"Maleimides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Derivatives of maleimide (the structural formula H2C2(CO)2NH) containing a pyrroledione ring where the hydrogen atom of the NH group is replaced with aliphatic or aromatic groups.
| Descriptor ID |
D008301
|
| MeSH Number(s) |
D02.241.081.337.502.524 D02.478.440 D03.383.129.578.399
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Maleimides".
Below are MeSH descriptors whose meaning is more specific than "Maleimides".
This graph shows the total number of publications written about "Maleimides" by people in this website by year, and whether "Maleimides" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 4 | 4 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 2 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 3 | 3 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Maleimides" by people in Profiles.
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Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays. Methods. 2021 11; 195:57-71.
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GSK-3 inhibition overcomes chemoresistance in human breast cancer. Cancer Lett. 2016 10 01; 380(2):384-392.
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An open-label phase 2 study of glycogen synthase kinase-3 inhibitor LY2090314 in patients with acute leukemia. Leuk Lymphoma. 2016 08; 57(8):1800-6.
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Destabilization of heterologous proteins mediated by the GSK3ß phosphorylation domain of the ß-catenin protein. Cell Physiol Biochem. 2013; 32(5):1187-99.
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An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity. J Med Chem. 2013 Jan 10; 56(1):254-63.
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GSK-3 promotes cell survival, growth, and PAX3 levels in human melanoma cells. Mol Cancer Res. 2012 Aug; 10(8):1065-76.
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Polyplex-microbubble hybrids for ultrasound-guided plasmid DNA delivery to solid tumors. J Control Release. 2012 Jan 30; 157(2):224-34.
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Development and characterization of immuno-nanocarriers targeting the cancer stem cell marker AC133. Int J Pharm. 2012 Feb 14; 423(1):93-101.
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Analyzing the catalytic mechanism of protein tyrosine phosphatase PtpB from Staphylococcus aureus through site-directed mutagenesis. Int J Biol Macromol. 2009 Dec 01; 45(5):463-9.
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Nanosculpting reversed wavelength sensitivity into a photoswitchable iGluR. Proc Natl Acad Sci U S A. 2009 Apr 21; 106(16):6814-9.