 Rec A Recombinases
"Rec A Recombinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of recombinases initially identified in BACTERIA. They catalyze the ATP-driven exchange of DNA strands in GENETIC RECOMBINATION. The product of the reaction consists of a duplex and a displaced single-stranded loop, which has the shape of the letter D and is therefore called a D-loop structure.
| Descriptor ID |
D011938
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| MeSH Number(s) |
D08.811.739.650 D08.811.913.696.445.692
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Rec A Recombinases".
Below are MeSH descriptors whose meaning is more specific than "Rec A Recombinases".
This graph shows the total number of publications written about "Rec A Recombinases" by people in this website by year, and whether "Rec A Recombinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 1 | 1 | | 1994 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Rec A Recombinases" by people in Profiles.
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Gataulin DV, Carey JN, Li J, Shah P, Grubb JT, Bishop DK. The ATPase activity of E. coli RecA prevents accumulation of toxic complexes formed by erroneous binding to undamaged double stranded DNA. Nucleic Acids Res. 2018 10 12; 46(18):9510-9523.
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Brown MS, Bishop DK. DNA strand exchange and RecA homologs in meiosis. Cold Spring Harb Perspect Biol. 2014 Dec 04; 7(1):a016659.
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Budke B, Chan YL, Bishop DK, Connell PP. Real-time solution measurement of RAD51- and RecA-mediated strand assimilation without background annealing. Nucleic Acids Res. 2013 Jul; 41(13):e130.
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Danilowicz C, Feinstein E, Conover A, Coljee VW, Vlassakis J, Chan YL, Bishop DK, Prentiss M. RecA homology search is promoted by mechanical stress along the scanned duplex DNA. Nucleic Acids Res. 2012 Feb; 40(4):1717-27.
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Zhang AP, Pigli YZ, Rice PA. Structure of the LexA-DNA complex and implications for SOS box measurement. Nature. 2010 Aug 12; 466(7308):883-6.
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Budke B, Kuzminov A. Production of clastogenic DNA precursors by the nucleotide metabolism in Escherichia coli. Mol Microbiol. 2010 Jan; 75(1):230-45.
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Conway AB, Lynch TW, Zhang Y, Fortin GS, Fung CW, Symington LS, Rice PA. Crystal structure of a Rad51 filament. Nat Struct Mol Biol. 2004 Aug; 11(8):791-6.
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VanLoock MS, Yu X, Yang S, Galkin VE, Huang H, Rajan SS, Anderson WF, Stohl EA, Seifert HS, Egelman EH. Complexes of RecA with LexA and RecX differentiate between active and inactive RecA nucleoprotein filaments. J Mol Biol. 2003 Oct 17; 333(2):345-54.
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Gasior SL, Olivares H, Ear U, Hari DM, Weichselbaum R, Bishop DK. Assembly of RecA-like recombinases: distinct roles for mediator proteins in mitosis and meiosis. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8411-8.
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Bishop DK. RecA homologs Dmc1 and Rad51 interact to form multiple nuclear complexes prior to meiotic chromosome synapsis. Cell. 1994 Dec 16; 79(6):1081-92.
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