"Mutation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
| Descriptor ID |
D009154
|
| MeSH Number(s) |
G05.365.590
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Mutation".
Below are MeSH descriptors whose meaning is more specific than "Mutation".
This graph shows the total number of publications written about "Mutation" by people in this website by year, and whether "Mutation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 15 | 26 | 41 |
| 1996 | 24 | 21 | 45 |
| 1997 | 26 | 16 | 42 |
| 1998 | 23 | 36 | 59 |
| 1999 | 14 | 34 | 48 |
| 2000 | 27 | 41 | 68 |
| 2001 | 15 | 48 | 63 |
| 2002 | 21 | 49 | 70 |
| 2003 | 19 | 76 | 95 |
| 2004 | 19 | 61 | 80 |
| 2005 | 23 | 80 | 103 |
| 2006 | 25 | 72 | 97 |
| 2007 | 27 | 56 | 83 |
| 2008 | 26 | 67 | 93 |
| 2009 | 25 | 70 | 95 |
| 2010 | 34 | 67 | 101 |
| 2011 | 35 | 83 | 118 |
| 2012 | 45 | 69 | 114 |
| 2013 | 42 | 68 | 110 |
| 2014 | 43 | 80 | 123 |
| 2015 | 47 | 90 | 137 |
| 2016 | 40 | 93 | 133 |
| 2017 | 34 | 77 | 111 |
| 2018 | 42 | 104 | 146 |
| 2019 | 49 | 70 | 119 |
| 2020 | 37 | 94 | 131 |
| 2021 | 25 | 85 | 110 |
| 2022 | 8 | 80 | 88 |
| 2023 | 2 | 84 | 86 |
| 2024 | 32 | 60 | 92 |
| 2025 | 3 | 6 | 9 |
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Below are the most recent publications written about "Mutation" by people in Profiles.
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Allele ages provide limited information about the strength of negative selection. Genetics. 2025 Mar 17; 229(3).
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A novel, rapidly progressive ataxia due to a spontaneous Myo5a mutation in mice impairs transport proteins and alters mitochondria. FASEB J. 2025 Mar 15; 39(5):e70423.
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The expanding role of the receptor tyrosine kinase MET as a therapeutic target in non-small cell lung cancer. Cell Rep Med. 2025 Mar 18; 6(3):101983.
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Proceedings of the 1st biannual bridging the gaps in lung cancer conference. Oncologist. 2025 Feb 06; 30(2).
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Protein codes promote selective subcellular compartmentalization. Science. 2025 Mar 07; 387(6738):1095-1101.
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ZNF251 haploinsufficiency confers PARP inhibitors resistance in BRCA1-mutated cancer cells through activation of homologous recombination. Cancer Lett. 2025 Mar 31; 613:217505.
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TP53 Mutations in Myeloproliferative Neoplasms: Context-Dependent Evaluation of Prognostic Relevance. Am J Hematol. 2025 Apr; 100(4):552-560.
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Functional innovation through new genes as a general evolutionary process. Nat Genet. 2025 Feb; 57(2):295-309.
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Screening a library of temperature-sensitive mutants to identify secretion factors in Staphylococcus aureus. J Bacteriol. 2025 Feb 20; 207(2):e0043324.
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Mutability and hypermutation antagonize immunoglobulin codon optimality. Mol Cell. 2025 Jan 16; 85(2):430-444.e6.