"RNA Precursors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA transcripts of the DNA that are in some unfinished stage of post-transcriptional processing (RNA PROCESSING, POST-TRANSCRIPTIONAL) required for function. RNA precursors may undergo several steps of RNA SPLICING during which the phosphodiester bonds at exon-intron boundaries are cleaved and the introns are excised. Consequently a new bond is formed between the ends of the exons. Resulting mature RNAs can then be used; for example, mature mRNA (RNA, MESSENGER) is used as a template for protein production.
Descriptor ID |
D012322
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MeSH Number(s) |
D13.400.730 D13.444.735.640
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Concept/Terms |
RNA Precursor- RNA Precursor
- Precursor, RNA
- Precursor RNA
- RNA, Precursor
Primary RNA Transcript- Primary RNA Transcript
- RNA Transcript, Primary
- Transcript, Primary RNA
- Primary Transcript, RNA
- RNA Primary Transcript
- Transcript, RNA Primary
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Below are MeSH descriptors whose meaning is more general than "RNA Precursors".
Below are MeSH descriptors whose meaning is more specific than "RNA Precursors".
This graph shows the total number of publications written about "RNA Precursors" by people in this website by year, and whether "RNA Precursors" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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1993 | 1 | 0 | 1 |
1994 | 1 | 1 | 2 |
1995 | 1 | 0 | 1 |
1997 | 2 | 1 | 3 |
1998 | 2 | 0 | 2 |
1999 | 2 | 2 | 4 |
2000 | 3 | 0 | 3 |
2001 | 2 | 0 | 2 |
2002 | 1 | 0 | 1 |
2004 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2006 | 1 | 1 | 2 |
2007 | 1 | 0 | 1 |
2008 | 0 | 2 | 2 |
2009 | 2 | 2 | 4 |
2010 | 1 | 2 | 3 |
2013 | 2 | 1 | 3 |
2015 | 1 | 0 | 1 |
2016 | 2 | 1 | 3 |
2017 | 1 | 1 | 2 |
2019 | 1 | 1 | 2 |
2020 | 1 | 1 | 2 |
2021 | 1 | 0 | 1 |
2022 | 1 | 1 | 2 |
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Below are the most recent publications written about "RNA Precursors" by people in Profiles.
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m6A modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5' splice site. Elife. 2022 11 21; 11.
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Recent insights into the structure, function, and regulation of the eukaryotic transfer RNA splicing endonuclease complex. Wiley Interdiscip Rev RNA. 2022 09; 13(5):e1717.
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psiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation. Nat Commun. 2021 03 05; 12(1):1488.
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Reconstitution of the human tRNA splicing endonuclease complex: insight into the regulation of pre-tRNA cleavage. Nucleic Acids Res. 2020 08 20; 48(14):7609-7622.
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Cryo-EM snapshots of the human spliceosome reveal structural adaptions for splicing regulation. Curr Opin Struct Biol. 2020 12; 65:139-148.
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Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG. Mol Cell. 2019 10 03; 76(1):70-81.e9.
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A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation. Science. 2019 02 15; 363(6428):710-714.
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Our views of dynamic N6-methyladenosine RNA methylation. RNA. 2018 03; 24(3):268-272.
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Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection. Science. 2017 12 08; 358(6368):1283-1288.
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A druggable target for rescuing microRNA defects. Bioorg Med Chem Lett. 2016 10 15; 26(20):4942-4946.