"Genomic Instability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An increased tendency of the GENOME to acquire MUTATIONS when various processes involved in maintaining and replicating the genome are dysfunctional.
| Descriptor ID |
D042822
|
| MeSH Number(s) |
C23.550.362 G05.365.590.335 G05.370
|
| Concept/Terms |
Genomic Instability- Genomic Instability
- Genomic Instabilities
- Instabilities, Genomic
- Instability, Genomic
- Genome Instability
- Genome Instabilities
- Instabilities, Genome
- Instability, Genome
Genomic Stability- Genomic Stability
- Genomic Stabilities
- Stabilities, Genomic
- Stability, Genomic
- Genome Stability
- Genome Stabilities
- Stabilities, Genome
- Stability, Genome
|
Below are MeSH descriptors whose meaning is more general than "Genomic Instability".
Below are MeSH descriptors whose meaning is more specific than "Genomic Instability".
This graph shows the total number of publications written about "Genomic Instability" by people in this website by year, and whether "Genomic Instability" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 2 | 2 |
| 2008 | 1 | 4 | 5 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 4 | 0 | 4 |
| 2014 | 1 | 2 | 3 |
| 2015 | 2 | 2 | 4 |
| 2016 | 1 | 3 | 4 |
| 2017 | 2 | 3 | 5 |
| 2018 | 0 | 2 | 2 |
| 2019 | 2 | 1 | 3 |
| 2020 | 2 | 2 | 4 |
| 2021 | 0 | 2 | 2 |
| 2022 | 2 | 1 | 3 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genomic Instability" by people in Profiles.
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Somatic loss of the Y chromosome is associated with arsenic exposure among Bangladeshi men. Int J Epidemiol. 2023 08 02; 52(4):1035-1046.
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Senataxin and RNase H2 act redundantly to suppress genome instability during class switch recombination. Elife. 2022 12 21; 11.
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Tcf-1 promotes genomic instability and T cell transformation in response to aberrant ß-catenin activation. Proc Natl Acad Sci U S A. 2022 08 09; 119(32):e2201493119.
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The role of ATXR6 expression in modulating genome stability and transposable element repression in Arabidopsis. Proc Natl Acad Sci U S A. 2022 01 18; 119(3).
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Impact of homologous recombination status and responses with veliparib combined with first-line chemotherapy in ovarian cancer in the Phase 3 VELIA/GOG-3005 study. Gynecol Oncol. 2022 02; 164(2):245-253.
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Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes. Nat Commun. 2021 11 26; 12(1):6946.
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High-resolution, ultrasensitive and quantitative DNA double-strand break labeling in eukaryotic cells using i-BLESS. Nat Protoc. 2021 02; 16(2):1034-1061.
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p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability. Nat Commun. 2020 10 06; 11(1):5007.
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Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites. Nat Commun. 2020 08 07; 11(1):3940.
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Aggressive morphologic variants of mantle cell lymphoma characterized with high genomic instability showing frequent chromothripsis, CDKN2A/B loss, and TP53 mutations: A multi-institutional study. Genes Chromosomes Cancer. 2020 08; 59(8):484-494.