 Glutathione
"Glutathione" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
| Descriptor ID |
D005978
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| MeSH Number(s) |
D12.644.456.448
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| Concept/Terms |
Glutathione- Glutathione
- gamma-L-Glutamyl-L-Cysteinylglycine
- gamma L Glutamyl L Cysteinylglycine
- gamma-L-Glu-L-Cys-Gly
- gamma L Glu L Cys Gly
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Below are MeSH descriptors whose meaning is more general than "Glutathione".
Below are MeSH descriptors whose meaning is more specific than "Glutathione".
This graph shows the total number of publications written about "Glutathione" by people in this website by year, and whether "Glutathione" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 1 | 0 | 1 | | 1985 | 0 | 1 | 1 | | 1986 | 1 | 1 | 2 | | 1987 | 2 | 1 | 3 | | 1990 | 1 | 1 | 2 | | 1991 | 0 | 5 | 5 | | 1992 | 0 | 2 | 2 | | 1993 | 2 | 3 | 5 | | 1994 | 1 | 2 | 3 | | 1995 | 2 | 4 | 6 | | 1997 | 0 | 5 | 5 | | 1998 | 0 | 2 | 2 | | 1999 | 2 | 2 | 4 | | 2000 | 2 | 2 | 4 | | 2001 | 1 | 2 | 3 | | 2002 | 0 | 1 | 1 | | 2003 | 3 | 0 | 3 | | 2004 | 3 | 3 | 6 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 2 | 2 | | 2008 | 2 | 2 | 4 | | 2009 | 1 | 0 | 1 | | 2010 | 3 | 2 | 5 | | 2011 | 0 | 2 | 2 | | 2012 | 1 | 0 | 1 | | 2013 | 0 | 2 | 2 | | 2014 | 0 | 2 | 2 | | 2015 | 1 | 3 | 4 | | 2016 | 0 | 2 | 2 | | 2017 | 0 | 3 | 3 | | 2019 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glutathione" by people in Profiles.
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Jara O, Minogue PJ, Berthoud VM, Beyer EC. Do Connexin Mutants Cause Cataracts by Perturbing Glutathione Levels and Redox Metabolism in the Lens? Biomolecules. 2020 10 07; 10(10).
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Luengo A, Abbott KL, Davidson SM, Hosios AM, Faubert B, Chan SH, Freinkman E, Zacharias LG, Mathews TP, Clish CB, DeBerardinis RJ, Lewis CA, Vander Heiden MG. Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer. Nat Commun. 2019 12 06; 10(1):5604.
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Sayin VI, LeBoeuf SE, Singh SX, Davidson SM, Biancur D, Guzelhan BS, Alvarez SW, Wu WL, Karakousi TR, Zavitsanou AM, Ubriaco J, Muir A, Karagiannis D, Morris PJ, Thomas CJ, Possemato R, Vander Heiden MG, Papagiannakopoulos T. Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer. Elife. 2017 10 02; 6.
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Mitchell A, Tam C, Elli D, Charlton T, Osei-Owusu P, Fazlollahi F, Faull KF, Schneewind O. Glutathionylation of Yersinia pestis LcrV and Its Effects on Plague Pathogenesis. mBio. 2017 05 16; 8(3).
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Yin B, Barrionuevo G, Batinic-Haberle I, Sandberg M, Weber SG. Differences in Reperfusion-Induced Mitochondrial Oxidative Stress and Cell Death Between Hippocampal CA1 and CA3 Subfields Are Due to the Mitochondrial Thioredoxin System. Antioxid Redox Signal. 2017 Sep 20; 27(9):534-549.
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Shao D, Han J, Hou X, Fry J, Behring JB, Seta F, Long MT, Roy HK, Cohen RA, Matsui R, Bachschmid MM. Glutaredoxin-1 Deficiency Causes Fatty Liver and Dyslipidemia by Inhibiting Sirtuin-1. Antioxid Redox Signal. 2017 08 20; 27(6):313-327.
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Epel B, Sundramoorthy SV, Krzykawska-Serda M, Maggio MC, Tseytlin M, Eaton GR, Eaton SS, Rosen GM, Kao JPY, Halpern HJ. Imaging thiol redox status in murine tumors in vivo with rapid-scan electron paramagnetic resonance. J Magn Reson. 2017 Mar; 276:31-36.
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Villablanca JG, Volchenboum SL, Cho H, Kang MH, Cohn SL, Anderson CP, Marachelian A, Groshen S, Tsao-Wei D, Matthay KK, Maris JM, Hasenauer CE, Czarnecki S, Lai H, Goodarzian F, Shimada H, Reynolds CP. A Phase I New Approaches to Neuroblastoma Therapy Study of Buthionine Sulfoximine and Melphalan With Autologous Stem Cells for Recurrent/Refractory High-Risk Neuroblastoma. Pediatr Blood Cancer. 2016 08; 63(8):1349-56.
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Quan YY, Qin GQ, Huang H, Liu YH, Wang XP, Chen TS. Dominant roles of Fenton reaction in sodium nitroprusside-induced chondrocyte apoptosis. Free Radic Biol Med. 2016 05; 94:135-44.
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Lynch TL, Sivaguru M, Velayutham M, Cardounel AJ, Michels M, Barefield D, Govindan S, dos Remedios C, van der Velden J, Sadayappan S. Oxidative Stress in Dilated Cardiomyopathy Caused by MYBPC3 Mutation. Oxid Med Cell Longev. 2015; 2015:424751.
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