"Transposases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that recombine DNA segments by a process which involves the formation of a synapse between two DNA helices, the cleavage of single strands from each DNA helix and the ligation of a DNA strand from one DNA helix to the other. The resulting DNA structure is called a Holliday junction which can be resolved by DNA REPLICATION or by HOLLIDAY JUNCTION RESOLVASES.
| Descriptor ID |
D019895
|
| MeSH Number(s) |
D08.811.739.500.667 D08.811.913.696.445.825
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Transposases".
Below are MeSH descriptors whose meaning is more specific than "Transposases".
This graph shows the total number of publications written about "Transposases" by people in this website by year, and whether "Transposases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Transposases" by people in Profiles.
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Structure of TnsABCD transpososome reveals mechanisms of targeted DNA transposition. Cell. 2024 Nov 27; 187(24):6865-6881.e16.
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Quantitative analysis of cis-regulatory elements in transcription with KAS-ATAC-seq. Nat Commun. 2024 Aug 10; 15(1):6852.
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Structural basis for topological regulation of Tn3 resolvase. Nucleic Acids Res. 2023 02 22; 51(3):1001-1018.
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Comment on "RNA-guided DNA insertion with CRISPR-associated transposases". Science. 2020 06 05; 368(6495).
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Structure of the P element transpososome reveals new twists on the DD(E/D) theme. Nat Struct Mol Biol. 2019 11; 26(11):989-990.
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Mu transpososome activity-profiling yields hyperactive MuA variants for highly efficient genetic and genome engineering. Nucleic Acids Res. 2018 05 18; 46(9):4649-4661.
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Target DNA bending by the Mu transpososome promotes careful transposition and prevents its reversal. Elife. 2017 02 13; 6.
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Mobile genetic elements: in silico, in vitro, in vivo. Mol Ecol. 2016 Mar; 25(5):1027-31.
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The ยต transpososome structure sheds light on DDE recombinase evolution. Nature. 2012 Nov 15; 491(7424):413-7.
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Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor. Nat Genet. 2011 Mar 20; 43(4):379-86.