"Connexin 43" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 43-kDa peptide which is a member of the connexin family of gap junction proteins. Connexin 43 is a product of a gene in the alpha class of connexin genes (the alpha-1 gene). It was first isolated from mammalian heart, but is widespread in the body including the brain.
| Descriptor ID |
D018031
|
| MeSH Number(s) |
D12.776.543.585.250.200
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Connexin 43".
Below are MeSH descriptors whose meaning is more specific than "Connexin 43".
This graph shows the total number of publications written about "Connexin 43" by people in this website by year, and whether "Connexin 43" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 4 | 6 |
| 1995 | 4 | 0 | 4 |
| 1996 | 2 | 2 | 4 |
| 1997 | 5 | 0 | 5 |
| 1998 | 6 | 0 | 6 |
| 2000 | 4 | 0 | 4 |
| 2001 | 6 | 1 | 7 |
| 2002 | 2 | 1 | 3 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 3 | 4 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 2 | 2 | 4 |
| 2013 | 0 | 1 | 1 |
| 2014 | 3 | 1 | 4 |
| 2015 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Connexin 43" by people in Profiles.
-
Gap Junctions between Endothelial Cells Are Disrupted by Circulating Extracellular Vesicles from Sickle Cell Patients with Acute Chest Syndrome. Int J Mol Sci. 2020 Nov 24; 21(23).
-
ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction. Circ Res. 2020 07 03; 127(2):e28-e43.
-
Pathway of Maternal Serotonin to the Human Embryo and Fetus. Endocrinology. 2018 04 01; 159(4):1609-1629.
-
IL-1ß Inhibits Connexin 43 and Disrupts Decidualization of Human Endometrial Stromal Cells Through ERK1/2 and p38 MAP Kinase. Endocrinology. 2017 12 01; 158(12):4270-4285.
-
Intermittent hypoxia causes NOX2-dependent remodeling of atrial connexins. BMC Cell Biol. 2017 01 17; 18(Suppl 1):7.
-
LKB1 knockout mouse develops spontaneous atrial fibrillation and provides mechanistic insights into human disease process. J Am Heart Assoc. 2015 Mar 15; 4(3):e001733.
-
Connexin40 abnormalities and atrial fibrillation in the human heart. J Mol Cell Cardiol. 2014 Nov; 76:159-68.
-
Gap junction protein connexin43 exacerbates lung vascular permeability. PLoS One. 2014; 9(6):e100931.
-
Downregulation of connexin43 by microRNA-130a in cardiomyocytes results in cardiac arrhythmias. J Mol Cell Cardiol. 2014 Sep; 74:53-63.
-
c-Src kinase inhibition reduces arrhythmia inducibility and connexin43 dysregulation after myocardial infarction. J Am Coll Cardiol. 2014 Mar 11; 63(9):928-34.