 Vasoactive Intestinal Peptide
"Vasoactive Intestinal Peptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly basic, 28 amino acid neuropeptide released from intestinal mucosa. It has a wide range of biological actions affecting the cardiovascular, gastrointestinal, and respiratory systems and is neuroprotective. It binds special receptors (RECEPTORS, VASOACTIVE INTESTINAL PEPTIDE).
| Descriptor ID |
D014660
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| MeSH Number(s) |
D06.472.317.950 D06.472.699.952 D12.644.400.875 D12.644.548.952 D12.776.641.650.875
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| Concept/Terms |
Vasoactive Intestinal Peptide- Vasoactive Intestinal Peptide
- Intestinal Peptide, Vasoactive
- Peptide, Vasoactive Intestinal
- Vasoactive Intestinal Polypeptide
- Intestinal Polypeptide, Vasoactive
- Polypeptide, Vasoactive Intestinal
- VIP (Vasoactive Intestinal Peptide)
- Vasointestinal Peptide
- Peptide, Vasointestinal
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Below are MeSH descriptors whose meaning is more general than "Vasoactive Intestinal Peptide".
Below are MeSH descriptors whose meaning is more specific than "Vasoactive Intestinal Peptide".
This graph shows the total number of publications written about "Vasoactive Intestinal Peptide" by people in this website by year, and whether "Vasoactive Intestinal Peptide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1983 | 1 | 1 | 2 | | 1985 | 1 | 1 | 2 | | 1990 | 0 | 1 | 1 | | 1992 | 0 | 1 | 1 | | 1995 | 1 | 0 | 1 | | 1996 | 1 | 1 | 2 | | 1998 | 0 | 2 | 2 | | 2006 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Vasoactive Intestinal Peptide" by people in Profiles.
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Lythgoe MP, Rhodes CJ, Ghataorhe P, Attard M, Wharton J, Wilkins MR. Why drugs fail in clinical trials in pulmonary arterial hypertension, and strategies to succeed in the future. Pharmacol Ther. 2016 08; 164:195-203.
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Kapoor R, Moseley RH, Kapoor JR, Crapo LM, Saint S. Clinical problem-solving. Needle in a haystack. N Engl J Med. 2009 Feb 05; 360(6):616-21.
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Rhodes CJ, Davidson A, Gibbs JS, Wharton J, Wilkins MR. Therapeutic targets in pulmonary arterial hypertension. Pharmacol Ther. 2009 Jan; 121(1):69-88.
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Olopade CO, Yu J, Abubaker J, Mensah E, Paul S. Catalytic hydrolysis of VIP in pregnant women with asthma. J Asthma. 2006 Aug; 43(6):429-32.
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McCool BA, Pin JP, Harpold MM, Brust PF, Stauderman KA, Lovinger DM. Rat group I metabotropic glutamate receptors inhibit neuronal Ca2+ channels via multiple signal transduction pathways in HEK 293 cells. J Neurophysiol. 1998 Jan; 79(1):379-91.
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Hatipoglu U, Gao X, Verral S, Séjourné F, Pitrak D, Alkan-Onyüksel H, Rubinstein I. Sterically stabilized phospholipids attenuate human neutrophils chemotaxis in vitro. Life Sci. 1998; 63(8):693-9.
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Suzuki H, Gao XP, Olopade CO, Rubinstein I. Neutral endopeptidase modulates VIP-induced vasodilation in hamster cheek pouch vessels in situ. Am J Physiol. 1996 Aug; 271(2 Pt 2):R393-7.
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Gabriel SM, Davidson M, Haroutunian V, Powchik P, Bierer LM, Purohit DP, Perl DP, Davis KL. Neuropeptide deficits in schizophrenia vs. Alzheimer's disease cerebral cortex. Biol Psychiatry. 1996 Jan 15; 39(2):82-91.
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Gao XP, Jaffe HA, Olopade CO, Rubinstein I. Stable VIP analogue Ro-24-9981 potentiates substance P-induced plasma exudation in hamster cheek pouch. J Appl Physiol (1985). 1995 Sep; 79(3):968-74.
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Ciancio MJ, Vitiritti L, Dhar A, Chang EB. Endotoxin-induced alterations in rat colonic water and electrolyte transport. Gastroenterology. 1992 Nov; 103(5):1437-43.
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