbiome and Food Allergy. Annu Rev Immunol. 2019 04 26; 37:377-403.
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Tan C, Mueller JL, Noviski M, Huizar J, Lau D, Dubinin A, Molofsky A, Wilson PC, Zikherman J. Nur77 Links Chronic Antigen Stimulation to B Cell Tolerance by Restricting the Survival of Self-Reactive B Cells in the Periphery. J Immunol. 2019 05 15; 202(10):2907-2923.
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MacNabb BW, Kline DE, Albright AR, Chen X, Leventhal DS, Savage PA, Kline J. Negligible Role for Deletion Mediated by cDC1 in CD8+ T Cell Tolerance. J Immunol. 2019 05 01; 202(9):2628-2635.
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Guram K, Kim SS, Wu V, Sanders PD, Patel S, Schoenberger SP, Cohen EEW, Chen SY, Sharabi AB. A Threshold Model for T-Cell Activation in the Era of Checkpoint Blockade Immunotherapy. Front Immunol. 2019; 10:491.
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Owen DL, Mahmud SA, Sjaastad LE, Williams JB, Spanier JA, Simeonov DR, Ruscher R, Huang W, Proekt I, Miller CN, Hekim C, Jeschke JC, Aggarwal P, Broeckel U, LaRue RS, Henzler CM, Alegre ML, Anderson MS, August A, Marson A, Zheng Y, Williams CB, Farrar MA. Thymic regulatory T cells arise via two distinct developmental programs. Nat Immunol. 2019 02; 20(2):195-205.
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Brown JJ, Jabri B, Dermody TS. A viral trigger for celiac disease. PLoS Pathog. 2018 09; 14(9):e1007181.
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Miller ML, McIntosh CM, Williams JB, Wang Y, Hollinger MK, Isaad NJ, Moon JJ, Gajewski TF, Chong AS, Alegre ML. Distinct Graft-Specific TCR Avidity Profiles during Acute Rejection and Tolerance. Cell Rep. 2018 08 21; 24(8):2112-2126.
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