 Penicillins
"Penicillins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065)
| Descriptor ID |
D010406
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| MeSH Number(s) |
D02.065.589.099.750 D02.886.108.750 D03.438.260.825 D03.605.084.737 D04.075.080.875.099.221.750
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| Concept/Terms |
Penicillins- Penicillins
- Antibiotics, Penicillin
- Penicillin Antibiotics
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Below are MeSH descriptors whose meaning is more general than "Penicillins".
Below are MeSH descriptors whose meaning is more specific than "Penicillins".
This graph shows the total number of publications written about "Penicillins" by people in this website by year, and whether "Penicillins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 0 | 1 | | 1981 | 1 | 0 | 1 | | 1983 | 1 | 0 | 1 | | 1984 | 1 | 2 | 3 | | 1986 | 0 | 1 | 1 | | 1988 | 2 | 0 | 2 | | 1992 | 0 | 1 | 1 | | 1994 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 3 | 3 | | 1999 | 1 | 0 | 1 | | 2001 | 2 | 0 | 2 | | 2002 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2016 | 2 | 0 | 2 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Penicillins" by people in Profiles.
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Sobotka SA, Ross LF. 50 Years Ago in TheJournal ofPediatrics: Why Patients Don't Follow Medical Advice: A Study of Children on Long-Term Antistreptococcal Prophylaxis. J Pediatr. 2019 12; 215:63.
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Sato H, Zhang LS, Martinez K, Chang EB, Yang Q, Wang F, Howles PN, Hokari R, Miura S, Tso P. Antibiotics Suppress Activation of Intestinal Mucosal Mast Cells and Reduce Dietary Lipid Absorption in Sprague-Dawley Rats. Gastroenterology. 2016 11; 151(5):923-932.
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Shah NS, Ridgway JP, Pettit N, Fahrenbach J, Robicsek A. Documenting Penicillin Allergy: The Impact of Inconsistency. PLoS One. 2016; 11(3):e0150514.
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Peterson LR. Penicillins for treatment of pneumococcal pneumonia: does in vitro resistance really matter? Clin Infect Dis. 2006 Jan 15; 42(2):224-33.
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Undey C, Tatara E, Cinar A. Intelligent real-time performance monitoring and quality prediction for batch/fed-batch cultivations. J Biotechnol. 2004 Feb 19; 108(1):61-77.
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Boyle-Vavra S, Yin S, Challapalli M, Daum RS. Transcriptional induction of the penicillin-binding protein 2 gene in Staphylococcus aureus by cell wall-active antibiotics oxacillin and vancomycin. Antimicrob Agents Chemother. 2003 Mar; 47(3):1028-36.
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Hussain FM, Boyle-Vavra S, Shete PB, Daum RS. Evidence for a continuum of decreased vancomycin susceptibility in unselected Staphylococcus aureus clinical isolates. J Infect Dis. 2002 Sep 01; 186(5):661-7.
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Birol G, Undey C, Parulekar SJ, Cinar A. A morphologically structured model for penicillin production. Biotechnol Bioeng. 2002 Mar 05; 77(5):538-52.
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Kaplan EL, Johnson DR. Unexplained reduced microbiological efficacy of intramuscular benzathine penicillin G and of oral penicillin V in eradication of group a streptococci from children with acute pharyngitis. Pediatrics. 2001 Nov; 108(5):1180-6.
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Fowler VG, Maxwell GL, Myers SA, Shea CR, Livengood CN, Prieto VG, Hicks CB. Failure of benzathine penicillin in a case of seronegative secondary syphilis in a patient with acquired immunodeficiency syndrome: case report and review of the literature. Arch Dermatol. 2001 Oct; 137(10):1374-6.
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