Mesencephalon
"Mesencephalon" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The middle of the three primitive cerebral vesicles of the embryonic brain. Without further subdivision, midbrain develops into a short, constricted portion connecting the PONS and the DIENCEPHALON. Midbrain contains two major parts, the dorsal TECTUM MESENCEPHALI and the ventral TEGMENTUM MESENCEPHALI, housing components of auditory, visual, and other sensorimoter systems.
Descriptor ID |
D008636
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MeSH Number(s) |
A08.186.211.132.659 A08.186.211.653
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mesencephalon".
Below are MeSH descriptors whose meaning is more specific than "Mesencephalon".
This graph shows the total number of publications written about "Mesencephalon" by people in this website by year, and whether "Mesencephalon" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1984 | 0 | 1 | 1 | 1985 | 0 | 2 | 2 | 1989 | 1 | 0 | 1 | 1991 | 1 | 1 | 2 | 1992 | 0 | 1 | 1 | 1995 | 1 | 2 | 3 | 1996 | 1 | 0 | 1 | 1997 | 2 | 1 | 3 | 1998 | 0 | 1 | 1 | 1999 | 1 | 1 | 2 | 2000 | 1 | 2 | 3 | 2001 | 2 | 3 | 5 | 2002 | 2 | 1 | 3 | 2003 | 1 | 1 | 2 | 2004 | 2 | 0 | 2 | 2006 | 0 | 2 | 2 | 2007 | 0 | 1 | 1 | 2008 | 1 | 1 | 2 | 2009 | 1 | 0 | 1 | 2010 | 2 | 1 | 3 | 2011 | 0 | 1 | 1 | 2012 | 3 | 0 | 3 | 2015 | 0 | 2 | 2 | 2017 | 0 | 3 | 3 | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mesencephalon" by people in Profiles.
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Liu SM, Li XZ, Zhang SN, Yang ZM, Wang KX, Lu F, Wang CZ, Yuan CS. Acanthopanax senticosus Protects Structure and Function of Mesencephalic Mitochondria in A Mouse Model of Parkinson's Disease. Chin J Integr Med. 2018 Nov; 24(11):835-843.
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Hoke KL, Hebets EA, Shizuka D. Neural Circuitry for Target Selection and Action Selection in Animal Behavior. Integr Comp Biol. 2017 10 01; 57(4):808-819.
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Burbulla LF, Song P, Mazzulli JR, Zampese E, Wong YC, Jeon S, Santos DP, Blanz J, Obermaier CD, Strojny C, Savas JN, Kiskinis E, Zhuang X, Krüger R, Surmeier DJ, Krainc D. Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease. Science. 2017 09 22; 357(6357):1255-1261.
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Covey DP, Mateo Y, Sulzer D, Cheer JF, Lovinger DM. Endocannabinoid modulation of dopamine neurotransmission. Neuropharmacology. 2017 Sep 15; 124:52-61.
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Liu G, Sgobio C, Gu X, Sun L, Lin X, Yu J, Parisiadou L, Xie C, Sastry N, Ding J, Lohr KM, Miller GW, Mateo Y, Lovinger DM, Cai H. Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression. Hum Mol Genet. 2015 Sep 15; 24(18):5299-312.
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Barrio JR, Small GW, Wong KP, Huang SC, Liu J, Merrill DA, Giza CC, Fitzsimmons RP, Omalu B, Bailes J, Kepe V. In vivo characterization of chronic traumatic encephalopathy using [F-18]FDDNP PET brain imaging. Proc Natl Acad Sci U S A. 2015 Apr 21; 112(16):E2039-47.
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Dryanovski DI, Guzman JN, Xie Z, Galteri DJ, Volpicelli-Daley LA, Lee VM, Miller RJ, Schumacker PT, Surmeier DJ. Calcium entry and a-synuclein inclusions elevate dendritic mitochondrial oxidant stress in dopaminergic neurons. J Neurosci. 2013 Jun 12; 33(24):10154-64.
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Zaki MS, Saleem SN, Dobyns WB, Barkovich AJ, Bartsch H, Dale AM, Ashtari M, Akizu N, Gleeson JG, Grijalvo-Perez AM. Diencephalic-mesencephalic junction dysplasia: a novel recessive brain malformation. Brain. 2012 Aug; 135(Pt 8):2416-27.
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Lin X, Parisiadou L, Sgobio C, Liu G, Yu J, Sun L, Shim H, Gu XL, Luo J, Long CX, Ding J, Mateo Y, Sullivan PH, Wu LG, Goldstein DS, Lovinger D, Cai H. Conditional expression of Parkinson's disease-related mutant a-synuclein in the midbrain dopaminergic neurons causes progressive neurodegeneration and degradation of transcription factor nuclear receptor related 1. J Neurosci. 2012 Jul 04; 32(27):9248-64.
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Ishak GE, Dempsey JC, Shaw DW, Tully H, Adam MP, Sanchez-Lara PA, Glass I, Rue TC, Millen KJ, Dobyns WB, Doherty D. Rhombencephalosynapsis: a hindbrain malformation associated with incomplete separation of midbrain and forebrain, hydrocephalus and a broad spectrum of severity. Brain. 2012 May; 135(Pt 5):1370-86.
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