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Ayman Al-Hendy

InstitutionUniversity of Chicago
DepartmentObstetrics and Gynecology
AddressChicago IL 60637
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    R01HD106285     (AL-HENDY, AYMAN ;BOYER, THOMAS G)Aug 9, 2021 - May 31, 2026
    Pathological reprogramming of the m6A epitranscriptome in uterine fibroids
    Role: Co-Principal Investigator

    R01HD100367     (AL-HENDY, AYMAN ;GONZALEZ, FRANK)Sep 26, 2019 - Aug 31, 2024
    3/4, University of Illinois at Chicago Clinical Site- Reproductive Medicine Collaborative Consortium: A randomized placebo-controlled trial of EGCG to improve fertility in women with uterine fibroids
    Role: Co-Principal Investigator

    R01HD094378     (AL-HENDY, AYMAN ;BOYER, THOMAS G)Feb 15, 2018 - Jul 31, 2023
    Hypovitaminosis D promotes MED12-associated genomic instability in uterine fibroids
    Role: Co-Principal Investigator

    R01ES028615     (AL-HENDY, AYMAN)Sep 15, 2017 - Jul 31, 2023
    Gene X Environment Interactions in the Pathogenesis of Uterine Fibroids
    Role: Principal Investigator

    U54RR026140     (ADUNYAH, SAMUEL)Sep 25, 2009 - Jun 30, 2014
    Meharry Clinical and Translational Research Center (MeTRC)
    Role: Co-Principal Investigator

    R21HD046639     (AL-HENDY, AYMAN)May 5, 2005 - Apr 30, 2008
    Reversal of Infertility in Ovarian Failure
    Role: Principal Investigator

    R01HD046228     (AL-HENDY, AYMAN)Sep 24, 2003 - Feb 29, 2016
    Targeting Adenovirus for Gene Therapy of Uterine Leiomyoma
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Al-Hendy A, Lukes AS, Venturella R, Villarroel C, McKain L, Li Y, Wagman RB, Stewart EA. A plain language summary of the long-term relugolix combination therapy study for uterine fibroids. J Comp Eff Res. 2023 08; 12(8):e230069. PMID: 37477173.
      Citations:    Fields:    Translation:Humans
    2. Yang Q, Ali M, Treviño LS, Mas A, Ismail N, Al-Hendy A. Epigenetic Modulation of Inflammatory Pathways in Myometrial Stem Cells and Risk of Uterine Fibroids. Int J Mol Sci. 2023 Jul 19; 24(14). PMID: 37511399; PMCID: PMC10380326.
      Citations:    Fields:    Translation:HumansCells
    3. Al-Hendy A, Zhou YF, Faustmann T, Groettrup-Wolfers E, Laapas K, Parke S, Seitz C, Al-Hendy A, Zhou YF, Faustmann T, Groettrup-Wolfers E, Laapas K, Parke S, Seitz C. Efficacy and safety of vilaprisan in women with uterine fibroids: data from the ASTEROID 3 randomized controlled trial. F S Sci. 2023 Jul 10. PMID: 37437885.
      Citations:    Fields:    
    4. Park HS, Cetin E, Siblini H, Seok J, Alkelani H, Alkhrait S, Liakath Ali F, Mousaei Ghasroldasht M, Beckman A, Al-Hendy A. Therapeutic Potential of Mesenchymal Stem Cell-Derived Extracellular Vesicles to Treat PCOS. Int J Mol Sci. 2023 Jul 06; 24(13). PMID: 37446328; PMCID: PMC10342552.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    5. Park HS, Chugh RM, Seok J, Cetin E, Mohammed H, Siblini H, Liakath Ali F, Ghasroldasht MM, Alkelani H, Elsharoud A, Ulin M, Esfandyari S, Al-Hendy A. Comparison of the therapeutic effects between stem cells and exosomes in primary ovarian insufficiency: as promising as cells but different persistency and dosage. Stem Cell Res Ther. 2023 06 20; 14(1):165. PMID: 37340468; PMCID: PMC10283237.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    6. Bariani MV, Cui YH, Ali M, Bai T, Grimm SL, Coarfa C, Walker CL, He YY, Yang Q, Al-Hendy A, Bariani MV, Cui YH, Ali M, Bai T, Grimm SL, Coarfa C, Walker CL, He YY, Yang Q, Al-Hendy A. TGFß signaling links early-life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells. Res Sq. 2023 Jun 07. PMID: 37333266; PMCID: PMC10274956.
    7. Al-Hendy A, Lukes AS, Poindexter AN, Venturella R, Villarroel C, Critchley HO, Li Y, McKain L, Arjona Ferreira JC, Langenberg AG, Wagman RB, Stewart EA. A plain language summary of the safety of relugolix combination therapy and improvement in symptoms in women with uterine fibroids from the LIBERTY 1 and LIBERTY 2 studies. Pain Manag. 2023 Apr; 13(4):205-211. PMID: 37183454.
      Citations:    Fields:    Translation:Humans
    8. Ali M, Stone D, Laknaur A, Yang Q, Al-Hendy A, Ali M, Stone D, Laknaur A, Yang Q, Al-Hendy A. EZH2 activates Wnt/ß-catenin signaling in human uterine fibroids, which is inhibited by the natural compound methyl jasmonate. F S Sci. 2023 08; 4(3):239-256. PMID: 37182601.
      Citations:    Fields:    Translation:HumansCells
    9. Yang Q, Al-Hendy A. The Functional Role and Regulatory Mechanism of FTO m6A RNA Demethylase in Human Uterine Leiomyosarcoma. Int J Mol Sci. 2023 Apr 27; 24(9). PMID: 37175660; PMCID: PMC10178470.
      Citations:    Fields:    Translation:HumansCells
    10. Ali M, Ciebiera M, Vafaei S, Alkhrait S, Chen HY, Chiang YF, Huang KC, Feduniw S, Hsia SM, Al-Hendy A. Progesterone Signaling and Uterine Fibroid Pathogenesis; Molecular Mechanisms and Potential Therapeutics. Cells. 2023 04 09; 12(8). PMID: 37190026; PMCID: PMC10136461.
      Citations: 2     Fields:    Translation:Humans
    11. Yang Q, Al-Hendy A. Update on the Role and Regulatory Mechanism of Extracellular Matrix in the Pathogenesis of Uterine Fibroids. Int J Mol Sci. 2023 Mar 17; 24(6). PMID: 36982852; PMCID: PMC10051203.
      Citations: 2     Fields:    Translation:HumansCells
    12. Al-Hendy A, Yang Q, Dos Anjos LG, de Almeida BC, Baracat EC, Carvalho KC. Gene Expression Profile of Uterine Leiomyoma from Women Exposed to Different Air Pollution Levels in Metropolitan Cities of Sao Paulo, Brazil. Int J Mol Sci. 2023 Jan 26; 24(3). PMID: 36768749; PMCID: PMC9917088.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    13. Sefah N, Ndebele S, Prince L, Korasare E, Agbleke M, Nkansah A, Thompson H, Al-Hendy A, Agbleke AA. Uterine fibroids - Causes, impact, treatment, and lens to the African perspective. Front Pharmacol. 2022; 13:1045783. PMID: 36703761; PMCID: PMC9871264.
      Citations: 2     
    14. Siblini H, Al-Hendy A, Segars J, Taylor HS, Singh B, Flaminia A, Flores VA, Christman GM, Huang H, Johnson JJ, Zhang H, González F. Assessing the Hepatic Safety of Epigallocatechin Gallate (EGCG) in Reproductive-Aged Women. Nutrients. 2023 Jan 09; 15(2). PMID: 36678191; PMCID: PMC9861948.
      Citations: 7     Fields:    Translation:Humans
    15. Elkafas H, Wall M, Al-Hendy A, Ismail N, Walls M. Gut and genital tract microbiomes: Dysbiosis and link to gynecological disorders. Front Cell Infect Microbiol. 2022; 12:1059825. PMID: 36590579; PMCID: PMC9800796.
      Citations: 3     Fields:    Translation:Humans
    16. Yang Q, Falahati A, Khosh A, Mohammed H, Kang W, Bariani MV, Boyer TG, Al-Hendy A, Corachán A. Targeting Class I Histone Deacetylases in Human Uterine Leiomyosarcoma. Cells. 2022 Nov 27; 11(23). PMID: 36497061; PMCID: PMC9735512.
      Citations: 2     Fields:    Translation:Humans
    17. Madueke-Laveaux OS, Ciebiera M, Al-Hendy A. GnRH analogs for the treatment of heavy menstrual bleeding associated with uterine fibroids. F S Rep. 2023 Jun; 4(2 Suppl):46-50. PMID: 37223760; PMCID: PMC10201292.
    18. Stewart EA, Lukes AS, Venturella R, Li Y, Hunsche E, Wagman RB, Al-Hendy A. Quality of life with relugolix combination therapy for uterine fibroids: LIBERTY randomized trials. Am J Obstet Gynecol. 2023 03; 228(3):320.e1-320.e11. PMID: 36370871.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    19. Al-Hendy A, Lukes AS, Poindexter AN, Venturella R, Villarroel C, McKain L, Li Y, Wagman RB, Stewart EA. Long-term Relugolix Combination Therapy for Symptomatic Uterine Leiomyomas. Obstet Gynecol. 2022 Dec 01; 140(6):920-930. PMID: 36357960; PMCID: PMC9665945.
      Citations: 3     Fields:    Translation:Humans
    20. Dobroff AS, Yang Q, Al-Hendy A, de Almeida BC, Dos Anjos LG, Baracat EC, Carvalho KC. Epigenetic Features in Uterine Leiomyosarcoma and Endometrial Stromal Sarcomas: An Overview of the Literature. Biomedicines. 2022 Oct 13; 10(10). PMID: 36289829; PMCID: PMC9599831.
      Citations: 3     
    21. Taylor HS, Stewart EA, Bradley L, Marsh E, Archer D, Al-Hendy A, Petraglia F, Watts N, Gotteland JP, Bestel E, Terrill P, Loumaye E, Humberstone A, Garner E, Donnez J. Linzagolix with and without hormonal add-back therapy for the treatment of symptomatic uterine fibroids: two randomised, placebo-controlled, phase 3 trials. Lancet. 2022 09 17; 400(10356):896-907. PMID: 36116480.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    22. Yang Q, Ciebiera M, Bariani MV, Ali M, Elkafas H, Boyer TG, Al-Hendy A. Comprehensive Review of Uterine Fibroids: Developmental Origin, Pathogenesis, and Treatment. Endocr Rev. 2022 07 13; 43(4):678-719. PMID: 34741454; PMCID: PMC9277653.
      Citations: 32     Fields:    Translation:Humans
    23. Yang Q, Bariani MV, Falahati A, Khosh A, Lastra RR, Siblini H, Boyer TG, Al-Hendy A. The Functional Role and Regulatory Mechanism of Bromodomain-Containing Protein 9 in Human Uterine Leiomyosarcoma. Cells. 2022 07 10; 11(14). PMID: 35883603; PMCID: PMC9323884.
      Citations: 4     Fields:    Translation:Humans
    24. Banerjee S, Xu W, Chowdhury I, Driss A, Ali M, Yang Q, Al-Hendy A, Thompson WE. Human Myometrial and Uterine Fibroid Stem Cell-Derived Organoids for Intervening the Pathophysiology of Uterine Fibroid. Reprod Sci. 2022 09; 29(9):2607-2619. PMID: 35585291; PMCID: PMC9444830.
      Citations: 3     Fields:    Translation:HumansCells
    25. Navarro A, Bariani MV, Park HS, Zota AR, Al-Hendy A. Report of Exosomes Isolated from a Human Uterine Leiomyoma Cell Line and Their Impact on Endometrial Vascular Endothelial Cells. Pharmaceuticals (Basel). 2022 May 05; 15(5). PMID: 35631403; PMCID: PMC9143402.
    26. Stewart EA, Lukes AS, Venturella R, Arjona Ferreira JC, Li Y, Hunsche E, Wagman RB, Al-Hendy A. Relugolix Combination Therapy for Uterine Leiomyoma-Associated Pain in the LIBERTY Randomized Trials. Obstet Gynecol. 2022 06 01; 139(6):1070-1081. PMID: 35675604.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    27. Zota AR, Chu MT, Marfori CQ, Khati NJ, Al-Hendy A, Taggart T. Adverse childhood experiences and health-related quality of life among women undergoing hysterectomy for uterine leiomyoma. Am J Obstet Gynecol. 2022 08; 227(2):351-353.e5. PMID: 35461825; PMCID: PMC10401515.
      Citations: 1     Fields:    Translation:Humans
    28. Park HS, Chugh RM, Pergande MR, Cetin E, Siblini H, Esfandyari S, Cologna SM, Al-Hendy A. Non-Cytokine Protein Profile of the Mesenchymal Stem Cell Secretome That Regulates the Androgen Production Pathway. Int J Mol Sci. 2022 Apr 22; 23(9). PMID: 35563028; PMCID: PMC9101816.
      Citations: 4     Fields:    Translation:HumansCells
    29. Yang Q, Al-Hendy A. The Regulatory Functions and the Mechanisms of Long Non-Coding RNAs in Cervical Cancer. Cells. 2022 03 29; 11(7). PMID: 35406713; PMCID: PMC8998012.
      Citations: 9     Fields:    Translation:Humans
    30. Mousaei Ghasroldasht M, Seok J, Park HS, Liakath Ali FB, Al-Hendy A. Stem Cell Therapy: From Idea to Clinical Practice. Int J Mol Sci. 2022 Mar 05; 23(5). PMID: 35269990; PMCID: PMC8911494.
      Citations: 18     Fields:    Translation:Humans
    31. Fadel HE, Al-Hendy A. Development of Obstetric Practice During the Early Islamic Era. Reprod Sci. 2022 09; 29(9):2587-2592. PMID: 35233736; PMCID: PMC9444839.
      Citations:    Fields:    Translation:Humans
    32. Wlodarczyk M, Nowicka G, Ciebiera M, Ali M, Yang Q, Al-Hendy A. Epigenetic Regulation in Uterine Fibroids-The Role of Ten-Eleven Translocation Enzymes and Their Potential Therapeutic Application. Int J Mol Sci. 2022 Feb 28; 23(5). PMID: 35269864; PMCID: PMC8910916.
      Citations:    Fields:    Translation:HumansCells
    33. Leyland N, Leonardi M, Murji A, Singh SS, Al-Hendy A, Bradley L. A Call-to-Action for Clinicians to Implement Evidence-Based Best Practices When Caring for Women with Uterine Fibroids. Reprod Sci. 2022 04; 29(4):1188-1196. PMID: 35178678; PMCID: PMC8853611.
      Citations: 2     Fields:    Translation:Humans
    34. Afrin S, Ali M, El Sabeh M, Yang Q, Al-Hendy A, Borahay MA. Simvastatin inhibits stem cell proliferation in human leiomyoma via TGF-ß3 and Wnt/ß-Catenin pathways. J Cell Mol Med. 2022 03; 26(5):1684-1698. PMID: 35118811; PMCID: PMC8899165.
      Citations: 4     Fields:    Translation:Humans
    35. Ali M, Chen HY, Chiang YF, Badary OA, Hsia SM, Al-Hendy A. An evaluation of relugolix/estradiol/norethindrone acetate for the treatment of heavy menstrual bleeding associated with uterine fibroids in premenopausal women. Expert Opin Pharmacother. 2022 Mar; 23(4):421-429. PMID: 35068291; PMCID: PMC8866208.
      Citations: 1     Fields:    Translation:Humans
    36. Bateman NW, Tarney CM, Abulez TS, Hood BL, Conrads KA, Zhou M, Soltis AR, Teng PN, Jackson A, Tian C, Dalgard CL, Wilkerson MD, Kessler MD, Goecker Z, Loffredo J, Shriver CD, Hu H, Cote M, Parker GJ, Segars J, Al-Hendy A, Risinger JI, Phippen NT, Casablanca Y, Darcy KM, Maxwell GL, Conrads TP, O'Connor TD. Peptide ancestry informative markers in uterine neoplasms from women of European, African, and Asian ancestry. iScience. 2022 Jan 21; 25(1):103665. PMID: 35036865; PMCID: PMC8753123.
      Citations: 1     
    37. Madueke-Laveaux OS, Elsharoud A, Al-Hendy A. What We Know about the Long-Term Risks of Hysterectomy for Benign Indication-A Systematic Review. J Clin Med. 2021 Nov 16; 10(22). PMID: 34830617; PMCID: PMC8622061.
      Citations: 5     
    38. Cetin E, Siblini H, Al-Hendy A. What Is the Mechanism of Poor Endometrial Proliferation in Patients With Unexplained Infertility After Clomiphene Citrate Treatment? J Clin Endocrinol Metab. 2021 10 21; 106(11):e4776-e4777. PMID: 34192332; PMCID: PMC8530735.
      Citations:    Fields:    Translation:Humans
    39. Ali M, Raslan M, Ciebiera M, Zareba K, Al-Hendy A. Current approaches to overcome the side effects of GnRH analogs in the treatment of patients with uterine fibroids. Expert Opin Drug Saf. 2022 Apr; 21(4):477-486. PMID: 34612122; PMCID: PMC8940613.
      Citations: 3     Fields:    Translation:Humans
    40. Garcia N, Ulin M, Ali M, Al-Hendy A, Yang Q, Carvalho KC. Evaluation of Hedgehog Pathway Inhibitors as a Therapeutic Option for Uterine Leiomyosarcoma Using the Xenograft Model. Reprod Sci. 2022 03; 29(3):781-790. PMID: 34642915; PMCID: PMC8863774.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    41. Stewart EA, Archer DF, Owens CD, Barnhart KT, Bradley LD, Feinberg EC, Gillispie-Bell V, Imudia AN, Liu R, Kim JH, Al-Hendy A. Reduction of Heavy Menstrual Bleeding in Women Not Designated as Responders to Elagolix Plus Add Back Therapy for Uterine Fibroids. J Womens Health (Larchmt). 2022 05; 31(5):698-705. PMID: 34582715; PMCID: PMC9133968.
      Citations: 1     Fields:    Translation:Humans
    42. Afrin S, El Sabeh M, Islam MS, Miyashita-Ishiwata M, Malik M, Catherino WH, Akimzhanov AM, Boehning D, Yang Q, Al-Hendy A, Segars JH, Borahay MA. Simvastatin modulates estrogen signaling in uterine leiomyoma via regulating receptor palmitoylation, trafficking and degradation. Pharmacol Res. 2021 10; 172:105856. PMID: 34461224; PMCID: PMC8455458.
      Citations: 9     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    43. Chugh RM, Park HS, Esfandyari S, Elsharoud A, Ulin M, Al-Hendy A. Mesenchymal Stem Cell-Conditioned Media Regulate Steroidogenesis and Inhibit Androgen Secretion in a PCOS Cell Model via BMP-2. Int J Mol Sci. 2021 Aug 25; 22(17). PMID: 34502090; PMCID: PMC8431467.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    44. Watts NB, Binkley N, Owens CD, Al-Hendy A, Puscheck EE, Shebley M, Schlaff WD, Simon JA. Bone Mineral Density Changes Associated With Pregnancy, Lactation, and Medical Treatments in Premenopausal Women and Effects Later in Life. J Womens Health (Larchmt). 2021 10; 30(10):1416-1430. PMID: 34435897.
      Citations: 5     Fields:    Translation:Humans
    45. Garcia N, Ulin M, Al-Hendy A, Yang Q. The Role of Hedgehog Pathway in Uterine Leiomyosarcoma. J Cell Sci Ther. 2021; 12(Suppl 5). PMID: 34956733; PMCID: PMC8697743.
    46. Chugh RM, Park HS, El Andaloussi A, Elsharoud A, Esfandyari S, Ulin M, Bakir L, Aboalsoud A, Ali M, Ashour D, Igboeli P, Ismail N, McAllister J, Al-Hendy A. Mesenchymal stem cell therapy ameliorates metabolic dysfunction and restores fertility in a PCOS mouse model through interleukin-10. Stem Cell Res Ther. 2021 07 07; 12(1):388. PMID: 34233746; PMCID: PMC8261924.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    47. Al-Hendy A, Ku SY. Reproductive Tract Tissue/Organ Engineering and Regenerative Medicine for Reproduction. Reprod Sci. 2021 06; 28(6):1571-1572. PMID: 33905084.
      Citations:    Fields:    Translation:Humans
    48. Navarro A, Bariani MV, Yang Q, Al-Hendy A. Understanding the Impact of Uterine Fibroids on Human Endometrium Function. Front Cell Dev Biol. 2021; 9:633180. PMID: 34113609; PMCID: PMC8186666.
      Citations: 14     
    49. Ulin M, Cetin E, Hobeika E, Chugh RM, Park HS, Esfandyari S, Al-Hendy A. Human Mesenchymal Stem Cell Therapy and Other Novel Treatment Approaches for Premature Ovarian Insufficiency. Reprod Sci. 2021 06; 28(6):1688-1696. PMID: 33956339; PMCID: PMC8144118.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    50. Bateman NW, Tarney CM, Abulez T, Soltis AR, Zhou M, Conrads K, Litzi T, Oliver J, Hood B, Driggers P, Viollet C, Dalgard C, Wilkerson M, Catherino W, Hamilton CA, Darcy KM, Casablanca Y, Al-Hendy A, Segars J, Conrads TP, Larry Maxwell G. Proteogenomic landscape of uterine leiomyomas from hereditary leiomyomatosis and renal cell cancer patients. Sci Rep. 2021 04 30; 11(1):9371. PMID: 33931688; PMCID: PMC8087684.
      Citations: 5     Fields:    Translation:Humans
    51. Ciebiera M, Esfandyari S, Siblini H, Prince L, Elkafas H, Wojtyla C, Al-Hendy A, Ali M. Nutrition in Gynecological Diseases: Current Perspectives. Nutrients. 2021 Apr 02; 13(4). PMID: 33918317; PMCID: PMC8065992.
      Citations: 21     Fields:    Translation:Humans
    52. Park HS, Chugh RM, El Andaloussi A, Hobeika E, Esfandyari S, Elsharoud A, Ulin M, Garcia N, Bilal M, Al-Hendy A. Human BM-MSC secretome enhances human granulosa cell proliferation and steroidogenesis and restores ovarian function in primary ovarian insufficiency mouse model. Sci Rep. 2021 02 25; 11(1):4525. PMID: 33633319; PMCID: PMC7907146.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    53. Esfandyari S, Elkafas H, Chugh RM, Park HS, Navarro A, Al-Hendy A. Exosomes as Biomarkers for Female Reproductive Diseases Diagnosis and Therapy. Int J Mol Sci. 2021 Feb 22; 22(4). PMID: 33671587; PMCID: PMC7926632.
      Citations: 23     Fields:    Translation:HumansCells
    54. Al-Hendy A, Lukes AS, Poindexter AN, Venturella R, Villarroel C, Critchley HOD, Li Y, McKain L, Arjona Ferreira JC, Langenberg AGM, Wagman RB, Stewart EA. Treatment of Uterine Fibroid Symptoms with Relugolix Combination Therapy. N Engl J Med. 2021 02 18; 384(7):630-642. PMID: 33596357; PMCID: PMC8262231.
      Citations: 26     Fields:    Translation:HumansCTClinical Trials
    55. Park HS, Chugh RM, Elsharoud A, Ulin M, Esfandyari S, Aboalsoud A, Bakir L, Al-Hendy A. Safety of Intraovarian Injection of Human Mesenchymal Stem Cells in a Premature Ovarian Insufficiency Mouse Model. Cell Transplant. 2021 Jan-Dec; 30:963689720988502. PMID: 33593078; PMCID: PMC7894598.
      Citations: 9     Fields:    Translation:HumansAnimals
    56. Elkafas H, Badary O, Elmorsy E, Kamel R, Yang Q, Al-Hendy A. Endocrine-Disrupting Chemicals and Vitamin D Deficiency in the Pathogenesis of Uterine Fibroids. J Adv Pharm Res. 2021; 5(2):260-275. PMID: 34746367; PMCID: PMC8570385.
      Citations: 2     
    57. Garcia N, Al-Hendy A, Yang Q, Baracat EC, Carvalho KC. Targeting Hedgehog Pathway and DNA Methyltransferases in Uterine Leiomyosarcoma Cells. Cells. 2020 12 31; 10(1). PMID: 33396427; PMCID: PMC7824187.
      Citations: 9     Fields:    Translation:HumansCells
    58. Elsharoud A, Brakta S, Elhusseini H, Al-Hendy A. A presentation of ovarian fibrothecoma in a middle-aged female with recurrent massive ascites and postmenopausal bleeding: A case report. SAGE Open Med Case Rep. 2020; 8:2050313X20974222. PMID: 33425356; PMCID: PMC7758649.
    59. Bariani MV, Rangaswamy R, Siblini H, Yang Q, Al-Hendy A, Zota AR. The role of endocrine-disrupting chemicals in uterine fibroid pathogenesis. Curr Opin Endocrinol Diabetes Obes. 2020 12; 27(6):380-387. PMID: 33044243; PMCID: PMC8240765.
      Citations: 19     Fields:    Translation:HumansAnimalsPHPublic Health
    60. Leppert PC, Al-Hendy A, Baird DD, Bulun S, Catherino W, Dixon D, Ducharme M, Harmon QE, Jayes FL, Paul E, Perucho AM, Segars J, Stewart EA, Teixeira J, Tinelli A, Tschumperlin D, Zota AR, Simón C. Summary of the Proceedings of the Basic Science of Uterine Fibroids Meeting: New Developments February 28, 2020. F S Sci. 2021 02; 2(1):88-100. PMID: 34124698; PMCID: PMC8192074.
      Citations: 4     Fields:    Translation:Humans
    61. Ciebiera M, Ali M, Prince L, Zgliczynski S, Jakiel G, Al-Hendy A. The Significance of Measuring Vitamin D Serum Levels in Women with Uterine Fibroids. Reprod Sci. 2021 08; 28(8):2098-2109. PMID: 33108619; PMCID: PMC8262605.
      Citations: 7     Fields:    Translation:Humans
    62. Garcia N, Ulin M, Al-Hendy A, Yang Q. The Role of Hedgehog Pathway in Female Cancers. J Cancer Sci Clin Ther. 2020; 4(4):487-498. PMID: 33179013; PMCID: PMC7654982.
      Citations: 6     
    63. Esfandyari S, Chugh RM, Park HS, Hobeika E, Ulin M, Al-Hendy A. Mesenchymal Stem Cells as a Bio Organ for Treatment of Female Infertility. Cells. 2020 10 08; 9(10). PMID: 33050021; PMCID: PMC7599919.
      Citations: 28     Fields:    Translation:HumansCells
    64. Cetin E, Al-Hendy A, Ciebiera M. Non-hormonal mediators of uterine fibroid growth. Curr Opin Obstet Gynecol. 2020 10; 32(5):361-370. PMID: 32739973; PMCID: PMC8314923.
      Citations: 6     Fields:    Translation:HumansCells
    65. Ciebiera M, Ali M, Zgliczynska M, Skrzypczak M, Al-Hendy A. Vitamins and Uterine Fibroids: Current Data on Pathophysiology and Possible Clinical Relevance. Int J Mol Sci. 2020 Aug 01; 21(15). PMID: 32752274; PMCID: PMC7432695.
      Citations: 9     Fields:    Translation:Humans
    66. Al-Hendy A, Bradley L, Owens CD, Wang H, Barnhart KT, Feinberg E, Schlaff WD, Puscheck EE, Wang A, Gillispie V, Hurtado S, Muneyyirci-Delale O, Archer DF, Carr BR, Simon JA, Stewart EA. Predictors of response for elagolix with add-back therapy in women with heavy menstrual bleeding associated with uterine fibroids. Am J Obstet Gynecol. 2021 01; 224(1):72.e1-72.e50. PMID: 32702363; PMCID: PMC8800453.
      Citations: 8     Fields:    
    67. Igboeli P, El Andaloussi A, Sheikh U, Takala H, ElSharoud A, McHugh A, Gavrilova-Jordan L, Levy S, Al-Hendy A. Intraovarian injection of autologous human mesenchymal stem cells increases estrogen production and reduces menopausal symptoms in women with premature ovarian failure: two case reports and a review of the literature. J Med Case Rep. 2020 Jul 18; 14(1):108. PMID: 32680541; PMCID: PMC7368722.
      Citations: 22     Fields:    Translation:HumansCells
    68. Elkafas H, Ali M, Elmorsy E, Kamel R, Thompson WE, Badary O, Al-Hendy A, Yang Q. Vitamin D3 Ameliorates DNA Damage Caused by Developmental Exposure to Endocrine Disruptors in the Uterine Myometrial Stem Cells of Eker Rats. Cells. 2020 06 12; 9(6). PMID: 32545544; PMCID: PMC7349254.
      Citations: 17     Fields:    Translation:AnimalsCells
    69. Simon JA, Al-Hendy A, Archer DF, Barnhart KT, Bradley LD, Carr BR, Dayspring T, Feinberg EC, Gillispie V, Hurtado S, Kim J, Liu R, Owens CD, Muneyyirci-Delale O, Wang A, Watts NB, Schlaff WD. Elagolix Treatment for Up to 12 Months in Women With Heavy Menstrual Bleeding and Uterine Leiomyomas. Obstet Gynecol. 2020 06; 135(6):1313-1326. PMID: 32459423; PMCID: PMC7253187.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    70. Ali M, Esfandyari S, Al-Hendy A. Evolving role of microRNAs in uterine fibroid pathogenesis: filling the gap! Fertil Steril. 2020 06; 113(6):1167-1168. PMID: 32482253.
      Citations: 9     Fields:    Translation:HumansCells
    71. Ciebiera M, Ali M, Prince L, Jackson-Bey T, Atabiekov I, Zgliczynski S, Al-Hendy A. The Evolving Role of Natural Compounds in the Medical Treatment of Uterine Fibroids. J Clin Med. 2020 May 14; 9(5). PMID: 32423112; PMCID: PMC7290481.
      Citations: 8     
    72. Ali M, Shahin SM, Sabri NA, Al-Hendy A, Yang Q. Activation of ß-Catenin Signaling and its Crosstalk With Estrogen and Histone Deacetylases in Human Uterine Fibroids. J Clin Endocrinol Metab. 2020 04 01; 105(4). PMID: 31761932; PMCID: PMC7064306.
      Citations: 17     Fields:    Translation:HumansCells
    73. Small B, Millard CEF, Kisanga EP, Burman A, Anam A, Flannery C, Al-Hendy A, Whirledge S. The Selective Progesterone Receptor Modulator Ulipristal Acetate Inhibits the Activity of the Glucocorticoid Receptor. J Clin Endocrinol Metab. 2020 03 01; 105(3). PMID: 31665442; PMCID: PMC7112983.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    74. Ulin M, Ali M, Chaudhry ZT, Al-Hendy A, Yang Q. Uterine fibroids in menopause and perimenopause. Menopause. 2020 02; 27(2):238-242. PMID: 31834160; PMCID: PMC6994343.
      Citations: 22     Fields:    Translation:Humans
    75. Schlaff WD, Ackerman RT, Al-Hendy A, Archer DF, Barnhart KT, Bradley LD, Carr BR, Feinberg EC, Hurtado SM, Kim J, Liu R, Mabey RG, Owens CD, Poindexter A, Puscheck EE, Rodriguez-Ginorio H, Simon JA, Soliman AM, Stewart EA, Watts NB, Muneyyirci-Delale O. Elagolix for Heavy Menstrual Bleeding in Women with Uterine Fibroids. N Engl J Med. 2020 01 23; 382(4):328-340. PMID: 31971678.
      Citations: 49     Fields:    Translation:HumansCTClinical Trials
    76. Shalaby S, Khater M, Laknaur A, Arbab A, Al-Hendy A. Molecular Bio-Imaging Probe for Non-Invasive Differentiation Between Human Leiomyoma Versus Leiomyosarcoma. Reprod Sci. 2020 02; 27(2):644-654. PMID: 31925772; PMCID: PMC7539812.
      Citations: 3     Fields:    Translation:HumansCells
    77. El Andaloussi A, Al-Hendy A, Ismail N, Boyer TG, Halder SK. Introduction of Somatic Mutation in MED12 Induces Wnt4/ß-Catenin and Disrupts Autophagy in Human Uterine Myometrial Cell. Reprod Sci. 2020 03; 27(3):823-832. PMID: 32046450; PMCID: PMC7539814.
      Citations: 22     Fields:    Translation:HumansCells
    78. Ku SY, Al-Hendy A. Vision 20/20 for the Second Leap of Reproductive Sciences. Reprod Sci. 2020 01; 27(1):1-2. PMID: 32030671; PMCID: PMC7104448.
      Citations:    Fields:    Translation:Humans
    79. Takala H, Al-Hendy A, Yang Q. Neurotrimin: a novel neural cell adhesion molecule correlating with uterine fibroid phenotype. Fertil Steril. 2020 01; 113(1):83-84. PMID: 32033733.
      Citations:    Fields:    Translation:Humans
    80. Ali M, Prince L, Al-Hendy A. Vitamin D and uterine fibroids: preclinical evidence is in; time for an overdue clinical study! Fertil Steril. 2020 01; 113(1):89-90. PMID: 32033736.
      Citations: 7     Fields:    Translation:HumansAnimals
    81. Takala H, Yang Q, El Razek AMA, Ali M, Al-Hendy A. Alcohol Consumption and Risk of Uterine Fibroids. Curr Mol Med. 2020; 20(4):247-258. PMID: 31612831.
      Citations: 5     Fields:    Translation:Humans
    82. Park HS, Ashour D, Elsharoud A, Chugh RM, Ismail N, El Andaloussi A, Al-Hendy A. Towards Cell free Therapy of Premature Ovarian Insufficiency: Human Bone Marrow Mesenchymal Stem Cells Secretome Enhances Angiogenesis in Human Ovarian Microvascular Endothelial Cells. HSOA J Stem Cells Res Dev Ther. 2019; 5(2). PMID: 32494757; PMCID: PMC7269190.
      Citations: 11     
    83. Igboeli P, Walker W, McHugh A, Sultan A, Al-Hendy A. Burden of Uterine Fibroids: An African Perspective, A Call for Action and Opportunity for Intervention. Curr Opin Gynecol Obstet. 2019; 2(1):287-294. PMID: 32647835; PMCID: PMC7344264.
      Citations: 4     
    84. Omar M, Laknaur A, Al-Hendy A, Yang Q. Myometrial progesterone hyper-responsiveness associated with increased risk of human uterine fibroids. BMC Womens Health. 2019 07 09; 19(1):92. PMID: 31288815; PMCID: PMC6617862.
      Citations: 11     Fields:    Translation:Humans
    85. Cao T, Jiang Y, Wang Z, Zhang N, Al-Hendy A, Mamillapalli R, Kallen AN, Kodaman P, Taylor HS, Li D, Huang Y. H19 lncRNA identified as a master regulator of genes that drive uterine leiomyomas. Oncogene. 2019 07; 38(27):5356-5366. PMID: 31089260; PMCID: PMC6755985.
      Citations: 30     Fields:    Translation:HumansCells
    86. Ulin M, Al-Hendy A, Yang Q. Targeting the transforming growth factor-ß pathway: a novel mechanism of ulipristal acetate action against uterine fibroids. Fertil Steril. 2019 04; 111(4):683-684. PMID: 30929728.
      Citations: 1     Fields:    Translation:Humans
    87. Mohamed SA, Shalaby S, Brakta S, Elam L, Elsharoud A, Al-Hendy A. Umbilical Cord Blood Mesenchymal Stem Cells as an Infertility Treatment for Chemotherapy Induced Premature Ovarian Insufficiency. Biomedicines. 2019 Jan 18; 7(1). PMID: 30669278; PMCID: PMC6466426.
      Citations: 22     
    88. Ali M, Al-Hendy A, Yang Q. Vitamin D, a promising natural compound with anti-uterine fibroid characteristics. Fertil Steril. 2019 02; 111(2):268-269. PMID: 30598168.
      Citations: 6     Fields:    Translation:Humans
    89. Ali M, Shahin SM, Sabri NA, Al-Hendy A, Yang Q. 1,25 Dihydroxyvitamin D3 Enhances the Antifibroid Effects of Ulipristal Acetate in Human Uterine Fibroids. Reprod Sci. 2019 06; 26(6):812-828. PMID: 30514160; PMCID: PMC6728560.
      Citations: 15     Fields:    Translation:HumansCells
    90. Ali M, Jackson-Bey T, Al-Hendy A. Simvastatin and uterine fibroids: opportunity for a novel therapeutic option. Fertil Steril. 2018 12; 110(7):1272-1273. PMID: 30503124; PMCID: PMC7909745.
      Citations: 1     Fields:    Translation:HumansCells
    91. Brakta S, Mas A, Al-Hendy A. The ontogeny of myometrial stem cells in OCT4-GFP transgenic mouse model. Stem Cell Res Ther. 2018 11 29; 9(1):333. PMID: 30486855; PMCID: PMC6264618.
      Citations: 5     Fields:    Translation:AnimalsCells
    92. Ali M, Shahin SM, Sabri NA, Al-Hendy A, Yang Q. Hypovitaminosis D exacerbates the DNA damage load in human uterine fibroids, which is ameliorated by vitamin D3 treatment. Acta Pharmacol Sin. 2019 Jul; 40(7):957-970. PMID: 30478352; PMCID: PMC6786389.
      Citations: 23     Fields:    Translation:HumansCells
    93. Park MJ, Shen H, Kim NH, Gao F, Failor C, Knudtson JF, McLaughlin J, Halder SK, Heikkinen TA, Vahteristo P, Al-Hendy A, Schenken RS, Boyer TG. Mediator Kinase Disruption in MED12-Mutant Uterine Fibroids From Hispanic Women of South Texas. J Clin Endocrinol Metab. 2018 11 01; 103(11):4283-4292. PMID: 30099503; PMCID: PMC6194812.
      Citations: 11     Fields:    Translation:Humans
    94. Atabiekov I, Hobeika E, Sheikh U, El Andaloussi A, Al-Hendy A. The Role of Gene Therapy in Premature Ovarian Insufficiency Management. Biomedicines. 2018 Nov 01; 6(4). PMID: 30388808; PMCID: PMC6316312.
      Citations: 7     
    95. Carr BR, Stewart EA, Archer DF, Al-Hendy A, Bradley L, Watts NB, Diamond MP, Gao J, Owens CD, Chwalisz K, Duan WR, Soliman AM, Dufek MB, Simon JA. Elagolix Alone or With Add-Back Therapy in Women With Heavy Menstrual Bleeding and Uterine Leiomyomas: A Randomized Controlled Trial. Obstet Gynecol. 2018 11; 132(5):1252-1264. PMID: 30303923; PMCID: PMC7963450.
      Citations: 14     Fields:    Translation:Humans
    96. Prusinski Fernung LE, Yang Q, Sakamuro D, Kumari A, Mas A, Al-Hendy A. Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering DNA repair in myometrial stem cells. Biol Reprod. 2018 10 01; 99(4):735-748. PMID: 29688260; PMCID: PMC6203880.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    97. Marsh EE, Al-Hendy A, Kappus D, Galitsky A, Stewart EA, Kerolous M. Burden, Prevalence, and Treatment of Uterine Fibroids: A Survey of U.S. Women. J Womens Health (Larchmt). 2018 11; 27(11):1359-1367. PMID: 30230950; PMCID: PMC6247381.
      Citations: 44     Fields:    Translation:Humans
    98. Yang Q, Ali M, El Andaloussi A, Al-Hendy A. The emerging spectrum of early life exposure-related inflammation and epigenetic therapy. Cancer Stud Mol Med. 2018 Nov; 4(1):13-23. PMID: 30474062; PMCID: PMC6247815.
      Citations: 5     
    99. El Andaloussi A, Igboeli P, Amer A, Al-Hendy A. Intravenous Infusion of Nucleated Peripheral Blood Cells Restores Fertility in Mice with Chemotherapy-Induced Premature Ovarian Failure. Biomedicines. 2018 Sep 15; 6(3). PMID: 30223591; PMCID: PMC6163893.
      Citations: 2     
    100. Elhusseini H, Elkafas H, Abdelaziz M, Halder S, Atabiekov I, Eziba N, Ismail N, El Andaloussi A, Al-Hendy A. Diet-induced vitamin D deficiency triggers inflammation and DNA damage profile in murine myometrium. Int J Womens Health. 2018; 10:503-514. PMID: 30214319; PMCID: PMC6120572.
      Citations: 17     
    101. Ali M, Al-Hendy A. Uterine fibroid therapy: the pharmacokinetic considerations. Expert Opin Drug Metab Toxicol. 2018 Sep; 14(9):887-889. PMID: 30058386.
      Citations: 4     Fields:    Translation:Humans
    102. Prusinski Fernung LE, Jones K, Mas A, Kleven D, Waller JL, Al-Hendy A. Expanding upon the Human Myometrial Stem Cell Hypothesis and the Role of Race, Hormones, Age, and Parity in a Profibroid Environment. Am J Pathol. 2018 10; 188(10):2293-2306. PMID: 30075150; PMCID: PMC6168956.
      Citations: 6     Fields:    Translation:HumansCells
    103. Prusinski Fernung LE, Al-Hendy A, Yang Q. A Preliminary Study: Human Fibroid Stro-1+/CD44+ Stem Cells Isolated From Uterine Fibroids Demonstrate Decreased DNA Repair and Genomic Integrity Compared to Adjacent Myometrial Stro-1+/CD44+ Cells. Reprod Sci. 2019 05; 26(5):619-638. PMID: 29954254; PMCID: PMC6728578.
      Citations: 14     Fields:    Translation:HumansCells
    104. Habib S, El Andaloussi A, Elmasry K, Handoussa A, Azab M, Elsawey A, Al-Hendy A, Ismail N. PDL-1 Blockade Prevents T Cell Exhaustion, Inhibits Autophagy, and Promotes Clearance of Leishmania donovani. Infect Immun. 2018 06; 86(6). PMID: 29610255; PMCID: PMC5964517.
      Citations: 22     Fields:    Translation:AnimalsCells
    105. Yang Q, Al-Hendy A. The Emerging Role of p27 in Development of Diseases. Cancer Stud Mol Med. 2018 Nov; 4(1):e1-e3. PMID: 30474063; PMCID: PMC6247914.
      Citations: 5     
    106. Yang Q, Al-Hendy A. Non-coding RNAs: an important regulatory mechanism in pathogenesis of uterine fibroids. Fertil Steril. 2018 05; 109(5):802-803. PMID: 29778379; PMCID: PMC7990164.
      Citations: 3     Fields:    Translation:Humans
    107. Simon JA, Catherino W, Segars JH, Blakesley RE, Chan A, Sniukiene V, Al-Hendy A. Ulipristal Acetate for Treatment of Symptomatic Uterine Leiomyomas: A Randomized Controlled Trial. Obstet Gynecol. 2018 03; 131(3):431-439. PMID: 29420395; PMCID: PMC7968372.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    108. Park MJ, Shen H, Spaeth JM, Tolvanen JH, Failor C, Knudtson JF, McLaughlin J, Halder SK, Yang Q, Bulun SE, Al-Hendy A, Schenken RS, Aaltonen LA, Boyer TG. Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19. J Biol Chem. 2018 03 30; 293(13):4870-4882. PMID: 29440396; PMCID: PMC5880139.
      Citations: 24     Fields:    Translation:HumansCells
    109. Ali M, Chaudhry ZT, Al-Hendy A. Successes and failures of uterine leiomyoma drug discovery. Expert Opin Drug Discov. 2018 02; 13(2):169-177. PMID: 29254389.
      Citations: 20     Fields:    Translation:HumansAnimals
    110. Segars JH, Al-Hendy A. Uterine Leiomyoma: New Perspectives on an Old Disease. Semin Reprod Med. 2017 11; 35(6):471-472. PMID: 29100233.
      Citations: 5     Fields:    Translation:Humans
    111. Al-Hendy A, Myers ER, Stewart E. Uterine Fibroids: Burden and Unmet Medical Need. Semin Reprod Med. 2017 11; 35(6):473-480. PMID: 29100234; PMCID: PMC6193285.
      Citations: 61     Fields:    Translation:Humans
    112. El Andaloussi A, Chaudhry Z, Al-Hendy A, Ismail N. Uterine Fibroids: Bridging Genomic Defects and Chronic Inflammation. Semin Reprod Med. 2017 11; 35(6):494-498. PMID: 29100237.
      Citations: 10     Fields:    Translation:Humans
    113. Elkafas H, Qiwei Y, Al-Hendy A. Origin of Uterine Fibroids: Conversion of Myometrial Stem Cells to Tumor-Initiating Cells. Semin Reprod Med. 2017 11; 35(6):481-486. PMID: 29100235.
      Citations: 14     Fields:    Translation:HumansCells
    114. Abdelaziz M, Eziba N, Sharma S, Kleven D, Al-Hendy A. Cervical superficial myofibroblastoma: Case report and review of the literature. SAGE Open Med Case Rep. 2017; 5:2050313X17726936. PMID: 28904795; PMCID: PMC5588789.
      Citations: 3     
    115. Ali M, Al-Hendy A. Selective progesterone receptor modulators for fertility preservation in women with symptomatic uterine fibroids. Biol Reprod. 2017 Sep 01; 97(3):337-352. PMID: 29025038; PMCID: PMC5803778.
      Citations: 21     Fields:    Translation:Humans
    116. Andaloussi AE, Habib S, Soylemes G, Laknaur A, Elhusseini H, Al-Hendy A, Ismail N. Defective expression of ATG4D abrogates autophagy and promotes growth in human uterine fibroids. Cell Death Discov. 2017; 3:17041. PMID: 28815060; PMCID: PMC5554887.
      Citations: 13     
    117. Mohamed SA, El Andaloussi A, Al-Hendy A, Menon R, Behnia F, Schulkin J, Power ML. Vitamin D and corticotropin-releasing hormone in term and preterm birth: potential contributions to preterm labor and birth outcome. J Matern Fetal Neonatal Med. 2018 Nov; 31(21):2911-2917. PMID: 28780891.
      Citations: 4     Fields:    Translation:HumansCells
    118. Fletcher NM, Abusamaan MS, Memaj I, Saed MG, Al-Hendy A, Diamond MP, Saed GM. Oxidative stress: a key regulator of leiomyoma cell survival. Fertil Steril. 2017 06; 107(6):1387-1394.e1. PMID: 28483502.
      Citations: 11     Fields:    Translation:HumansCells
    119. Mohamed SA, Shalaby SM, Abdelaziz M, Brakta S, Hill WD, Ismail N, Al-Hendy A. Human Mesenchymal Stem Cells Partially Reverse Infertility in Chemotherapy-Induced Ovarian Failure. Reprod Sci. 2018 01; 25(1):51-63. PMID: 28460567; PMCID: PMC6344979.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    120. Al-Hendy A, Laknaur A, Diamond MP, Ismail N, Boyer TG, Halder SK. Silencing Med12 Gene Reduces Proliferation of Human Leiomyoma Cells Mediated via Wnt/ß-Catenin Signaling Pathway. Endocrinology. 2017 03 01; 158(3):592-603. PMID: 27967206; PMCID: PMC5460776.
      Citations: 40     Fields:    Translation:HumansCells
    121. Mas A, Prusinski L, Yang Q, Diaz-Gimeno P, Stone L, Diamond MP, Al-Hendy A, Simón C. Role of Stro1+/CD44+ stem cells in myometrial physiology and uterine remodeling during pregnancy. Biol Reprod. 2017 01 01; 96(1):70-80. PMID: 28395335; PMCID: PMC5803774.
      Citations: 8     Fields:    Translation:AnimalsCells
    122. Yang Q, Al-Hendy A. Developmental Environmental Exposure Alters the Epigenetic Features of Myometrial Stem Cells. Gynecol Obstet Res. 2016 Dec; 3(2):e1-e4. PMID: 28626795; PMCID: PMC5473610.
      Citations: 6     
    123. Borahay MA, Asoglu MR, Mas A, Adam S, Kilic GS, Al-Hendy A. Estrogen Receptors and Signaling in Fibroids: Role in Pathobiology and Therapeutic Implications. Reprod Sci. 2017 09; 24(9):1235-1244. PMID: 27872195; PMCID: PMC6344829.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    124. Mas A, Stone L, O'Connor PM, Yang Q, Kleven D, Simon C, Walker CL, Al-Hendy A. Developmental Exposure to Endocrine Disruptors Expands Murine Myometrial Stem Cell Compartment as a Prerequisite to Leiomyoma Tumorigenesis. Stem Cells. 2017 03; 35(3):666-678. PMID: 27739139.
      Citations: 26     Fields:    Translation:HumansAnimalsPHPublic Health
    125. Chuang TY, Min J, Wu HL, McCrary C, Layman LC, Diamond MP, Azziz R, Al-Hendy A, Chen YH. Berberine Inhibits Uterine Leiomyoma Cell Proliferation via Downregulation of Cyclooxygenase 2 and Pituitary Tumor-Transforming Gene 1. Reprod Sci. 2017 07; 24(7):1005-1013. PMID: 27799459.
      Citations: 4     Fields:    Translation:AnimalsCells
    126. Halder S, Al-Hendy A. Hypovitaminosis D and high serum transforming growth factor beta-3: important biomarkers for uterine fibroids risk. Fertil Steril. 2016 12; 106(7):1648-1649. PMID: 27793369; PMCID: PMC7344336.
      Citations: 12     Fields:    Translation:Humans
    127. Atta HM, Al-Hendy AA, Abdel Raheim SR, Abdel-Ghany H, Nasif KA, Abdellah AM, Zenhom NM, Kamel HS. Modified Adenovirus Reduces De Novo Peritoneal Adhesions in Rats and Limits Off-Target Transfection. Role of EZH2 in Adhesion Formation. J Invest Surg. 2017 Apr; 30(2):78-87. PMID: 27690696.
      Citations:    Fields:    Translation:HumansAnimalsCells
    128. Latif E, Adam S, Rungruang B, Al-Hendy A, Diamond MP, Rotem E, Cannell J, Browne PC. Use of uterine artery embolization to prevent peripartum hemorrhage of placental abruption with fetal demise & severe DIC. J Neonatal Perinatal Med. 2016 Sep 16; 9(3):325-31. PMID: 27589544.
      Citations: 1     Fields:    Translation:Humans
    129. Mohamed SA, Al-Hendy A, Schulkin J, Power ML. Opinions and Practice of US-Based Obstetrician-Gynecologists regarding Vitamin D Screening and Supplementation of Pregnant Women. J Pregnancy. 2016; 2016:1454707. PMID: 27648304; PMCID: PMC5014971.
      Citations: 3     Fields:    Translation:Humans
    130. Katz TA, Yang Q, Walker CL, Al-Hendy A, Treviño LS. Endocrine-disrupting chemicals and uterine fibroids. Fertil Steril. 2016 09 15; 106(4):967-77. PMID: 27553264; PMCID: PMC5051569.
      Citations: 23     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    131. Othman ER, Elgamal DA, Refaiy AM, Abdelaal II, Abdel-Mola AF, Al-Hendy A. Identification and potential role of telocytes in human uterine leiomyoma. Contracept Reprod Med. 2016; 1:12. PMID: 29201401; PMCID: PMC5693520.
      Citations: 6     
    132. Prusinski L, Al-Hendy A, Yang Q. Developmental exposure to endocrine disrupting chemicals alters the epigenome: Identification of reprogrammed targets. Gynecol Obstet Res. 2016 Jul; 3(1):1-6. PMID: 27478869; PMCID: PMC4966680.
      Citations: 19     
    133. Yang Q, Diamond MP, Al-Hendy A. Converting of Myometrial Stem Cells to Tumor-Initiating Cells: Mechanism of Uterine Fibroid Development. Cell Stem Cells Regen Med. 2016 Apr; 2(1). PMID: 28042616; PMCID: PMC5199021.
      Citations: 9     
    134. Yang Q, Laknaur A, Elam L, Ismail N, Gavrilova-Jordan L, Lue J, Diamond MP, Al-Hendy A. Identification of Polycomb Group Protein EZH2-Mediated DNA Mismatch Repair Gene MSH2 in Human Uterine Fibroids. Reprod Sci. 2016 10; 23(10):1314-25. PMID: 27036951; PMCID: PMC5933176.
      Citations: 11     Fields:    Translation:HumansCells
    135. Shalaby SM, Khater MK, Perucho AM, Mohamed SA, Helwa I, Laknaur A, Lebedyeva I, Liu Y, Diamond MP, Al-Hendy AA. Magnetic nanoparticles as a new approach to improve the efficacy of gene therapy against differentiated human uterine fibroid cells and tumor-initiating stem cells. Fertil Steril. 2016 06; 105(6):1638-1648.e8. PMID: 27020169; PMCID: PMC4971775.
      Citations: 13     Fields:    Translation:HumansCells
    136. Yang Q, Diamond MP, Al-Hendy A. Early Life Adverse Environmental Exposures Increase the Risk of Uterine Fibroid Development: Role of Epigenetic Regulation. Front Pharmacol. 2016; 7:40. PMID: 26973527; PMCID: PMC4772696.
      Citations: 26     
    137. Othman ER, Hussein M, Abdelaal II, Sayed AA, Fetih AN, Al-Hendy A, Hornung D. Soluble tumor necrosis factor-alpha receptors in the serum of endometriosis patients. Eur J Obstet Gynecol Reprod Biol. 2016 May; 200:1-5. PMID: 26963895.
      Citations: 2     Fields:    Translation:Humans
    138. Yang Q, Nair S, Laknaur A, Ismail N, Diamond MP, Al-Hendy A. The Polycomb Group Protein EZH2 Impairs DNA Damage Repair Gene Expression in Human Uterine Fibroids. Biol Reprod. 2016 Mar; 94(3):69. PMID: 26888970; PMCID: PMC4829092.
      Citations: 19     Fields:    Translation:HumansCells
    139. Abdelaziz M, Sherif L, ElKhiary M, Nair S, Shalaby S, Mohamed S, Eziba N, El-Lakany M, Curiel D, Ismail N, Diamond MP, Al-Hendy A. Targeted Adenoviral Vector Demonstrates Enhanced Efficacy for In Vivo Gene Therapy of Uterine Leiomyoma. Reprod Sci. 2016 Apr; 23(4):464-74. PMID: 26884457; PMCID: PMC5933189.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    140. Othman ER, Curiel DT, Hussein M, Abdelaal II, Fetih AN, Al-Hendy A. Enhancing Adenoviral-Mediated Gene Transfer and Expression to Endometrial Cells. Reprod Sci. 2016 08; 23(8):1109-15. PMID: 26865542.
      Citations:    Fields:    Translation:HumansCells
    141. Mohamed SA, Al-Hendy A, Ghamande S, Chaffin J, Browne P. Atypical Presentations of Molar Pregnancy: Diagnostic Roles of Imaging, ß-Human Chorionic Gonadotropin Measurement, and p57 Immunostaining. J Ultrasound Med. 2016 Mar; 35(3):643-9. PMID: 26860483.
      Citations:    Fields:    Translation:Humans
    142. Yang Q, Diamond MP, Al-Hendy A. The emerging role of extracellular vesicle-derived miRNAs: implication in cancer progression and stem cell related diseases. J Clin Epigenet. 2016; 2(1). PMID: 27099870; PMCID: PMC4834835.
      Citations: 33     
    143. Al-Hendy A, Diamond MP, Boyer TG, Halder SK. Vitamin D3 Inhibits Wnt/ß-Catenin and mTOR Signaling Pathways in Human Uterine Fibroid Cells. J Clin Endocrinol Metab. 2016 04; 101(4):1542-51. PMID: 26820714; PMCID: PMC4880168.
      Citations: 34     Fields:    Translation:HumansCells
    144. Parker W, Berek JS, Pritts E, Olive D, Kaunitz AM, Chalas E, Clarke-Pearson D, Goff B, Bristow R, Taylor HS, Farias-Eisner R, Fader AN, Maxwell GL, Goodwin SC, Love S, Gibbons WE, Foshag LJ, Leppert PC, Norsigian J, Nager CW, Johnson T, Guzick DS, As-Sanie S, Paulson RJ, Farquhar C, Bradley L, Scheib SA, Bilchik AJ, Rice LW, Dionne C, Jacoby A, Ascher-Walsh C, Kilpatrick SJ, Adamson GD, Siedhoff M, Israel R, Paraiso MF, Frumovitz MM, Lurain JR, Al-Hendy A, Benrubi GI, Raman SS, Kho RM, Anderson TL, Reynolds RK, DeLancey J. An Open Letter to the Food and Drug Administration Regarding the Use of Morcellation Procedures in Women Having Surgery for Presumed Uterine Myomas. J Minim Invasive Gynecol. 2016 Mar-Apr; 23(3):303-8. PMID: 26773577.
      Citations: 3     Fields:    
    145. Laknaur A, Foster TL, Bobb LE, Ramesh A, Ladson GM, Hood DB, Al-Hendy A, Thota C. Altered expression of histone deacetylases, inflammatory cytokines and contractile-associated factors in uterine myometrium of Long Evans rats gestationally exposed to benzo[a]pyrene. J Appl Toxicol. 2016 Jun; 36(6):827-35. PMID: 26358852; PMCID: PMC5404737.
      Citations: 4     Fields:    Translation:Animals
    146. Brakta S, Diamond JS, Al-Hendy A, Diamond MP, Halder SK. Role of vitamin D in uterine fibroid biology. Fertil Steril. 2015 Sep; 104(3):698-706. PMID: 26079694; PMCID: PMC4561014.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    147. Mas A, Nair S, Laknaur A, Diamond MP, Al-Hendy A, Simón C. Stro-1/CD44 as putative human myometrial and fibroid stem cell markers. Fertil Steril. 2015 Jul; 104(1):225-34.e3. PMID: 25989979; PMCID: PMC4490118.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    148. Yang Q, Mas A, Diamond MP, Al-Hendy A. The Mechanism and Function of Epigenetics in Uterine Leiomyoma Development. Reprod Sci. 2016 Feb; 23(2):163-75. PMID: 25922306; PMCID: PMC5933172.
      Citations: 55     Fields:    Translation:HumansCells
    149. Borahay MA, Al-Hendy A, Kilic GS, Boehning D. Signaling Pathways in Leiomyoma: Understanding Pathobiology and Implications for Therapy. Mol Med. 2015 Apr 13; 21:242-56. PMID: 25879625; PMCID: PMC4503645.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    150. Borahay MA, Vincent K, Motamedi M, Sbrana E, Kilic GS, Al-Hendy A, Boehning D. Novel effects of simvastatin on uterine fibroid tumors: in vitro and patient-derived xenograft mouse model study. Am J Obstet Gynecol. 2015 Aug; 213(2):196.e1-8. PMID: 25840272; PMCID: PMC4519389.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    151. Nothnick WB, Al-Hendy A, Lue JR. Circulating Micro-RNAs as Diagnostic Biomarkers for Endometriosis: Privation and Promise. J Minim Invasive Gynecol. 2015 Jul-Aug; 22(5):719-26. PMID: 25757811; PMCID: PMC4489990.
      Citations: 8     Fields:    Translation:Humans
    152. Wu HL, Chuang TY, Al-Hendy A, Diamond MP, Azziz R, Chen YH. Berberine inhibits the proliferation of human uterine leiomyoma cells. Fertil Steril. 2015 Apr; 103(4):1098-106. PMID: 25682924.
      Citations: 10     Fields:    Translation:HumansCells
    153. Al-Hendy A, Diamond MP, El-Sohemy A, Halder SK. 1,25-dihydroxyvitamin D3 regulates expression of sex steroid receptors in human uterine fibroid cells. J Clin Endocrinol Metab. 2015 Apr; 100(4):E572-82. PMID: 25625804; PMCID: PMC4399292.
      Citations: 35     Fields:    Translation:HumansCells
    154. Atta H, El-Rehany M, Hammam O, Abdel-Ghany H, Ramzy M, Roderfeld M, Roeb E, Al-Hendy A, Raheim SA, Allam H, Marey H. Mutant MMP-9 and HGF gene transfer enhance resolution of CCl4-induced liver fibrosis in rats: role of ASH1 and EZH2 methyltransferases repression. PLoS One. 2014; 9(11):e112384. PMID: 25380300; PMCID: PMC4224431.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    155. Borahay MA, Kilic GS, Yallampalli C, Snyder RR, Hankins GD, Al-Hendy A, Boehning D. Simvastatin potently induces calcium-dependent apoptosis of human leiomyoma cells. J Biol Chem. 2014 Dec 19; 289(51):35075-86. PMID: 25359773; PMCID: PMC4271198.
      Citations: 36     Fields:    Translation:HumansCells
    156. Halder SK, Laknaur A, Miller J, Layman LC, Diamond M, Al-Hendy A. Novel MED12 gene somatic mutations in women from the Southern United States with symptomatic uterine fibroids. Mol Genet Genomics. 2015 Apr; 290(2):505-11. PMID: 25325994; PMCID: PMC4682355.
      Citations: 37     Fields:    Translation:Humans
    157. Moghazy D, Sharan C, Nair M, Rackauskas C, Burnette R, Diamond M, Al-Hendy O, Al-Hendy A. Sertoli-Leydig cell tumor with unique nail findings in a post-menopausal woman: a case report and literature review. J Ovarian Res. 2014 Aug 28; 7:83. PMID: 25296983; PMCID: PMC4244065.
      Citations: 3     Fields:    Translation:Humans
    158. Stilley JA, Christensen DE, Dahlem KB, Guan R, Santillan DA, England SK, Al-Hendy A, Kirby PA, Segaloff DL. FSH receptor (FSHR) expression in human extragonadal reproductive tissues and the developing placenta, and the impact of its deletion on pregnancy in mice. Biol Reprod. 2014 Sep; 91(3):74. PMID: 25100706; PMCID: PMC4435062.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    159. Al-Hendy A, Badr M. Can vitamin D reduce the risk of uterine fibroids? Womens Health (Lond). 2014 Jul; 10(4):353-8. PMID: 25259897; PMCID: PMC4209245.
      Citations: 11     Fields:    Translation:HumansAnimals
    160. Zhang D, Rajaratnam V, Al-Hendy O, Halder S, Al-Hendy A. Green tea extract inhibition of human leiomyoma cell proliferation is mediated via catechol-O-methyltransferase. Gynecol Obstet Invest. 2014; 78(2):109-18. PMID: 24942317.
      Citations: 6     Fields:    Translation:HumansCells
    161. Halder SK, Sharan C, Al-Hendy O, Al-Hendy A. Paricalcitol, a vitamin d receptor activator, inhibits tumor formation in a murine model of uterine fibroids. Reprod Sci. 2014 Sep; 21(9):1108-19. PMID: 24925855; PMCID: PMC4212343.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    162. Moghazy D, Al-Hendy O, Al-Hendy A. Krukenberg tumor presenting as back pain and a positive urine pregnancy test: a case report and literature review. J Ovarian Res. 2014 Apr 07; 7:36. PMID: 24708577; PMCID: PMC4234994.
      Citations: 4     Fields:    Translation:Humans
    163. Fletcher NM, Saed MG, Abuanzeh S, Abu-Soud HM, Al-Hendy A, Diamond MP, Saed GM. Nicotinamide adenine dinucleotide phosphate oxidase is differentially regulated in normal myometrium versus leiomyoma. Reprod Sci. 2014 Sep; 21(9):1145-52. PMID: 24520084; PMCID: PMC5933080.
      Citations: 10     Fields:    Translation:HumansCells
    164. Mohamed SA, Thota C, Browne PC, Diamond MP, Al-Hendy A. Why is Preterm Birth Stubbornly Higher in African-Americans? Obstet Gynecol Int J. 2014; 1(3). PMID: 25905109; PMCID: PMC4402979.
      Citations: 6     
    165. Halder SK, Osteen KG, Al-Hendy A. 1,25-dihydroxyvitamin d3 reduces extracellular matrix-associated protein expression in human uterine fibroid cells. Biol Reprod. 2013 Dec; 89(6):150. PMID: 24174578; PMCID: PMC4076359.
      Citations: 48     Fields:    Translation:HumansCells
    166. Thota C, Laknaur A, Farmer T, Ladson G, Al-Hendy A, Ismail N. Vitamin D regulates contractile profile in human uterine myometrial cells via NF-?B pathway. Am J Obstet Gynecol. 2014 Apr; 210(4):347.e1-347.e10. PMID: 24262718; PMCID: PMC3972355.
      Citations: 21     Fields:    Translation:HumansCells
    167. Nair S, Nguyen H, Salama S, Al-Hendy A. Obesity and the Endometrium: Adipocyte-Secreted Proinflammatory TNF a Cytokine Enhances the Proliferation of Human Endometrial Glandular Cells. Obstet Gynecol Int. 2013; 2013:368543. PMID: 24288542; PMCID: PMC3832969.
      Citations: 9     
    168. Catherino WH, Eltoukhi HM, Al-Hendy A. Racial and ethnic differences in the pathogenesis and clinical manifestations of uterine leiomyoma. Semin Reprod Med. 2013 Sep; 31(5):370-9. PMID: 23934698; PMCID: PMC4170830.
      Citations: 44     Fields:    Translation:HumansAnimals
    169. Roshdy E, Rajaratnam V, Maitra S, Sabry M, Allah AS, Al-Hendy A. Treatment of symptomatic uterine fibroids with green tea extract: a pilot randomized controlled clinical study. Int J Womens Health. 2013; 5:477-86. PMID: 23950663; PMCID: PMC3742155.
      Citations: 30     
    170. Nair S, Saed GM, Atta HM, Rajaratnam V, Diamond MP, Curiel DT, Al-Hendy A. Towards gene therapy of postoperative adhesions: fiber and transcriptional modifications enhance adenovirus targeting towards human adhesion cells. Gynecol Obstet Invest. 2013; 76(2):119-24. PMID: 23920223; PMCID: PMC4172483.
      Citations: 7     Fields:    Translation:HumansCells
    171. Nair S, Curiel DT, Rajaratnam V, Thota C, Al-Hendy A. Targeting adenoviral vectors for enhanced gene therapy of uterine leiomyomas. Hum Reprod. 2013 Sep; 28(9):2398-406. PMID: 23820419; PMCID: PMC3748860.
      Citations: 10     Fields:    Translation:HumansCells
    172. Fletcher NM, Saed MG, Abu-Soud HM, Al-Hendy A, Diamond MP, Saed GM. Uterine fibroids are characterized by an impaired antioxidant cellular system: potential role of hypoxia in the pathophysiology of uterine fibroids. J Assist Reprod Genet. 2013 Jul; 30(7):969-74. PMID: 23812845; PMCID: PMC3725220.
      Citations: 14     Fields:    Translation:HumansCells
    173. Halder SK, Osteen KG, Al-Hendy A. Vitamin D3 inhibits expression and activities of matrix metalloproteinase-2 and -9 in human uterine fibroid cells. Hum Reprod. 2013 Sep; 28(9):2407-16. PMID: 23814095; PMCID: PMC3748859.
      Citations: 47     Fields:    Translation:HumansCells
    174. Thota C, Menon R, Fortunato SJ, Brou L, Lee JE, Al-Hendy A. 1,25-Dihydroxyvitamin D deficiency is associated with preterm birth in African American and Caucasian women. Reprod Sci. 2014 Feb; 21(2):244-50. PMID: 23793474; PMCID: PMC3879992.
      Citations: 17     Fields:    Translation:Humans
    175. Ravella K, Al-Hendy A, Sharan C, Hale AB, Channon KM, Srinivasan S, Gangula PR. Chronic estrogen deficiency causes gastroparesis by altering neuronal nitric oxide synthase function. Dig Dis Sci. 2013 Jun; 58(6):1507-15. PMID: 23504347; PMCID: PMC3691310.
      Citations: 16     Fields:    Translation:AnimalsCells
    176. Sabry M, Halder SK, Allah AS, Roshdy E, Rajaratnam V, Al-Hendy A. Serum vitamin D3 level inversely correlates with uterine fibroid volume in different ethnic groups: a cross-sectional observational study. Int J Womens Health. 2013; 5:93-100. PMID: 23467803; PMCID: PMC3589082.
      Citations: 56     
    177. Gangula PR, Dong YL, Al-Hendy A, Richard-Davis G, Montgomery-Rice V, Haddad G, Millis R, Nicholas SB, Moseberry D. Protective cardiovascular and renal actions of vitamin D and estrogen. Front Biosci (Schol Ed). 2013 01 01; 5(1):134-48. PMID: 23277041; PMCID: PMC3673780.
      Citations: 7     Fields:    Translation:HumansAnimals
    178. Thota C, Farmer T, Garfield RE, Menon R, Al-Hendy A. Vitamin D elicits anti-inflammatory response, inhibits contractile-associated proteins, and modulates Toll-like receptors in human myometrial cells. Reprod Sci. 2013 Apr; 20(4):463-75. PMID: 23012315; PMCID: PMC3823395.
      Citations: 28     Fields:    Translation:HumansCells
    179. Peggs KJ, Nguyen H, Enayat D, Keller NR, Al-Hendy A, Raj SR. Gynecologic disorders and menstrual cycle lightheadedness in postural tachycardia syndrome. Int J Gynaecol Obstet. 2012 Sep; 118(3):242-6. PMID: 22721633; PMCID: PMC3413773.
      Citations: 12     Fields:    Translation:Humans
    180. Sabry M, Ait Allah AS, Roshdy E, Al-Hendy A. Laparoscopic management of a large torted ovarian cyst in an adolescent virgin: a case report. Int J Womens Health. 2012; 4:223-5. PMID: 22675267; PMCID: PMC3367404.
    181. Halder SK, Sharan C, Al-Hendy A. 1,25-dihydroxyvitamin D3 treatment shrinks uterine leiomyoma tumors in the Eker rat model. Biol Reprod. 2012 Apr; 86(4):116. PMID: 22302692; PMCID: PMC3338660.
      Citations: 55     Fields:    Translation:Animals
    182. Vargis E, Brown N, Williams K, Al-Hendy A, Paria BC, Reese J, Mahadevan-Jansen A. Detecting biochemical changes in the rodent cervix during pregnancy using Raman spectroscopy. Ann Biomed Eng. 2012 Aug; 40(8):1814-24. PMID: 22411265; PMCID: PMC3739433.
      Citations: 13     Fields:    Translation:Animals
    183. Ghadami M, El-Demerdash E, Zhang D, Salama SA, Binhazim AA, Archibong AE, Chen X, Ballard BR, Sairam MR, Al-Hendy A. Bone marrow transplantation restores follicular maturation and steroid hormones production in a mouse model for primary ovarian failure. PLoS One. 2012; 7(3):e32462. PMID: 22412875; PMCID: PMC3296713.
      Citations: 17     Fields:    Translation:Animals
    184. Sabry M, Al-Hendy A. Medical treatment of uterine leiomyoma. Reprod Sci. 2012 Apr; 19(4):339-53. PMID: 22378865; PMCID: PMC3343067.
      Citations: 53     Fields:    Translation:Humans
    185. Sabry M, Al-Hendy A. Innovative oral treatments of uterine leiomyoma. Obstet Gynecol Int. 2012; 2012:943635. PMID: 22518167; PMCID: PMC3306913.
      Citations: 24     
    186. Nair S, Al-Hendy A, Tamboli RA, Marks-Shulman PA, Abumrad NN. Increased COMT expression in PCOS biology. Mol Cell Endocrinol. 2012 May 15; 355(1):188-9. PMID: 22342814.
      Citations:    Fields:    Translation:Humans
    187. Thota C, Menon R, Wentz MJ, Fortunato SJ, Bartlett J, Drobek CO, Nair S, Al-Hendy A. A single-nucleotide polymorphism in the fetal catechol-O-methyltransferase gene is associated with spontaneous preterm birth in African Americans. Reprod Sci. 2012 Feb; 19(2):135-42. PMID: 22158829; PMCID: PMC3343133.
      Citations: 5     Fields:    Translation:Humans
    188. Nair S, Al-Hendy A. Adipocytes enhance the proliferation of human leiomyoma cells via TNF-a proinflammatory cytokine. Reprod Sci. 2011 Dec; 18(12):1186-92. PMID: 22096007; PMCID: PMC3343097.
      Citations: 22     Fields:    Translation:HumansCells
    189. Hassan MH, Fouad H, Bahashwan S, Al-Hendy A. Towards non-surgical therapy for uterine fibroids: catechol-O-methyl transferase inhibitor shrinks uterine fibroid lesions in the Eker rat model. Hum Reprod. 2011 Nov; 26(11):3008-18. PMID: 21896544; PMCID: PMC3196875.
      Citations: 8     Fields:    Translation:AnimalsCells
    190. Goodwin JS, Al-Hendy A, Halder SK. 1,25-Dihydroxyvitamin D3 reduces TGF-beta3-induced fibrosis-related gene expression in human uterine leiomyoma cells. J Clin Endocrinol Metab. 2011 Apr; 96(4):E754-62. PMID: 21289245; PMCID: PMC3070259.
      Citations: 70     Fields:    Translation:HumansCells
    191. Sharan C, Halder SK, Thota C, Jaleel T, Nair S, Al-Hendy A. Vitamin D inhibits proliferation of human uterine leiomyoma cells via catechol-O-methyltransferase. Fertil Steril. 2011 Jan; 95(1):247-53. PMID: 20736132; PMCID: PMC2992588.
      Citations: 66     Fields:    Translation:HumansCells
    192. Ghadami M, El-Demerdash E, Salama SA, Binhazim AA, Archibong AE, Chen X, Ballard BR, Sairam MR, Al-Hendy A. Toward gene therapy of premature ovarian failure: intraovarian injection of adenovirus expressing human FSH receptor restores folliculogenesis in FSHR(-/-) FORKO mice. Mol Hum Reprod. 2010 Apr; 16(4):241-50. PMID: 20086006; PMCID: PMC2834408.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    193. Zhang D, Al-Hendy M, Richard-Davis G, Montgomery-Rice V, Sharan C, Rajaratnam V, Khurana A, Al-Hendy A. Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice. Am J Obstet Gynecol. 2010 Mar; 202(3):289.e1-9. PMID: 20074693; PMCID: PMC2834812.
      Citations: 35     Fields:    Translation:AnimalsCells
    194. Zhang D, Al-Hendy M, Richard-Davis G, Montgomery-Rice V, Rajaratnam V, Al-Hendy A. Antiproliferative and proapoptotic effects of epigallocatechin gallate on human leiomyoma cells. Fertil Steril. 2010 Oct; 94(5):1887-93. PMID: 19819432; PMCID: PMC2891261.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    195. Harirah H, Thota C, Wentz MJ, Zaman W, Al-Hendy A. Elevated expression of catechol-O-methyltransferase is associated with labor and increased prostaglandin E(2) production by human fetal membranes. Am J Obstet Gynecol. 2009 Nov; 201(5):496.e1-7. PMID: 19664748; PMCID: PMC2784115.
      Citations: 5     Fields:    Translation:Humans
    196. Atta HM, Al-Hendy A, El-Rehany MA, Dewerchin M, Abdel Raheim SR, Abdel Ghany H, Fouad R. Adenovirus-mediated overexpression of human tissue plasminogen activator prevents peritoneal adhesion formation/reformation in rats. Surgery. 2009 Jul; 146(1):12-7. PMID: 19541005.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    197. Atta HM, Al-Hendy A, Salama SA, Shaker OG, Hammam OA. Low-dose simultaneous delivery of adenovirus encoding hepatocyte growth factor and vascular endothelial growth factor in dogs enhances liver proliferation without systemic growth factor elevation. Liver Int. 2009 Aug; 29(7):1022-30. PMID: 19515220.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    198. Hassan MH, Othman EE, Hornung D, Al-Hendy A. Gene therapy of benign gynecological diseases. Adv Drug Deliv Rev. 2009 Aug 10; 61(10):822-35. PMID: 19446586; PMCID: PMC4477532.
      Citations: 13     Fields:    Translation:HumansAnimals
    199. Hassan M, Zhang D, Salama S, Hamada F, Arafa H, Fouad H, Walker C, Al-Hendy A. Towards fibroid gene therapy: adenovirus-mediated delivery of herpes simplex virus 1 thymidine kinase gene/ganciclovir shrinks uterine leiomyoma in the Eker rat model. Gynecol Obstet Invest. 2009; 68(1):19-32. PMID: 19325244; PMCID: PMC4677717.
      Citations: 11     Fields:    Translation:AnimalsCells
    200. Hassan MH, Salama SA, Zhang D, Arafa HM, Hamada FM, Fouad H, Walker CC, Al-Hendy A. Gene therapy targeting leiomyoma: adenovirus-mediated delivery of dominant-negative estrogen receptor gene shrinks uterine tumors in Eker rat model. Fertil Steril. 2010 Jan; 93(1):239-50. PMID: 19144333; PMCID: PMC2812608.
      Citations: 16     Fields:    Translation:AnimalsCells
    201. Salama SA, Kamel M, Awad M, Nasser AH, Al-Hendy A, Botting S, Arrastia C. Catecholestrogens induce oxidative stress and malignant transformation in human endometrial glandular cells: protective effect of catechol-O-methyltransferase. Int J Cancer. 2008 Sep 15; 123(6):1246-54. PMID: 18566989.
      Citations: 16     Fields:    Translation:HumansCells
    202. Othman EE, Zhu ZB, Curiel DT, Khatoon N, Salem HT, Khalifa EA, Al-Hendy A. Toward gene therapy of endometriosis: transductional and transcriptional targeting of adenoviral vectors to endometriosis cells. Am J Obstet Gynecol. 2008 Aug; 199(2):117.e1-6. PMID: 18674655; PMCID: PMC4191855.
      Citations: 4     Fields:    Translation:HumansCells
    203. Heo MY, Salama SA, Khatoon N, Al-Hendy A, Au WW. Abrogation of estrogen receptor signaling augments cytotoxicity of anticancer drugs on CaSki cervical cancer cells. Anticancer Res. 2008 Jul-Aug; 28(4B):2181-7. PMID: 18751393; PMCID: PMC4477542.
      Citations: 3     Fields:    Translation:HumansCells
    204. Othman Eel-D, Hornung D, Al-Hendy A. Biomarkers of endometriosis. Expert Opin Med Diagn. 2008 Jul; 2(7):741-52. PMID: 23495814.
      Citations: 7     Fields:    
    205. Xu X, Othman Eel-D, Issaq HJ, Hornung D, Al-Hendy A, Veenstra TD. Multiplexed quantitation of endogenous estrogens and estrogen metabolites in human peritoneal fluid. Electrophoresis. 2008 Jun; 29(12):2706-13. PMID: 18512681; PMCID: PMC4297214.
      Citations: 4     Fields:    Translation:Humans
    206. Hassan MH, Eyzaguirre E, Arafa HM, Hamada FM, Salama SA, Al-Hendy A. Memy I: a novel murine model for uterine leiomyoma using adenovirus-enhanced human fibroid explants in severe combined immune deficiency mice. Am J Obstet Gynecol. 2008 Aug; 199(2):156.e1-8. PMID: 18468574; PMCID: PMC4272582.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    207. Othman EE, Al-Hendy A. Molecular genetics and racial disparities of uterine leiomyomas. Best Pract Res Clin Obstet Gynaecol. 2008 Aug; 22(4):589-601. PMID: 18373954; PMCID: PMC4171730.
      Citations: 36     Fields:    Translation:Humans
    208. Azab SS, Salama SA, Hassan MH, Khalifa AE, El-Demerdash E, Fouad H, Al-Hendy A, Abdel-Naim AB. 2-Methoxyestradiol reverses doxorubicin resistance in human breast tumor xenograft. Cancer Chemother Pharmacol. 2008 Oct; 62(5):893-902. PMID: 18253735.
      Citations: 3     Fields:    Translation:HumansAnimals
    209. Azab SS, Salama SA, Abdel-Naim AB, Khalifa AE, El-Demerdash E, Al-Hendy A. 2-Methoxyestradiol and multidrug resistance: can 2-methoxyestradiol chemosensitize resistant breast cancer cells? Breast Cancer Res Treat. 2009 Jan; 113(1):9-19. PMID: 18228136.
      Citations: 5     Fields:    Translation:HumansCells
    210. Hassan MH, Khatoon N, Curiel DT, Hamada FM, Arafa HM, Al-Hendy A. Toward gene therapy of uterine fibroids: targeting modified adenovirus to human leiomyoma cells. Hum Reprod. 2008 Mar; 23(3):514-24. PMID: 18184643.
      Citations: 10     Fields:    Translation:HumansCells
    211. Salih SM, Salama SA, Jamaluddin M, Fadl AA, Blok LJ, Burger CW, Nagamani M, Al-Hendy A. Progesterone-mediated regulation of catechol-O-methyl transferase expression in endometrial cancer cells. Reprod Sci. 2008 Feb; 15(2):210-20. PMID: 18089588.
      Citations: 4     Fields:    Translation:HumansCells
    212. Zhang D, Fouad H, Zoma WD, Salama SA, Wentz MJ, Al-Hendy A. Expression of stem and germ cell markers within nonfollicle structures in adult mouse ovary. Reprod Sci. 2008 Feb; 15(2):139-46. PMID: 18089589.
      Citations: 16     Fields:    Translation:AnimalsCells
    213. Ghadami M, Salama SA, Khatoon N, Chilvers R, Nagamani M, Chedrese PJ, Al-Hendy A. Toward gene therapy of primary ovarian failure: adenovirus expressing human FSH receptor corrects the Finnish C566T mutation. Mol Hum Reprod. 2008 Jan; 14(1):9-15. PMID: 18084009.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    214. Wentz MJ, Shi SQ, Shi L, Salama SA, Harirah HM, Fouad H, Garfield RE, Al-Hendy A. Treatment with an inhibitor of catechol-O-methyltransferase activity reduces preterm birth and impedes cervical resistance to stretch in pregnant rats. Reproduction. 2007 Dec; 134(6):831-9. PMID: 18042640.
      Citations: 4     Fields:    Translation:Animals
    215. Hassan MH, Salama SA, Arafa HM, Hamada FM, Al-Hendy A. Adenovirus-mediated delivery of a dominant-negative estrogen receptor gene in uterine leiomyoma cells abrogates estrogen- and progesterone-regulated gene expression. J Clin Endocrinol Metab. 2007 Oct; 92(10):3949-57. PMID: 17635941.
      Citations: 17     Fields:    Translation:AnimalsCells
    216. Saed GM, Al-Hendy A, Salama SA, Diamond MP. Adenovirus-mediated expression of cyclooxygenase-2 antisense reverse abnormal genetic profile of human adhesion fibroblasts. Fertil Steril. 2008 May; 89(5 Suppl):1455-60. PMID: 17624339.
      Citations: 6     Fields:    Translation:HumansCells
    217. Salih SM, Jamaluddin M, Salama SA, Fadl AA, Nagamani M, Al-Hendy A. Regulation of catechol O-methyltransferase expression in granulosa cells: a potential role for follicular arrest in polycystic ovary syndrome. Fertil Steril. 2008 May; 89(5 Suppl):1414-21. PMID: 17612537.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    218. Salama SA, Jamaluddin M, Kumar R, Hassan MH, Al-Hendy A. Progesterone regulates catechol-O-methyl transferase gene expression in breast cancer cells: distinct effect of progesterone receptor isoforms. J Steroid Biochem Mol Biol. 2007 Nov-Dec; 107(3-5):253-61. PMID: 17689241; PMCID: PMC2254140.
      Citations: 7     Fields:    Translation:HumansCells
    219. Othman Eel-D, Hornung D, Salem HT, Khalifa EA, El-Metwally TH, Al-Hendy A. Serum cytokines as biomarkers for nonsurgical prediction of endometriosis. Eur J Obstet Gynecol Reprod Biol. 2008 Apr; 137(2):240-6. PMID: 17582674.
      Citations: 36     Fields:    Translation:Humans
    220. Salih S, Xu X, Veenstra TD, Duleba AJ, Fouad H, Nagamani M, Al-Hendy A. Lower levels of urinary 2-hydroxyestrogens in polycystic ovary syndrome. J Clin Endocrinol Metab. 2007 Aug; 92(8):3285-91. PMID: 17535988.
      Citations: 4     Fields:    Translation:Humans
    221. Salih SM, Salama SA, Fadl AA, Nagamani M, Al-Hendy A. Expression and cyclic variations of catechol-O-methyl transferase in human endometrial stroma. Fertil Steril. 2008 Sep; 90(3):789-97. PMID: 17418156; PMCID: PMC4477541.
      Citations: 6     Fields:    Translation:HumansCells
    222. Lu F, Longo M, Tamayo E, Maner W, Al-Hendy A, Anderson GD, Hankins GD, Saade GR. The effect of over-expression of sFlt-1 on blood pressure and the occurrence of other manifestations of preeclampsia in unrestrained conscious pregnant mice. Am J Obstet Gynecol. 2007 Apr; 196(4):396.e1-7; discussion 396.e7. PMID: 17403433.
      Citations: 83     Fields:    Translation:Animals
    223. Othman EE, Salama S, Ismail N, Al-Hendy A. Toward gene therapy of endometriosis: adenovirus-mediated delivery of dominant negative estrogen receptor genes inhibits cell proliferation, reduces cytokine production, and induces apoptosis of endometriotic cells. Fertil Steril. 2007 Aug; 88(2):462-71. PMID: 17343855.
      Citations: 14     Fields:    Translation:HumansCells
    224. Au WW, Abdou-Salama S, Al-Hendy A, Sierra-Torres CH. Environmental risk factors for prevention and molecular intervention of cervical cancer. Int J Hyg Environ Health. 2007 Dec; 210(6):671-678. PMID: 17157560.
      Citations: 10     Fields:    Translation:Humans
    225. Wentz MJ, Jamaluddin M, Garfield RE, Al-Hendy A. Regulation of catechol-O-methyltransferase expression in human myometrial cells. Obstet Gynecol. 2006 Dec; 108(6):1439-47. PMID: 17138778; PMCID: PMC4221853.
      Citations: 3     Fields:    Translation:HumansCells
    226. Au WW, Abdou-Salama S, Al-Hendy A. Inhibition of growth of cervical cancer cells using a dominant negative estrogen receptor gene. Gynecol Oncol. 2007 Feb; 104(2):276-80. PMID: 17137618; PMCID: PMC1831876.
      Citations: 9     Fields:    Translation:HumansCells
    227. Salama SA, Nasr AB, Dubey RK, Al-Hendy A. Estrogen metabolite 2-methoxyestradiol induces apoptosis and inhibits cell proliferation and collagen production in rat and human leiomyoma cells: a potential medicinal treatment for uterine fibroids. J Soc Gynecol Investig. 2006 Dec; 13(8):542-50. PMID: 17088081.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    228. Salama SA, Kamel M, Christman G, Wang HQ, Fouad HM, Al-Hendy A. Gene therapy of uterine leiomyoma: adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir treatment inhibits growth of human and rat leiomyoma cells in vitro and in a nude mouse model. Gynecol Obstet Invest. 2007; 63(2):61-70. PMID: 16954695.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    229. Al-Hendy A, Salama SA. Ethnic distribution of estrogen receptor-alpha polymorphism is associated with a higher prevalence of uterine leiomyomas in black Americans. Fertil Steril. 2006 Sep; 86(3):686-93. PMID: 16860797.
      Citations: 42     Fields:    Translation:Humans
    230. Salama SA, Ho SL, Wang HQ, Tenhunen J, Tilgmann C, Al-Hendy A. Hormonal regulation of catechol-O-methyl transferase activity in women with uterine leiomyomas. Fertil Steril. 2006 Jul; 86(1):259-62. PMID: 16730007.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    231. Al-Hendy A, Salama S. Gene therapy and uterine leiomyoma: a review. Hum Reprod Update. 2006 Jul-Aug; 12(4):385-400. PMID: 16603566.
      Citations: 27     Fields:    Translation:HumansAnimals
    232. Al-Hendy A, Salama SA. Catechol-O-methyltransferase polymorphism is associated with increased uterine leiomyoma risk in different ethnic groups. J Soc Gynecol Investig. 2006 Feb; 13(2):136-44. PMID: 16443508.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    233. Al-Hendy A, Lee EJ, Wang HQ, Copland JA. Gene therapy of uterine leiomyomas: adenovirus-mediated expression of dominant negative estrogen receptor inhibits tumor growth in nude mice. Am J Obstet Gynecol. 2004 Nov; 191(5):1621-31. PMID: 15547533.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    234. Young SL, Al-Hendy A, Copland JA. Potential nonhormonal therapeutics for medical treatment of leiomyomas. Semin Reprod Med. 2004 May; 22(2):121-30. PMID: 15164307.
      Citations: 3     Fields:    Translation:Humans
    235. Al-Hendy A, Moshynska O, Saxena A, Feyles V. Association between mutations of the follicle-stimulating-hormone receptor and repeated twinning. Lancet. 2000 Sep 09; 356(9233):914. PMID: 11036902.
      Citations: 4     Fields:    Translation:Humans
    236. Al-Hendy A, Magliocco AM, Al-Tweigeri T, Braileanu G, Crellin N, Li H, Strong T, Curiel D, Chedrese PJ. Ovarian cancer gene therapy: repeated treatment with thymidine kinase in an adenovirus vector and ganciclovir improves survival in a novel immunocompetent murine model. Am J Obstet Gynecol. 2000 Mar; 182(3):553-9. PMID: 10739507.
      Citations: 9     Fields:    Translation:AnimalsCells
    237. Al-Hendy A. Enriching research culture in residency. Am J Obstet Gynecol. 1999 Nov; 181(5 Pt 1):1271. PMID: 10561660.
      Citations:    Fields:    Translation:Humans
    238. Al-Hendy A, Auersperg N. Applying the herpes simplex virus thymidine kinase/ganciclovir approach to ovarian cancer: an effective in vitro drug-sensitization system. Gynecol Obstet Invest. 1997; 43(4):268-75. PMID: 9194627.
      Citations: 9     Fields:    Translation:HumansCells
    239. Hortelano G, Al-Hendy A, Ofosu FA, Chang PL. Delivery of human factor IX in mice by encapsulated recombinant myoblasts: a novel approach towards allogeneic gene therapy of hemophilia B. Blood. 1996 Jun 15; 87(12):5095-103. PMID: 8652822.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    240. Al-Hendy A, Hortelano G, Tannenbaum GS, Chang PL. Growth retardation--an unexpected outcome from growth hormone gene therapy in normal mice with microencapsulated myoblasts. Hum Gene Ther. 1996 Jan; 7(1):61-70. PMID: 8825869.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    241. Skurnik M, Venho R, Toivanen P, al-Hendy A. A novel locus of Yersinia enterocolitica serotype O:3 involved in lipopolysaccharide outer core biosynthesis. Mol Microbiol. 1995 Aug; 17(3):575-94. PMID: 8559076.
      Citations: 35     Fields:    Translation:Cells
    242. al-Hendy A, Hortelano G, Tannenbaum GS, Chang PL. Correction of the growth defect in dwarf mice with nonautologous microencapsulated myoblasts--an alternate approach to somatic gene therapy. Hum Gene Ther. 1995 Feb; 6(2):165-75. PMID: 7734517.
      Citations: 3     Fields:    Translation:AnimalsCells
    243. Zhang L, al-Hendy A, Toivanen P, Skurnik M. Genetic organization and sequence of the rfb gene cluster of Yersinia enterocolitica serotype O:3: similarities to the dTDP-L-rhamnose biosynthesis pathway of Salmonella and to the bacterial polysaccharide transport systems. Mol Microbiol. 1993 Jul; 9(2):309-21. PMID: 7692217.
      Citations: 36     Fields:    Translation:Cells
    244. al-Hendy A, Toivanen P, Skurnik M. Lipopolysaccharide O side chain of Yersinia enterocolitica O:3 is an essential virulence factor in an orally infected murine model. Infect Immun. 1992 Mar; 60(3):870-5. PMID: 1311707; PMCID: PMC257567.
      Citations: 31     Fields:    Translation:AnimalsCells
    245. al-Hendy A, Toivanen P, Skurnik M. Expression cloning of Yersinia enterocolitica O:3 rfb gene cluster in Escherichia coli K12. Microb Pathog. 1991 Jan; 10(1):47-59. PMID: 1857198.
      Citations: 25     Fields:    Translation:Cells
    246. al-Hendy A, Toivanen P, Skurnik M. The effect of growth temperature on the biosynthesis of Yersinia enterocolitica O:3 lipopolysaccharide: temperature regulates the transcription of the rfb but not of the rfa region. Microb Pathog. 1991 Jan; 10(1):81-6. PMID: 1857201.
      Citations: 15     Fields:    Translation:Cells
    247. al-Hendy A, Toivanen P, Skurnik M. Molecular cloning of Yersinia enterocolitica O:3 rfb region: evidence that temperature regulates the rfb region at the transcriptional level. Contrib Microbiol Immunol. 1991; 12:203-9. PMID: 1935091.
      Citations:    Fields:    Translation:Cells
    248. al-Hendy A, Toivanen P, Skurnik M. Rapid method for isolation and staining of bacterial lipopolysaccharide. Microbiol Immunol. 1991; 35(4):331-3. PMID: 1719357.
      Citations: 12     Fields:    Translation:Cells
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