"RNA Precursors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA transcripts of the DNA that are in some unfinished stage of post-transcriptional processing (RNA PROCESSING, POST-TRANSCRIPTIONAL) required for function. RNA precursors may undergo several steps of RNA SPLICING during which the phosphodiester bonds at exon-intron boundaries are cleaved and the introns are excised. Consequently a new bond is formed between the ends of the exons. Resulting mature RNAs can then be used; for example, mature mRNA (RNA, MESSENGER) is used as a template for protein production.
Descriptor ID |
D012322
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MeSH Number(s) |
D13.400.730 D13.444.735.640
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Concept/Terms |
RNA Precursor- RNA Precursor
- Precursor, RNA
- Precursor RNA
- RNA, Precursor
Primary RNA Transcript- Primary RNA Transcript
- RNA Transcript, Primary
- Transcript, Primary RNA
- Primary Transcript, RNA
- RNA Primary Transcript
- Transcript, RNA Primary
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Below are MeSH descriptors whose meaning is more general than "RNA Precursors".
Below are MeSH descriptors whose meaning is more specific than "RNA Precursors".
This graph shows the total number of publications written about "RNA Precursors" by people in this website by year, and whether "RNA Precursors" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 |
1997 | 2 | 1 | 3 |
1998 | 2 | 0 | 2 |
1999 | 2 | 2 | 4 |
2000 | 3 | 0 | 3 |
2001 | 2 | 0 | 2 |
2002 | 1 | 0 | 1 |
2004 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2006 | 1 | 1 | 2 |
2007 | 1 | 0 | 1 |
2008 | 0 | 2 | 2 |
2009 | 2 | 2 | 4 |
2010 | 1 | 2 | 3 |
2013 | 2 | 1 | 3 |
2015 | 1 | 0 | 1 |
2016 | 2 | 1 | 3 |
2017 | 1 | 1 | 2 |
2019 | 2 | 1 | 3 |
2020 | 1 | 1 | 2 |
2021 | 2 | 0 | 2 |
2022 | 1 | 1 | 2 |
2023 | 3 | 1 | 4 |
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Below are the most recent publications written about "RNA Precursors" by people in Profiles.
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Inter-species association mapping links splice site evolution to METTL16 and SNRNP27K. Elife. 2023 10 03; 12.
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Base-resolution quantitative DAMM-seq for mapping RNA methylations in tRNA and mitochondrial polycistronic RNA. Methods Enzymol. 2023; 692:39-54.
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New insights into RNA processing by the eukaryotic tRNA splicing endonuclease. J Biol Chem. 2023 09; 299(9):105138.
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Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex. Nat Struct Mol Biol. 2023 06; 30(6):824-833.
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m6A modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5' splice site. Elife. 2022 11 21; 11.
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Recent insights into the structure, function, and regulation of the eukaryotic transfer RNA splicing endonuclease complex. Wiley Interdiscip Rev RNA. 2022 09; 13(5):e1717.
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Recognition of single-stranded nucleic acids by small-molecule splicing modulators. Nucleic Acids Res. 2021 08 20; 49(14):7870-7883.
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psiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation. Nat Commun. 2021 03 05; 12(1):1488.
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Reconstitution of the human tRNA splicing endonuclease complex: insight into the regulation of pre-tRNA cleavage. Nucleic Acids Res. 2020 08 20; 48(14):7609-7622.
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Cryo-EM snapshots of the human spliceosome reveal structural adaptions for splicing regulation. Curr Opin Struct Biol. 2020 12; 65:139-148.