 Gastric Inhibitory Polypeptide
"Gastric Inhibitory Polypeptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A gastrointestinal peptide hormone of about 43-amino acids. It is found to be a potent stimulator of INSULIN secretion and a relatively poor inhibitor of GASTRIC ACID secretion.
| Descriptor ID |
D005749
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| MeSH Number(s) |
D06.472.317.400 D06.472.699.275 D12.644.400.300 D12.644.548.275 D12.776.641.650.300
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| Concept/Terms |
Gastric Inhibitory Polypeptide- Gastric Inhibitory Polypeptide
- Inhibitory Polypeptide, Gastric
- Polypeptide, Gastric Inhibitory
- Glucose Dependent Insulinotropic Peptide
- Glucose-Dependent Insulinotropic Peptide
- Insulinotropic Peptide, Glucose-Dependent
- Peptide, Glucose-Dependent Insulinotropic
- Gastric-Inhibitory Polypeptide
- Polypeptide, Gastric-Inhibitory
- Glucose-Dependent Insulin-Releasing Peptide
- Glucose Dependent Insulin Releasing Peptide
- Insulin-Releasing Peptide, Glucose-Dependent
- Peptide, Glucose-Dependent Insulin-Releasing
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Below are MeSH descriptors whose meaning is more general than "Gastric Inhibitory Polypeptide".
Below are MeSH descriptors whose meaning is more specific than "Gastric Inhibitory Polypeptide".
This graph shows the total number of publications written about "Gastric Inhibitory Polypeptide" by people in this website by year, and whether "Gastric Inhibitory Polypeptide" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2012 | 2 | 0 | 2 | | 2014 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Gastric Inhibitory Polypeptide" by people in Profiles.
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Maekawa R, Ogata H, Murase M, Harada N, Suzuki K, Joo E, Sankoda A, Iida A, Izumoto T, Tsunekawa S, Hamada Y, Oiso Y, Inagaki N, Arima H, Hayashi Y, Seino Y. Glucose-dependent insulinotropic polypeptide is required for moderate high-fat diet- but not high-carbohydrate diet-induced weight gain. Am J Physiol Endocrinol Metab. 2018 06 01; 314(6):E572-E583.
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Iida A, Seino Y, Fukami A, Maekawa R, Yabe D, Shimizu S, Kinoshita K, Takagi Y, Izumoto T, Ogata H, Ishikawa K, Ozaki N, Tsunekawa S, Hamada Y, Oiso Y, Arima H, Hayashi Y. Endogenous GIP ameliorates impairment of insulin secretion in proglucagon-deficient mice under moderate beta cell damage induced by streptozotocin. Diabetologia. 2016 07; 59(7):1533-1541.
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Ogata H, Seino Y, Harada N, Iida A, Suzuki K, Izumoto T, Ishikawa K, Uenishi E, Ozaki N, Hayashi Y, Miki T, Inagaki N, Tsunekawa S, Hamada Y, Seino S, Oiso Y. KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state. J Endocrinol. 2014 Aug; 222(2):191-200.
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Fukami A, Seino Y, Ozaki N, Yamamoto M, Sugiyama C, Sakamoto-Miura E, Himeno T, Takagishi Y, Tsunekawa S, Ali S, Drucker DJ, Murata Y, Seino Y, Oiso Y, Hayashi Y. Ectopic expression of GIP in pancreatic ß-cells maintains enhanced insulin secretion in mice with complete absence of proglucagon-derived peptides. Diabetes. 2013 Feb; 62(2):510-8.
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Wice BM, Reeds DN, Tran HD, Crimmins DL, Patterson BW, Dunai J, Wallendorf MJ, Ladenson JH, Villareal DT, Polonsky KS. Xenin-25 amplifies GIP-mediated insulin secretion in humans with normal and impaired glucose tolerance but not type 2 diabetes. Diabetes. 2012 Jul; 61(7):1793-800.
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Wice BM, Wang S, Crimmins DL, Diggs-Andrews KA, Althage MC, Ford EL, Tran H, Ohlendorf M, Griest TA, Wang Q, Fisher SJ, Ladenson JH, Polonsky KS. Xenin-25 potentiates glucose-dependent insulinotropic polypeptide action via a novel cholinergic relay mechanism. J Biol Chem. 2010 Jun 25; 285(26):19842-53.
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Althage MC, Ford EL, Wang S, Tso P, Polonsky KS, Wice BM. Targeted ablation of glucose-dependent insulinotropic polypeptide-producing cells in transgenic mice reduces obesity and insulin resistance induced by a high fat diet. J Biol Chem. 2008 Jun 27; 283(26):18365-76.
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El-Sabbagh HN, Bloom SR, Adrian TE, Prinz RA, Baron JH, Welbourn RB. The effect of pirenzepine on meal-stimulated gastrointestinal hormones. Scand J Gastroenterol Suppl. 1980; 66:57-61.
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Kaplan EL, North PT, Norberg HP, Schulak JA, Hill BJ. Evidence for a role of the stomach in serum calcium regulation. J Surg Res. 1977 Mar; 22(3):237-41.
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