 Paraproteins
"Paraproteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Abnormal immunoglobulins synthesized by atypical cells of the MONONUCLEAR PHAGOCYTE SYSTEM. Paraproteins containing only light chains lead to Bence Jones paraproteinemia, while the presence of only atypical heavy chains leads to heavy chain disease. Most of the paraproteins show themselves as an M-component (monoclonal gammopathy) in electrophoresis. Diclonal and polyclonal paraproteins are much less frequently encountered.
| Descriptor ID |
D010266
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| MeSH Number(s) |
D12.776.124.486.485.900 D12.776.124.790.651.900 D12.776.377.715.548.900
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Paraproteins".
Below are MeSH descriptors whose meaning is more specific than "Paraproteins".
This graph shows the total number of publications written about "Paraproteins" by people in this website by year, and whether "Paraproteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1982 | 1 | 0 | 1 | | 1983 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Paraproteins" by people in Profiles.
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Wei X, Calvo-Vidal MN, Chen S, Wu G, Revuelta MV, Sun J, Zhang J, Walsh MF, Nichols KE, Joseph V, Snyder C, Vachon CM, McKay JD, Wang SP, Jayabalan DS, Jacobs LM, Becirovic D, Waller RG, Artomov M, Viale A, Patel J, Phillip J, Chen-Kiang S, Curtin K, Salama M, Atanackovic D, Niesvizky R, Landgren O, Slager SL, Godley LA, Churpek J, Garber JE, Anderson KC, Daly MJ, Roeder RG, Dumontet C, Lynch HT, Mullighan CG, Camp NJ, Offit K, Klein RJ, Yu H, Cerchietti L, Lipkin SM. Germline Lysine-Specific Demethylase 1 (LSD1/KDM1A) Mutations Confer Susceptibility to Multiple Myeloma. Cancer Res. 2018 05 15; 78(10):2747-2759.
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Austin GE, Check IJ, Hunter RL. Analysis of the reliability of serial paraprotein determinations in patients with plasma cell dyscrasias. Am J Clin Pathol. 1983 Feb; 79(2):227-30.
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Fingerle RE, Check IJ. Diclonal gammopathy in chronic cold agglutinin disease. Am J Clin Pathol. 1982 Dec; 78(6):867-70.
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