 Immune Tolerance
"Immune Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.
| Descriptor ID |
D007108
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| MeSH Number(s) |
G12.425.746.425
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Immune Tolerance".
Below are MeSH descriptors whose meaning is more specific than "Immune Tolerance".
This graph shows the total number of publications written about "Immune Tolerance" by people in this website by year, and whether "Immune Tolerance" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1982 | 1 | 1 | 2 | | 1984 | 2 | 1 | 3 | | 1986 | 0 | 1 | 1 | | 1988 | 1 | 2 | 3 | | 1989 | 0 | 1 | 1 | | 1990 | 0 | 1 | 1 | | 1991 | 0 | 3 | 3 | | 1992 | 1 | 1 | 2 | | 1993 | 4 | 4 | 8 | | 1994 | 3 | 2 | 5 | | 1995 | 2 | 4 | 6 | | 1996 | 2 | 2 | 4 | | 1997 | 5 | 6 | 11 | | 1998 | 0 | 2 | 2 | | 1999 | 4 | 2 | 6 | | 2000 | 5 | 2 | 7 | | 2001 | 6 | 4 | 10 | | 2002 | 3 | 1 | 4 | | 2003 | 4 | 3 | 7 | | 2004 | 2 | 3 | 5 | | 2005 | 5 | 4 | 9 | | 2006 | 9 | 4 | 13 | | 2007 | 2 | 3 | 5 | | 2008 | 3 | 3 | 6 | | 2009 | 1 | 6 | 7 | | 2010 | 5 | 4 | 9 | | 2011 | 10 | 4 | 14 | | 2012 | 6 | 4 | 10 | | 2013 | 4 | 6 | 10 | | 2014 | 7 | 6 | 13 | | 2015 | 8 | 3 | 11 | | 2016 | 7 | 1 | 8 | | 2017 | 9 | 4 | 13 | | 2018 | 1 | 4 | 5 | | 2019 | 3 | 4 | 7 | | 2020 | 3 | 3 | 6 | | 2021 | 4 | 3 | 7 | | 2022 | 0 | 5 | 5 |
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Below are the most recent publications written about "Immune Tolerance" by people in Profiles.
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Wang P, Chen L, McIntosh CM, Lane JI, Li R, Xie SZ, Sattar H, Esterhazy D, Chong AS, Alegre ML. Oral alloantigen exposure promotes donor-specific tolerance in a mouse model of minor-mismatched skin transplantation. Am J Transplant. 2022 10; 22(10):2348-2359.
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Andrade MS, Young JS, Pollard JM, Yin D, Alegre ML, Chong AS. Linked sensitization by memory CD4+ T cells prevents costimulation blockade-induced transplantation tolerance. JCI Insight. 2022 06 08; 7(11).
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Pollard JM, Chong AS. Semiallogeneic Pregnancy: A Paradigm Change for T-cell Transplantation Tolerance. Transplantation. 2022 06 01; 106(6):1098-1100.
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Deak P, Knight HR, Esser-Kahn A. Robust tolerogenic dendritic cells via push/pull pairing of toll-like-receptor agonists and immunomodulators reduces EAE. Biomaterials. 2022 07; 286:121571.
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Durgam SS, Alegre ML, Chong AS. Toward an understanding of allogeneic conflict in pregnancy and transplantation. J Exp Med. 2022 05 02; 219(5).
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Maulloo CD, Cao S, Watkins EA, Raczy MM, Solanki AS, Nguyen M, Reda JW, Shim HN, Wilson DS, Swartz MA, Hubbell JA. Lymph Node-Targeted Synthetically Glycosylated Antigen Leads to Antigen-Specific Immunological Tolerance. Front Immunol. 2021; 12:714842.
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Klawon DEJ, Gilmore DC, Leonard JD, Miller CH, Chao JL, Walker MT, Duncombe RK, Tung KS, Adams EJ, Savage PA. Altered selection on a single self-ligand promotes susceptibility to organ-specific T cell infiltration. J Exp Med. 2021 06 07; 218(6).
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Miyoshi J, Miyoshi S, Delmont TO, Cham C, Lee STM, Sakatani A, Yang K, Shan Y, Kennedy M, Kiefl E, Yousef M, Crosson S, Sogin M, Antonopoulos DA, Eren AM, Leone V, Chang EB. Early-Life Microbial Restitution Reduces Colitis Risk Promoted by Antibiotic-Induced Gut Dysbiosis in Interleukin 10-/- Mice. Gastroenterology. 2021 09; 161(3):940-952.e15.
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Damo M, Wilson DS, Watkins EA, Hubbell JA. Soluble N-Acetylgalactosamine-Modified Antigens Enhance Hepatocyte-Dependent Antigen Cross-Presentation and Result in Antigen-Specific CD8+ T Cell Tolerance Development. Front Immunol. 2021; 12:555095.
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Watkins EA, Antane JT, Roberts JL, Lorentz KM, Zuerndorfer S, Dunaif AC, Bailey LJ, Tremain AC, Nguyen M, De Loera RC, Wallace RP, Weathered RK, Kontos S, Hubbell JA. Persistent antigen exposure via the eryptotic pathway drives terminal T cell dysfunction. Sci Immunol. 2021 02 26; 6(56).
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