 Insulin-Like Growth Factor I
"Insulin-Like Growth Factor I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.
| Descriptor ID |
D007334
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| MeSH Number(s) |
D12.644.276.937.400 D12.776.124.862.400 D12.776.467.937.400 D23.529.937.400
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| Concept/Terms |
Insulin-Like Growth Factor I- Insulin-Like Growth Factor I
- Insulin-Like Somatomedin Peptide I
- Insulin Like Somatomedin Peptide I
- Somatomedin C
- IGF-I-SmC
- IGF-1
- IGF-I
- Insulin Like Growth Factor I
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Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor I".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor I".
This graph shows the total number of publications written about "Insulin-Like Growth Factor I" by people in this website by year, and whether "Insulin-Like Growth Factor I" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 0 | 1 | 1 | | 1985 | 0 | 1 | 1 | | 1986 | 1 | 2 | 3 | | 1987 | 1 | 1 | 2 | | 1988 | 1 | 0 | 1 | | 1989 | 3 | 0 | 3 | | 1990 | 3 | 0 | 3 | | 1992 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1994 | 2 | 0 | 2 | | 1995 | 1 | 3 | 4 | | 1996 | 1 | 1 | 2 | | 1997 | 1 | 2 | 3 | | 1998 | 1 | 3 | 4 | | 1999 | 0 | 2 | 2 | | 2000 | 2 | 3 | 5 | | 2001 | 3 | 1 | 4 | | 2002 | 2 | 5 | 7 | | 2003 | 0 | 2 | 2 | | 2004 | 2 | 2 | 4 | | 2005 | 1 | 2 | 3 | | 2006 | 0 | 1 | 1 | | 2007 | 2 | 0 | 2 | | 2008 | 0 | 2 | 2 | | 2009 | 2 | 2 | 4 | | 2010 | 3 | 1 | 4 | | 2011 | 2 | 0 | 2 | | 2012 | 2 | 1 | 3 | | 2013 | 2 | 2 | 4 | | 2014 | 2 | 1 | 3 | | 2015 | 0 | 2 | 2 | | 2016 | 2 | 1 | 3 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Insulin-Like Growth Factor I" by people in Profiles.
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Lu J, Lu L, Yu Y, Cluette-Brown J, Martin CR, Claud EC. Effects of Intestinal Microbiota on Brain Development in Humanized Gnotobiotic Mice. Sci Rep. 2018 04 03; 8(1):5443.
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Vardar E, Larsson HM, Allazetta S, Engelhardt EM, Pinnagoda K, Vythilingam G, Hubbell JA, Lutolf MP, Frey P. Microfluidic production of bioactive fibrin micro-beads embedded in crosslinked collagen used as an injectable bulking agent for urinary incontinence treatment. Acta Biomater. 2018 02; 67:156-166.
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Grinberg YY, Zitzow LA, Kraig RP. Intranasally administered IGF-1 inhibits spreading depression in vivo. Brain Res. 2017 Dec 15; 1677:47-57.
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Deng Y, Wang Z, Zhang F, Qiao M, Yan Z, Wei Q, Wang J, Liu H, Fan J, Zou Y, Liao J, Hu X, Chen L, Yu X, Haydon RC, Luu HH, Qi H, He TC, Zhang J. A Blockade of IGF Signaling Sensitizes Human Ovarian Cancer Cells to the Anthelmintic Niclosamide-Induced Anti-Proliferative and Anticancer Activities. Cell Physiol Biochem. 2016; 39(3):871-88.
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Vardar E, Larsson HM, Engelhardt EM, Pinnagoda K, Briquez PS, Hubbell JA, Frey P. IGF-1-containing multi-layered collagen-fibrin hybrid scaffolds for bladder tissue engineering. Acta Biomater. 2016 09 01; 41:75-85.
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Carmody D, Ladsaria SS, Buikema RK, Semple RK, Greeley SA. Successful rhIGF1 treatment for over 5 years in a patient with severe insulin resistance due to homozygous insulin receptor mutation. Diabet Med. 2016 Mar; 33(3):e8-e12.
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Sargis RM, Salgia R. Multiple Endocrine Disruption by the MET/ALK Inhibitor Crizotinib in Patients With Non-small Cell Lung Cancer. Am J Clin Oncol. 2015 Oct; 38(5):442-7.
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Gonzalez AM, Hoffman JR, Jajtner AR, Townsend JR, Boone CH, Beyer KS, Baker KM, Wells AJ, Church DD, Mangine GT, Oliveira LP, Moon JR, Fukuda DH, Stout JR. Protein supplementation does not alter intramuscular anabolic signaling or endocrine response after resistance exercise in trained men. Nutr Res. 2015 Nov; 35(11):990-1000.
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Schall KA, Holoyda KA, Grant CN, Levin DE, Torres ER, Maxwell A, Pollack HA, Moats RA, Frey MR, Darehzereshki A, Al Alam D, Lien C, Grikscheit TC. Adult zebrafish intestine resection: a novel model of short bowel syndrome, adaptation, and intestinal stem cell regeneration. Am J Physiol Gastrointest Liver Physiol. 2015 Aug 01; 309(3):G135-45.
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Fragala MS, Jajtner AR, Townsend JR, Gonzalez AM, Wells AJ, Oliveira LP, Hoffman JR, Stout JR, Fukuda DH. Leukocyte IGF-1 receptor expression during muscle recovery. Med Sci Sports Exerc. 2015 Jan; 47(1):92-9.
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