Loading...
The University of Chicago Header Logo
Keywords
Last Name
Institution

Ayman Al-Hendy

TitleProfessor
InstitutionUniversity of Chicago
DepartmentObstetrics and Gynecology
AddressChicago IL 60637
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Afrin S, El Sabeh M, Islam MS, Miyashita-Ishiwata M, Malik M, Catherino WH, Akimzhanov AM, Boehning D, Yang Q, Al-Hendy A, Segars JH, Borahay MA. Simvastatin modulates estrogen signaling in uterine leiomyoma via regulating receptor palmitoylation, trafficking and degradation. Pharmacol Res. 2021 Aug 28; 172:105856. PMID: 34461224.
      View in: PubMed
    2. Chugh RM, Park HS, Esfandyari S, Elsharoud A, Ulin M, Al-Hendy A. Mesenchymal Stem Cell-Conditioned Media Regulate Steroidogenesis and Inhibit Androgen Secretion in a PCOS Cell Model via BMP-2. Int J Mol Sci. 2021 Aug 25; 22(17). PMID: 34502090.
      View in: PubMed
    3. Watts NB, Binkley N, Owens CD, Al-Hendy A, Puscheck EE, Shebley M, Schlaff WD, Simon JA. Bone Mineral Density Changes Associated With Pregnancy, Lactation, and Medical Treatments in Premenopausal Women and Effects Later in Life. J Womens Health (Larchmt). 2021 Aug 25. PMID: 34435897.
      View in: PubMed
    4. Chugh RM, Park HS, El Andaloussi A, Elsharoud A, Esfandyari S, Ulin M, Bakir L, Aboalsoud A, Ali M, Ashour D, Igboeli P, Ismail N, McAllister J, Al-Hendy A. Mesenchymal stem cell therapy ameliorates metabolic dysfunction and restores fertility in a PCOS mouse model through interleukin-10. Stem Cell Res Ther. 2021 07 07; 12(1):388. PMID: 34233746.
      View in: PubMed
    5. Cetin E, Siblini H, Al-Hendy A. What is the Mechanism of Poor Endometrial Proliferation in Patients with Unexplained Infertility After Clomiphene Citrate Treatment? J Clin Endocrinol Metab. 2021 Jun 30. PMID: 34192332.
      View in: PubMed
    6. Al-Hendy A, Ku SY. Reproductive Tract Tissue/Organ Engineering and Regenerative Medicine for Reproduction. Reprod Sci. 2021 06; 28(6):1571-1572. PMID: 33905084.
      View in: PubMed
    7. Navarro A, Bariani MV, Yang Q, Al-Hendy A. Understanding the Impact of Uterine Fibroids on Human Endometrium Function. Front Cell Dev Biol. 2021; 9:633180. PMID: 34113609.
      View in: PubMed
    8. Ulin M, Cetin E, Hobeika E, Chugh RM, Park HS, Esfandyari S, Al-Hendy A. Human Mesenchymal Stem Cell Therapy and Other Novel Treatment Approaches for Premature Ovarian Insufficiency. Reprod Sci. 2021 06; 28(6):1688-1696. PMID: 33956339.
      View in: PubMed
    9. Bateman NW, Tarney CM, Abulez T, Soltis AR, Zhou M, Conrads K, Litzi T, Oliver J, Hood B, Driggers P, Viollet C, Dalgard C, Wilkerson M, Catherino W, Hamilton CA, Darcy KM, Casablanca Y, Al-Hendy A, Segars J, Conrads TP, Larry Maxwell G. Proteogenomic landscape of uterine leiomyomas from hereditary leiomyomatosis and renal cell cancer patients. Sci Rep. 2021 Apr 30; 11(1):9371. PMID: 33931688.
      View in: PubMed
    10. Ciebiera M, Esfandyari S, Siblini H, Prince L, Elkafas H, Wojtyla C, Al-Hendy A, Ali M. Nutrition in Gynecological Diseases: Current Perspectives. Nutrients. 2021 Apr 02; 13(4). PMID: 33918317.
      View in: PubMed
    11. Park HS, Chugh RM, El Andaloussi A, Hobeika E, Esfandyari S, Elsharoud A, Ulin M, Garcia N, Bilal M, Al-Hendy A. Human BM-MSC secretome enhances human granulosa cell proliferation and steroidogenesis and restores ovarian function in primary ovarian insufficiency mouse model. Sci Rep. 2021 Feb 25; 11(1):4525. PMID: 33633319.
      View in: PubMed
    12. Esfandyari S, Elkafas H, Chugh RM, Park HS, Navarro A, Al-Hendy A. Exosomes as Biomarkers for Female Reproductive Diseases Diagnosis and Therapy. Int J Mol Sci. 2021 Feb 22; 22(4). PMID: 33671587.
      View in: PubMed
    13. Al-Hendy A, Lukes AS, Poindexter AN, Venturella R, Villarroel C, Critchley HOD, Li Y, McKain L, Arjona Ferreira JC, Langenberg AGM, Wagman RB, Stewart EA. Treatment of Uterine Fibroid Symptoms with Relugolix Combination Therapy. N Engl J Med. 2021 02 18; 384(7):630-642. PMID: 33596357.
      View in: PubMed
    14. Park HS, Chugh RM, Elsharoud A, Ulin M, Esfandyari S, Aboalsoud A, Bakir L, Al-Hendy A. Safety of Intraovarian Injection of Human Mesenchymal Stem Cells in a Premature Ovarian Insufficiency Mouse Model. Cell Transplant. 2021 Jan-Dec; 30:963689720988502. PMID: 33593078.
      View in: PubMed
    15. Garcia N, Al-Hendy A, Baracat EC, Carvalho KC, Yang Q. Targeting Hedgehog Pathway and DNA Methyltransferases in Uterine Leiomyosarcoma Cells. Cells. 2020 12 31; 10(1). PMID: 33396427.
      View in: PubMed
    16. Elsharoud A, Brakta S, Elhusseini H, Al-Hendy A. A presentation of ovarian fibrothecoma in a middle-aged female with recurrent massive ascites and postmenopausal bleeding: A case report. SAGE Open Med Case Rep. 2020; 8:2050313X20974222. PMID: 33425356.
      View in: PubMed
    17. Bariani MV, Rangaswamy R, Siblini H, Yang Q, Al-Hendy A, Zota AR. The role of endocrine-disrupting chemicals in uterine fibroid pathogenesis. Curr Opin Endocrinol Diabetes Obes. 2020 12; 27(6):380-387. PMID: 33044243.
      View in: PubMed
    18. Leppert PC, Al-Hendy A, Baird DD, Bulun S, Catherino W, Dixon D, Ducharme M, Harmon QE, Jayes FL, Paul E, Perucho AM, Segars J, Simón C, Stewart EA, Teixeira J, Tinelli A, Tschumperlin D, Zota AR. Summary of the Proceedings of the Basic Science of Uterine Fibroids Meeting: New Developments February 28, 2020. F S Sci. 2021 Feb; 2(1):88-100. PMID: 34124698.
      View in: PubMed
    19. Ciebiera M, Ali M, Prince L, Zgliczynski S, Jakiel G, Al-Hendy A. The Significance of Measuring Vitamin D Serum Levels in Women with Uterine Fibroids. Reprod Sci. 2021 08; 28(8):2098-2109. PMID: 33108619.
      View in: PubMed
    20. Garcia N, Ulin M, Al-Hendy A, Yang Q. The Role of Hedgehog Pathway in Female Cancers. J Cancer Sci Clin Ther. 2020; 4(4):487-498. PMID: 33179013.
      View in: PubMed
    21. Esfandyari S, Chugh RM, Park HS, Hobeika E, Ulin M, Al-Hendy A. Mesenchymal Stem Cells as a Bio Organ for Treatment of Female Infertility. Cells. 2020 10 08; 9(10). PMID: 33050021.
      View in: PubMed
    22. Cetin E, Al-Hendy A, Ciebiera M. Non-hormonal mediators of uterine fibroid growth. Curr Opin Obstet Gynecol. 2020 10; 32(5):361-370. PMID: 32739973.
      View in: PubMed
    23. Ciebiera M, Ali M, Zgliczynska M, Skrzypczak M, Al-Hendy A. Vitamins and Uterine Fibroids: Current Data on Pathophysiology and Possible Clinical Relevance. Int J Mol Sci. 2020 Aug 01; 21(15). PMID: 32752274.
      View in: PubMed
    24. Al-Hendy A, Bradley L, Owens CD, Wang H, Barnhart KT, Feinberg E, Schlaff WD, Puscheck EE, Wang A, Gillispie V, Hurtado S, Muneyyirci-Delale O, Archer DF, Carr BR, Simon JA, Stewart EA. Predictors of response for elagolix with add-back therapy in women with heavy menstrual bleeding associated with uterine fibroids. Am J Obstet Gynecol. 2021 01; 224(1):72.e1-72.e50. PMID: 32702363.
      View in: PubMed
    25. Igboeli P, El Andaloussi A, Sheikh U, Takala H, ElSharoud A, McHugh A, Gavrilova-Jordan L, Levy S, Al-Hendy A. Intraovarian injection of autologous human mesenchymal stem cells increases estrogen production and reduces menopausal symptoms in women with premature ovarian failure: two case reports and a review of the literature. J Med Case Rep. 2020 Jul 18; 14(1):108. PMID: 32680541.
      View in: PubMed
    26. Elkafas H, Ali M, Elmorsy E, Kamel R, Thompson WE, Badary O, Al-Hendy A, Yang Q. Vitamin D3 Ameliorates DNA Damage Caused by Developmental Exposure to Endocrine Disruptors in the Uterine Myometrial Stem Cells of Eker Rats. Cells. 2020 06 12; 9(6). PMID: 32545544.
      View in: PubMed
    27. Ali M, Esfandyari S, Al-Hendy A. Evolving role of microRNAs in uterine fibroid pathogenesis: filling the gap! Fertil Steril. 2020 06; 113(6):1167-1168. PMID: 32482253.
      View in: PubMed
    28. Simon JA, Al-Hendy A, Archer DF, Barnhart KT, Bradley LD, Carr BR, Dayspring T, Feinberg EC, Gillispie V, Hurtado S, Kim J, Liu R, Owens CD, Muneyyirci-Delale O, Wang A, Watts NB, Schlaff WD. Elagolix Treatment for Up to 12 Months in Women With Heavy Menstrual Bleeding and Uterine Leiomyomas. Obstet Gynecol. 2020 06; 135(6):1313-1326. PMID: 32459423.
      View in: PubMed
    29. Ciebiera M, Ali M, Prince L, Jackson-Bey T, Atabiekov I, Zgliczynski S, Al-Hendy A. The Evolving Role of Natural Compounds in the Medical Treatment of Uterine Fibroids. J Clin Med. 2020 May 14; 9(5). PMID: 32423112.
      View in: PubMed
    30. Ali M, Shahin SM, Sabri NA, Al-Hendy A, Yang Q. Activation of ß-Catenin Signaling and its Crosstalk With Estrogen and Histone Deacetylases in Human Uterine Fibroids. J Clin Endocrinol Metab. 2020 04 01; 105(4). PMID: 31761932.
      View in: PubMed
    31. Small B, Millard CEF, Kisanga EP, Burman A, Anam A, Flannery C, Al-Hendy A, Whirledge S. The Selective Progesterone Receptor Modulator Ulipristal Acetate Inhibits the Activity of the Glucocorticoid Receptor. J Clin Endocrinol Metab. 2020 03 01; 105(3). PMID: 31665442.
      View in: PubMed
    32. Ulin M, Ali M, Chaudhry ZT, Al-Hendy A, Yang Q. Uterine fibroids in menopause and perimenopause. Menopause. 2020 02; 27(2):238-242. PMID: 31834160.
      View in: PubMed
    33. Schlaff WD, Ackerman RT, Al-Hendy A, Archer DF, Barnhart KT, Bradley LD, Carr BR, Feinberg EC, Hurtado SM, Kim J, Liu R, Mabey RG, Owens CD, Poindexter A, Puscheck EE, Rodriguez-Ginorio H, Simon JA, Soliman AM, Stewart EA, Watts NB, Muneyyirci-Delale O. Elagolix for Heavy Menstrual Bleeding in Women with Uterine Fibroids. N Engl J Med. 2020 01 23; 382(4):328-340. PMID: 31971678.
      View in: PubMed
    34. Shalaby S, Khater M, Laknaur A, Arbab A, Al-Hendy A. Molecular Bio-Imaging Probe for Non-Invasive Differentiation Between Human Leiomyoma Versus Leiomyosarcoma. Reprod Sci. 2020 02; 27(2):644-654. PMID: 31925772.
      View in: PubMed
    35. El Andaloussi A, Al-Hendy A, Ismail N, Boyer TG, Halder SK. Introduction of Somatic Mutation in MED12 Induces Wnt4/ß-Catenin and Disrupts Autophagy in Human Uterine Myometrial Cell. Reprod Sci. 2020 03; 27(3):823-832. PMID: 32046450.
      View in: PubMed
    36. Ku SY, Al-Hendy A. Vision 20/20 for the Second Leap of Reproductive Sciences. Reprod Sci. 2020 01; 27(1):1-2. PMID: 32030671.
      View in: PubMed
    37. Takala H, Al-Hendy A, Yang Q. Neurotrimin: a novel neural cell adhesion molecule correlating with uterine fibroid phenotype. Fertil Steril. 2020 01; 113(1):83-84. PMID: 32033733.
      View in: PubMed
    38. Takala H, Yang Q, El Razek AMA, Ali M, Al-Hendy A. Alcohol Consumption and Risk of Uterine Fibroids. Curr Mol Med. 2020; 20(4):247-258. PMID: 31612831.
      View in: PubMed
    39. Ali M, Prince L, Al-Hendy A. Vitamin D and uterine fibroids: preclinical evidence is in; time for an overdue clinical study! Fertil Steril. 2020 01; 113(1):89-90. PMID: 32033736.
      View in: PubMed
    40. Park HS, Ashour D, Elsharoud A, Chugh RM, Ismail N, El Andaloussi A, Al-Hendy A. Towards Cell free Therapy of Premature Ovarian Insufficiency: Human Bone Marrow Mesenchymal Stem Cells Secretome Enhances Angiogenesis in Human Ovarian Microvascular Endothelial Cells. HSOA J Stem Cells Res Dev Ther. 2019; 5(2). PMID: 32494757.
      View in: PubMed
    41. Igboeli P, Walker W, McHugh A, Sultan A, Al-Hendy A. Burden of Uterine Fibroids: An African Perspective, A Call for Action and Opportunity for Intervention. Curr Opin Gynecol Obstet. 2019; 2(1):287-294. PMID: 32647835.
      View in: PubMed
    42. Omar M, Laknaur A, Al-Hendy A, Yang Q. Myometrial progesterone hyper-responsiveness associated with increased risk of human uterine fibroids. BMC Womens Health. 2019 07 09; 19(1):92. PMID: 31288815.
      View in: PubMed
    43. Cao T, Jiang Y, Wang Z, Zhang N, Al-Hendy A, Mamillapalli R, Kallen AN, Kodaman P, Taylor HS, Li D, Huang Y. H19 lncRNA identified as a master regulator of genes that drive uterine leiomyomas. Oncogene. 2019 07; 38(27):5356-5366. PMID: 31089260.
      View in: PubMed
    44. Ulin M, Al-Hendy A, Yang Q. Targeting the transforming growth factor-ß pathway: a novel mechanism of ulipristal acetate action against uterine fibroids. Fertil Steril. 2019 04; 111(4):683-684. PMID: 30929728.
      View in: PubMed
    45. Mohamed SA, Shalaby S, Brakta S, Elam L, Elsharoud A, Al-Hendy A. Umbilical Cord Blood Mesenchymal Stem Cells as an Infertility Treatment for Chemotherapy Induced Premature Ovarian Insufficiency. Biomedicines. 2019 Jan 18; 7(1). PMID: 30669278.
      View in: PubMed
    46. Ali M, Al-Hendy A, Yang Q. Vitamin D, a promising natural compound with anti-uterine fibroid characteristics. Fertil Steril. 2019 02; 111(2):268-269. PMID: 30598168.
      View in: PubMed
    47. Ali M, Shahin SM, Sabri NA, Al-Hendy A, Yang Q. 1,25 Dihydroxyvitamin D3 Enhances the Antifibroid Effects of Ulipristal Acetate in Human Uterine Fibroids. Reprod Sci. 2019 06; 26(6):812-828. PMID: 30514160.
      View in: PubMed
    48. Ali M, Jackson-Bey T, Al-Hendy A. Simvastatin and uterine fibroids: opportunity for a novel therapeutic option. Fertil Steril. 2018 12; 110(7):1272-1273. PMID: 30503124.
      View in: PubMed
    49. Brakta S, Mas A, Al-Hendy A. The ontogeny of myometrial stem cells in OCT4-GFP transgenic mouse model. Stem Cell Res Ther. 2018 11 29; 9(1):333. PMID: 30486855.
      View in: PubMed
    50. Ali M, Shahin SM, Sabri NA, Al-Hendy A, Yang Q. Hypovitaminosis D exacerbates the DNA damage load in human uterine fibroids, which is ameliorated by vitamin D3 treatment. Acta Pharmacol Sin. 2019 Jul; 40(7):957-970. PMID: 30478352.
      View in: PubMed
    51. Atabiekov I, Hobeika E, Sheikh U, El Andaloussi A, Al-Hendy A. The Role of Gene Therapy in Premature Ovarian Insufficiency Management. Biomedicines. 2018 Nov 01; 6(4). PMID: 30388808.
      View in: PubMed
    52. Park MJ, Shen H, Kim NH, Gao F, Failor C, Knudtson JF, McLaughlin J, Halder SK, Heikkinen TA, Vahteristo P, Al-Hendy A, Schenken RS, Boyer TG. Mediator Kinase Disruption in MED12-Mutant Uterine Fibroids From Hispanic Women of South Texas. J Clin Endocrinol Metab. 2018 11 01; 103(11):4283-4292. PMID: 30099503.
      View in: PubMed
    53. Carr BR, Stewart EA, Archer DF, Al-Hendy A, Bradley L, Watts NB, Diamond MP, Gao J, Owens CD, Chwalisz K, Duan WR, Soliman AM, Dufek MB, Simon JA. Elagolix Alone or With Add-Back Therapy in Women With Heavy Menstrual Bleeding and Uterine Leiomyomas: A Randomized Controlled Trial. Obstet Gynecol. 2018 11; 132(5):1252-1264. PMID: 30303923.
      View in: PubMed
    54. Prusinski Fernung LE, Yang Q, Sakamuro D, Kumari A, Mas A, Al-Hendy A. Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering DNA repair in myometrial stem cells. Biol Reprod. 2018 10 01; 99(4):735-748. PMID: 29688260.
      View in: PubMed
    55. Marsh EE, Al-Hendy A, Kappus D, Galitsky A, Stewart EA, Kerolous M. Burden, Prevalence, and Treatment of Uterine Fibroids: A Survey of U.S. Women. J Womens Health (Larchmt). 2018 11; 27(11):1359-1367. PMID: 30230950.
      View in: PubMed
    56. Yang Q, Ali M, El Andaloussi A, Al-Hendy A. The emerging spectrum of early life exposure-related inflammation and epigenetic therapy. Cancer Stud Mol Med. 2018 Nov; 4(1):13-23. PMID: 30474062.
      View in: PubMed
    57. El Andaloussi A, Igboeli P, Amer A, Al-Hendy A. Intravenous Infusion of Nucleated Peripheral Blood Cells Restores Fertility in Mice with Chemotherapy-Induced Premature Ovarian Failure. Biomedicines. 2018 Sep 15; 6(3). PMID: 30223591.
      View in: PubMed
    58. Elhusseini H, Elkafas H, Abdelaziz M, Halder S, Atabiekov I, Eziba N, Ismail N, El Andaloussi A, Al-Hendy A. Diet-induced vitamin D deficiency triggers inflammation and DNA damage profile in murine myometrium. Int J Womens Health. 2018; 10:503-514. PMID: 30214319.
      View in: PubMed
    59. Ali M, Al-Hendy A. Uterine fibroid therapy: the pharmacokinetic considerations. Expert Opin Drug Metab Toxicol. 2018 Sep; 14(9):887-889. PMID: 30058386.
      View in: PubMed
    60. Prusinski Fernung LE, Jones K, Mas A, Kleven D, Waller JL, Al-Hendy A. Expanding upon the Human Myometrial Stem Cell Hypothesis and the Role of Race, Hormones, Age, and Parity in a Profibroid Environment. Am J Pathol. 2018 10; 188(10):2293-2306. PMID: 30075150.
      View in: PubMed
    61. Prusinski Fernung LE, Al-Hendy A, Yang Q. A Preliminary Study: Human Fibroid Stro-1+/CD44+ Stem Cells Isolated From Uterine Fibroids Demonstrate Decreased DNA Repair and Genomic Integrity Compared to Adjacent Myometrial Stro-1+/CD44+ Cells. Reprod Sci. 2019 05; 26(5):619-638. PMID: 29954254.
      View in: PubMed
    62. Habib S, El Andaloussi A, Elmasry K, Handoussa A, Azab M, Elsawey A, Al-Hendy A, Ismail N. PDL-1 Blockade Prevents T Cell Exhaustion, Inhibits Autophagy, and Promotes Clearance of Leishmania donovani. Infect Immun. 2018 06; 86(6). PMID: 29610255.
      View in: PubMed
    63. Yang Q, Al-Hendy A. The Emerging Role of p27 in Development of Diseases. Cancer Stud Mol Med. 2018 Nov; 4(1):e1-e3. PMID: 30474063.
      View in: PubMed
    64. Yang Q, Al-Hendy A. Non-coding RNAs: an important regulatory mechanism in pathogenesis of uterine fibroids. Fertil Steril. 2018 05; 109(5):802-803. PMID: 29778379.
      View in: PubMed
    65. Simon JA, Catherino W, Segars JH, Blakesley RE, Chan A, Sniukiene V, Al-Hendy A. Ulipristal Acetate for Treatment of Symptomatic Uterine Leiomyomas: A Randomized Controlled Trial. Obstet Gynecol. 2018 03; 131(3):431-439. PMID: 29420395.
      View in: PubMed
    66. Park MJ, Shen H, Spaeth JM, Tolvanen JH, Failor C, Knudtson JF, McLaughlin J, Halder SK, Yang Q, Bulun SE, Al-Hendy A, Schenken RS, Aaltonen LA, Boyer TG. Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19. J Biol Chem. 2018 03 30; 293(13):4870-4882. PMID: 29440396.
      View in: PubMed
    67. Ali M, Chaudhry ZT, Al-Hendy A. Successes and failures of uterine leiomyoma drug discovery. Expert Opin Drug Discov. 2018 02; 13(2):169-177. PMID: 29254389.
      View in: PubMed
    68. Segars JH, Al-Hendy A. Uterine Leiomyoma: New Perspectives on an Old Disease. Semin Reprod Med. 2017 11; 35(6):471-472. PMID: 29100233.
      View in: PubMed
    69. Al-Hendy A, Myers ER, Stewart E. Uterine Fibroids: Burden and Unmet Medical Need. Semin Reprod Med. 2017 11; 35(6):473-480. PMID: 29100234.
      View in: PubMed
    70. El Andaloussi A, Chaudhry Z, Al-Hendy A, Ismail N. Uterine Fibroids: Bridging Genomic Defects and Chronic Inflammation. Semin Reprod Med. 2017 11; 35(6):494-498. PMID: 29100237.
      View in: PubMed
    71. Elkafas H, Qiwei Y, Al-Hendy A. Origin of Uterine Fibroids: Conversion of Myometrial Stem Cells to Tumor-Initiating Cells. Semin Reprod Med. 2017 11; 35(6):481-486. PMID: 29100235.
      View in: PubMed
    72. Abdelaziz M, Eziba N, Sharma S, Kleven D, Al-Hendy A. Cervical superficial myofibroblastoma: Case report and review of the literature. SAGE Open Med Case Rep. 2017; 5:2050313X17726936. PMID: 28904795.
      View in: PubMed
    73. Ali M, Al-Hendy A. Selective progesterone receptor modulators for fertility preservation in women with symptomatic uterine fibroids. Biol Reprod. 2017 Sep 01; 97(3):337-352. PMID: 29025038.
      View in: PubMed
    74. Andaloussi AE, Habib S, Soylemes G, Laknaur A, Elhusseini H, Al-Hendy A, Ismail N. Defective expression of ATG4D abrogates autophagy and promotes growth in human uterine fibroids. Cell Death Discov. 2017; 3:17041. PMID: 28815060.
      View in: PubMed
    75. Mohamed SA, El Andaloussi A, Al-Hendy A, Menon R, Behnia F, Schulkin J, Power ML. Vitamin D and corticotropin-releasing hormone in term and preterm birth: potential contributions to preterm labor and birth outcome. J Matern Fetal Neonatal Med. 2018 Nov; 31(21):2911-2917. PMID: 28780891.
      View in: PubMed
    76. Fletcher NM, Abusamaan MS, Memaj I, Saed MG, Al-Hendy A, Diamond MP, Saed GM. Oxidative stress: a key regulator of leiomyoma cell survival. Fertil Steril. 2017 06; 107(6):1387-1394.e1. PMID: 28483502.
      View in: PubMed
    77. Mohamed SA, Shalaby SM, Abdelaziz M, Brakta S, Hill WD, Ismail N, Al-Hendy A. Human Mesenchymal Stem Cells Partially Reverse Infertility in Chemotherapy-Induced Ovarian Failure. Reprod Sci. 2018 01; 25(1):51-63. PMID: 28460567.
      View in: PubMed
    78. Al-Hendy A, Laknaur A, Diamond MP, Ismail N, Boyer TG, Halder SK. Silencing Med12 Gene Reduces Proliferation of Human Leiomyoma Cells Mediated via Wnt/ß-Catenin Signaling Pathway. Endocrinology. 2017 03 01; 158(3):592-603. PMID: 27967206.
      View in: PubMed
    79. Mas A, Prusinski L, Yang Q, Diaz-Gimeno P, Stone L, Diamond MP, Simón C, Al-Hendy A. Role of Stro1+/CD44+ stem cells in myometrial physiology and uterine remodeling during pregnancy. Biol Reprod. 2017 01 01; 96(1):70-80. PMID: 28395335.
      View in: PubMed
    80. Yang Q, Al-Hendy A. Developmental Environmental Exposure Alters the Epigenetic Features of Myometrial Stem Cells. Gynecol Obstet Res. 2016 Dec; 3(2):e1-e4. PMID: 28626795.
      View in: PubMed
    81. Borahay MA, Asoglu MR, Mas A, Adam S, Kilic GS, Al-Hendy A. Estrogen Receptors and Signaling in Fibroids: Role in Pathobiology and Therapeutic Implications. Reprod Sci. 2017 09; 24(9):1235-1244. PMID: 27872195.
      View in: PubMed
    82. Mas A, Stone L, O'Connor PM, Yang Q, Kleven D, Simon C, Walker CL, Al-Hendy A. Developmental Exposure to Endocrine Disruptors Expands Murine Myometrial Stem Cell Compartment as a Prerequisite to Leiomyoma Tumorigenesis. Stem Cells. 2017 03; 35(3):666-678. PMID: 27739139.
      View in: PubMed
    83. Chuang TY, Min J, Wu HL, McCrary C, Layman LC, Diamond MP, Azziz R, Al-Hendy A, Chen YH. Berberine Inhibits Uterine Leiomyoma Cell Proliferation via Downregulation of Cyclooxygenase 2 and Pituitary Tumor-Transforming Gene 1. Reprod Sci. 2017 07; 24(7):1005-1013. PMID: 27799459.
      View in: PubMed
    84. Halder S, Al-Hendy A. Hypovitaminosis D and high serum transforming growth factor beta-3: important biomarkers for uterine fibroids risk. Fertil Steril. 2016 12; 106(7):1648-1649. PMID: 27793369.
      View in: PubMed
    85. Atta HM, Al-Hendy AA, Abdel Raheim SR, Abdel-Ghany H, Nasif KA, Abdellah AM, Zenhom NM, Kamel HS. Modified Adenovirus Reduces De Novo Peritoneal Adhesions in Rats and Limits Off-Target Transfection. Role of EZH2 in Adhesion Formation. J Invest Surg. 2017 Apr; 30(2):78-87. PMID: 27690696.
      View in: PubMed
    86. Latif E, Adam S, Rungruang B, Al-Hendy A, Diamond MP, Rotem E, Cannell J, Browne PC. Use of uterine artery embolization to prevent peripartum hemorrhage of placental abruption with fetal demise & severe DIC. J Neonatal Perinatal Med. 2016 Sep 16; 9(3):325-31. PMID: 27589544.
      View in: PubMed
    87. Mohamed SA, Al-Hendy A, Schulkin J, Power ML. Opinions and Practice of US-Based Obstetrician-Gynecologists regarding Vitamin D Screening and Supplementation of Pregnant Women. J Pregnancy. 2016; 2016:1454707. PMID: 27648304.
      View in: PubMed
    88. Katz TA, Yang Q, Treviño LS, Walker CL, Al-Hendy A. Endocrine-disrupting chemicals and uterine fibroids. Fertil Steril. 2016 09 15; 106(4):967-77. PMID: 27553264.
      View in: PubMed
    89. Othman ER, Elgamal DA, Refaiy AM, Abdelaal II, Abdel-Mola AF, Al-Hendy A. Identification and potential role of telocytes in human uterine leiomyoma. Contracept Reprod Med. 2016; 1:12. PMID: 29201401.
      View in: PubMed
    90. Prusinski L, Al-Hendy A, Yang Q. Developmental exposure to endocrine disrupting chemicals alters the epigenome: Identification of reprogrammed targets. Gynecol Obstet Res. 2016 Jul; 3(1):1-6. PMID: 27478869.
      View in: PubMed
    91. Yang Q, Diamond MP, Al-Hendy A. Converting of Myometrial Stem Cells to Tumor-Initiating Cells: Mechanism of Uterine Fibroid Development. Cell Stem Cells Regen Med. 2016 Apr; 2(1). PMID: 28042616.
      View in: PubMed
    92. Yang Q, Laknaur A, Elam L, Ismail N, Gavrilova-Jordan L, Lue J, Diamond MP, Al-Hendy A. Identification of Polycomb Group Protein EZH2-Mediated DNA Mismatch Repair Gene MSH2 in Human Uterine Fibroids. Reprod Sci. 2016 10; 23(10):1314-25. PMID: 27036951.
      View in: PubMed
    93. Shalaby SM, Khater MK, Perucho AM, Mohamed SA, Helwa I, Laknaur A, Lebedyeva I, Liu Y, Diamond MP, Al-Hendy AA. Magnetic nanoparticles as a new approach to improve the efficacy of gene therapy against differentiated human uterine fibroid cells and tumor-initiating stem cells. Fertil Steril. 2016 06; 105(6):1638-1648.e8. PMID: 27020169.
      View in: PubMed
    94. Yang Q, Diamond MP, Al-Hendy A. Early Life Adverse Environmental Exposures Increase the Risk of Uterine Fibroid Development: Role of Epigenetic Regulation. Front Pharmacol. 2016; 7:40. PMID: 26973527.
      View in: PubMed
    95. Othman ER, Hornung D, Hussein M, Abdelaal II, Sayed AA, Fetih AN, Al-Hendy A. Soluble tumor necrosis factor-alpha receptors in the serum of endometriosis patients. Eur J Obstet Gynecol Reprod Biol. 2016 May; 200:1-5. PMID: 26963895.
      View in: PubMed
    96. Yang Q, Nair S, Laknaur A, Ismail N, Diamond MP, Al-Hendy A. The Polycomb Group Protein EZH2 Impairs DNA Damage Repair Gene Expression in Human Uterine Fibroids. Biol Reprod. 2016 Mar; 94(3):69. PMID: 26888970.
      View in: PubMed
    97. Abdelaziz M, Sherif L, ElKhiary M, Nair S, Shalaby S, Mohamed S, Eziba N, El-Lakany M, Curiel D, Ismail N, Diamond MP, Al-Hendy A. Targeted Adenoviral Vector Demonstrates Enhanced Efficacy for In Vivo Gene Therapy of Uterine Leiomyoma. Reprod Sci. 2016 Apr; 23(4):464-74. PMID: 26884457.
      View in: PubMed
    98. Othman ER, Curiel DT, Hussein M, Abdelaal II, Fetih AN, Al-Hendy A. Enhancing Adenoviral-Mediated Gene Transfer and Expression to Endometrial Cells. Reprod Sci. 2016 08; 23(8):1109-15. PMID: 26865542.
      View in: PubMed
    99. Mohamed SA, Al-Hendy A, Ghamande S, Chaffin J, Browne P. Atypical Presentations of Molar Pregnancy: Diagnostic Roles of Imaging, ß-Human Chorionic Gonadotropin Measurement, and p57 Immunostaining. J Ultrasound Med. 2016 Mar; 35(3):643-9. PMID: 26860483.
      View in: PubMed
    100. Yang Q, Diamond MP, Al-Hendy A. The emerging role of extracellular vesicle-derived miRNAs: implication in cancer progression and stem cell related diseases. J Clin Epigenet. 2016; 2(1). PMID: 27099870.
      View in: PubMed
    101. Al-Hendy A, Diamond MP, Boyer TG, Halder SK. Vitamin D3 Inhibits Wnt/ß-Catenin and mTOR Signaling Pathways in Human Uterine Fibroid Cells. J Clin Endocrinol Metab. 2016 04; 101(4):1542-51. PMID: 26820714.
      View in: PubMed
    102. Parker W, Berek JS, Pritts E, Olive D, Kaunitz AM, Chalas E, Clarke-Pearson D, Goff B, Bristow R, Taylor HS, Farias-Eisner R, Fader AN, Maxwell GL, Goodwin SC, Love S, Gibbons WE, Foshag LJ, Leppert PC, Norsigian J, Nager CW, Johnson T, Guzick DS, As-Sanie S, Paulson RJ, Farquhar C, Bradley L, Scheib SA, Bilchik AJ, Rice LW, Dionne C, Jacoby A, Ascher-Walsh C, Kilpatrick SJ, Adamson GD, Siedhoff M, Israel R, Paraiso MF, Frumovitz MM, Lurain JR, Al-Hendy A, Benrubi GI, Raman SS, Kho RM, Anderson TL, Reynolds RK, DeLancey J. An Open Letter to the Food and Drug Administration Regarding the Use of Morcellation Procedures in Women Having Surgery for Presumed Uterine Myomas. J Minim Invasive Gynecol. 2016 Mar-Apr; 23(3):303-8. PMID: 26773577.
      View in: PubMed
    103. Laknaur A, Foster TL, Bobb LE, Ramesh A, Ladson GM, Hood DB, Al-Hendy A, Thota C. Altered expression of histone deacetylases, inflammatory cytokines and contractile-associated factors in uterine myometrium of Long Evans rats gestationally exposed to benzo[a]pyrene. J Appl Toxicol. 2016 Jun; 36(6):827-35. PMID: 26358852.
      View in: PubMed
    104. Brakta S, Diamond JS, Al-Hendy A, Diamond MP, Halder SK. Role of vitamin D in uterine fibroid biology. Fertil Steril. 2015 Sep; 104(3):698-706. PMID: 26079694.
      View in: PubMed
    105. Mas A, Nair S, Laknaur A, Simón C, Diamond MP, Al-Hendy A. Stro-1/CD44 as putative human myometrial and fibroid stem cell markers. Fertil Steril. 2015 Jul; 104(1):225-34.e3. PMID: 25989979.
      View in: PubMed
    106. Yang Q, Mas A, Diamond MP, Al-Hendy A. The Mechanism and Function of Epigenetics in Uterine Leiomyoma Development. Reprod Sci. 2016 Feb; 23(2):163-75. PMID: 25922306.
      View in: PubMed
    107. Borahay MA, Al-Hendy A, Kilic GS, Boehning D. Signaling Pathways in Leiomyoma: Understanding Pathobiology and Implications for Therapy. Mol Med. 2015 Apr 13; 21:242-56. PMID: 25879625.
      View in: PubMed
    108. Borahay MA, Vincent K, Motamedi M, Sbrana E, Kilic GS, Al-Hendy A, Boehning D. Novel effects of simvastatin on uterine fibroid tumors: in vitro and patient-derived xenograft mouse model study. Am J Obstet Gynecol. 2015 Aug; 213(2):196.e1-8. PMID: 25840272.
      View in: PubMed
    109. Nothnick WB, Al-Hendy A, Lue JR. Circulating Micro-RNAs as Diagnostic Biomarkers for Endometriosis: Privation and Promise. J Minim Invasive Gynecol. 2015 Jul-Aug; 22(5):719-26. PMID: 25757811.
      View in: PubMed
    110. Wu HL, Chuang TY, Al-Hendy A, Diamond MP, Azziz R, Chen YH. Berberine inhibits the proliferation of human uterine leiomyoma cells. Fertil Steril. 2015 Apr; 103(4):1098-106. PMID: 25682924.
      View in: PubMed
    111. Al-Hendy A, Diamond MP, El-Sohemy A, Halder SK. 1,25-dihydroxyvitamin D3 regulates expression of sex steroid receptors in human uterine fibroid cells. J Clin Endocrinol Metab. 2015 Apr; 100(4):E572-82. PMID: 25625804.
      View in: PubMed
    112. Atta H, El-Rehany M, Hammam O, Abdel-Ghany H, Ramzy M, Roderfeld M, Roeb E, Al-Hendy A, Raheim SA, Allam H, Marey H. Mutant MMP-9 and HGF gene transfer enhance resolution of CCl4-induced liver fibrosis in rats: role of ASH1 and EZH2 methyltransferases repression. PLoS One. 2014; 9(11):e112384. PMID: 25380300.
      View in: PubMed
    113. Borahay MA, Kilic GS, Yallampalli C, Snyder RR, Hankins GD, Al-Hendy A, Boehning D. Simvastatin potently induces calcium-dependent apoptosis of human leiomyoma cells. J Biol Chem. 2014 Dec 19; 289(51):35075-86. PMID: 25359773.
      View in: PubMed
    114. Halder SK, Laknaur A, Miller J, Layman LC, Diamond M, Al-Hendy A. Novel MED12 gene somatic mutations in women from the Southern United States with symptomatic uterine fibroids. Mol Genet Genomics. 2015 Apr; 290(2):505-11. PMID: 25325994.
      View in: PubMed
    115. Moghazy D, Sharan C, Nair M, Rackauskas C, Burnette R, Diamond M, Al-Hendy O, Al-Hendy A. Sertoli-Leydig cell tumor with unique nail findings in a post-menopausal woman: a case report and literature review. J Ovarian Res. 2014 Aug 28; 7:83. PMID: 25296983.
      View in: PubMed
    116. Stilley JA, Christensen DE, Dahlem KB, Guan R, Santillan DA, England SK, Al-Hendy A, Kirby PA, Segaloff DL. FSH receptor (FSHR) expression in human extragonadal reproductive tissues and the developing placenta, and the impact of its deletion on pregnancy in mice. Biol Reprod. 2014 Sep; 91(3):74. PMID: 25100706.
      View in: PubMed
    117. Al-Hendy A, Badr M. Can vitamin D reduce the risk of uterine fibroids? Womens Health (Lond). 2014 Jul; 10(4):353-8. PMID: 25259897.
      View in: PubMed
    118. Zhang D, Rajaratnam V, Al-Hendy O, Halder S, Al-Hendy A. Green tea extract inhibition of human leiomyoma cell proliferation is mediated via catechol-O-methyltransferase. Gynecol Obstet Invest. 2014; 78(2):109-18. PMID: 24942317.
      View in: PubMed
    119. Halder SK, Sharan C, Al-Hendy O, Al-Hendy A. Paricalcitol, a vitamin d receptor activator, inhibits tumor formation in a murine model of uterine fibroids. Reprod Sci. 2014 Sep; 21(9):1108-19. PMID: 24925855.
      View in: PubMed
    120. Moghazy D, Al-Hendy O, Al-Hendy A. Krukenberg tumor presenting as back pain and a positive urine pregnancy test: a case report and literature review. J Ovarian Res. 2014 Apr 07; 7:36. PMID: 24708577.
      View in: PubMed
    121. Fletcher NM, Saed MG, Abuanzeh S, Abu-Soud HM, Al-Hendy A, Diamond MP, Saed GM. Nicotinamide adenine dinucleotide phosphate oxidase is differentially regulated in normal myometrium versus leiomyoma. Reprod Sci. 2014 Sep; 21(9):1145-52. PMID: 24520084.
      View in: PubMed
    122. Mohamed SA, Thota C, Browne PC, Diamond MP, Al-Hendy A. Why is Preterm Birth Stubbornly Higher in African-Americans? Obstet Gynecol Int J. 2014; 1(3). PMID: 25905109.
      View in: PubMed
    123. Halder SK, Osteen KG, Al-Hendy A. 1,25-dihydroxyvitamin d3 reduces extracellular matrix-associated protein expression in human uterine fibroid cells. Biol Reprod. 2013 Dec; 89(6):150. PMID: 24174578.
      View in: PubMed
    124. Thota C, Laknaur A, Farmer T, Ladson G, Al-Hendy A, Ismail N. Vitamin D regulates contractile profile in human uterine myometrial cells via NF-?B pathway. Am J Obstet Gynecol. 2014 Apr; 210(4):347.e1-347.e10. PMID: 24262718.
      View in: PubMed
    125. Nair S, Nguyen H, Salama S, Al-Hendy A. Obesity and the Endometrium: Adipocyte-Secreted Proinflammatory TNF a Cytokine Enhances the Proliferation of Human Endometrial Glandular Cells. Obstet Gynecol Int. 2013; 2013:368543. PMID: 24288542.
      View in: PubMed
    126. Catherino WH, Eltoukhi HM, Al-Hendy A. Racial and ethnic differences in the pathogenesis and clinical manifestations of uterine leiomyoma. Semin Reprod Med. 2013 Sep; 31(5):370-9. PMID: 23934698.
      View in: PubMed
    127. Roshdy E, Rajaratnam V, Maitra S, Sabry M, Allah AS, Al-Hendy A. Treatment of symptomatic uterine fibroids with green tea extract: a pilot randomized controlled clinical study. Int J Womens Health. 2013; 5:477-86. PMID: 23950663.
      View in: PubMed
    128. Nair S, Saed GM, Atta HM, Rajaratnam V, Diamond MP, Curiel DT, Al-Hendy A. Towards gene therapy of postoperative adhesions: fiber and transcriptional modifications enhance adenovirus targeting towards human adhesion cells. Gynecol Obstet Invest. 2013; 76(2):119-24. PMID: 23920223.
      View in: PubMed
    129. Nair S, Curiel DT, Rajaratnam V, Thota C, Al-Hendy A. Targeting adenoviral vectors for enhanced gene therapy of uterine leiomyomas. Hum Reprod. 2013 Sep; 28(9):2398-406. PMID: 23820419.
      View in: PubMed
    130. Fletcher NM, Saed MG, Abu-Soud HM, Al-Hendy A, Diamond MP, Saed GM. Uterine fibroids are characterized by an impaired antioxidant cellular system: potential role of hypoxia in the pathophysiology of uterine fibroids. J Assist Reprod Genet. 2013 Jul; 30(7):969-74. PMID: 23812845.
      View in: PubMed
    131. Halder SK, Osteen KG, Al-Hendy A. Vitamin D3 inhibits expression and activities of matrix metalloproteinase-2 and -9 in human uterine fibroid cells. Hum Reprod. 2013 Sep; 28(9):2407-16. PMID: 23814095.
      View in: PubMed
    132. Thota C, Menon R, Fortunato SJ, Brou L, Lee JE, Al-Hendy A. 1,25-Dihydroxyvitamin D deficiency is associated with preterm birth in African American and Caucasian women. Reprod Sci. 2014 Feb; 21(2):244-50. PMID: 23793474.
      View in: PubMed
    133. Ravella K, Al-Hendy A, Sharan C, Hale AB, Channon KM, Srinivasan S, Gangula PR. Chronic estrogen deficiency causes gastroparesis by altering neuronal nitric oxide synthase function. Dig Dis Sci. 2013 Jun; 58(6):1507-15. PMID: 23504347.
      View in: PubMed
    134. Sabry M, Halder SK, Allah AS, Roshdy E, Rajaratnam V, Al-Hendy A. Serum vitamin D3 level inversely correlates with uterine fibroid volume in different ethnic groups: a cross-sectional observational study. Int J Womens Health. 2013; 5:93-100. PMID: 23467803.
      View in: PubMed
    135. Gangula PR, Dong YL, Al-Hendy A, Richard-Davis G, Montgomery-Rice V, Haddad G, Millis R, Nicholas SB, Moseberry D. Protective cardiovascular and renal actions of vitamin D and estrogen. Front Biosci (Schol Ed). 2013 Jan 01; 5:134-48. PMID: 23277041.
      View in: PubMed
    136. Thota C, Farmer T, Garfield RE, Menon R, Al-Hendy A. Vitamin D elicits anti-inflammatory response, inhibits contractile-associated proteins, and modulates Toll-like receptors in human myometrial cells. Reprod Sci. 2013 Apr; 20(4):463-75. PMID: 23012315.
      View in: PubMed
    137. Peggs KJ, Nguyen H, Enayat D, Keller NR, Al-Hendy A, Raj SR. Gynecologic disorders and menstrual cycle lightheadedness in postural tachycardia syndrome. Int J Gynaecol Obstet. 2012 Sep; 118(3):242-6. PMID: 22721633.
      View in: PubMed
    138. Sabry M, Ait Allah AS, Roshdy E, Al-Hendy A. Laparoscopic management of a large torted ovarian cyst in an adolescent virgin: a case report. Int J Womens Health. 2012; 4:223-5. PMID: 22675267.
      View in: PubMed
    139. Halder SK, Sharan C, Al-Hendy A. 1,25-dihydroxyvitamin D3 treatment shrinks uterine leiomyoma tumors in the Eker rat model. Biol Reprod. 2012 Apr; 86(4):116. PMID: 22302692.
      View in: PubMed
    140. Vargis E, Brown N, Williams K, Al-Hendy A, Paria BC, Reese J, Mahadevan-Jansen A. Detecting biochemical changes in the rodent cervix during pregnancy using Raman spectroscopy. Ann Biomed Eng. 2012 Aug; 40(8):1814-24. PMID: 22411265.
      View in: PubMed
    141. Ghadami M, El-Demerdash E, Zhang D, Salama SA, Binhazim AA, Archibong AE, Chen X, Ballard BR, Sairam MR, Al-Hendy A. Bone marrow transplantation restores follicular maturation and steroid hormones production in a mouse model for primary ovarian failure. PLoS One. 2012; 7(3):e32462. PMID: 22412875.
      View in: PubMed
    142. Sabry M, Al-Hendy A. Medical treatment of uterine leiomyoma. Reprod Sci. 2012 Apr; 19(4):339-53. PMID: 22378865.
      View in: PubMed
    143. Sabry M, Al-Hendy A. Innovative oral treatments of uterine leiomyoma. Obstet Gynecol Int. 2012; 2012:943635. PMID: 22518167.
      View in: PubMed
    144. Nair S, Al-Hendy A, Tamboli RA, Marks-Shulman PA, Abumrad NN. Increased COMT expression in PCOS biology. Mol Cell Endocrinol. 2012 May 15; 355(1):188-9. PMID: 22342814.
      View in: PubMed
    145. Thota C, Menon R, Wentz MJ, Fortunato SJ, Bartlett J, Drobek CO, Nair S, Al-Hendy A. A single-nucleotide polymorphism in the fetal catechol-O-methyltransferase gene is associated with spontaneous preterm birth in African Americans. Reprod Sci. 2012 Feb; 19(2):135-42. PMID: 22158829.
      View in: PubMed
    146. Nair S, Al-Hendy A. Adipocytes enhance the proliferation of human leiomyoma cells via TNF-a proinflammatory cytokine. Reprod Sci. 2011 Dec; 18(12):1186-92. PMID: 22096007.
      View in: PubMed
    147. Hassan MH, Fouad H, Bahashwan S, Al-Hendy A. Towards non-surgical therapy for uterine fibroids: catechol-O-methyl transferase inhibitor shrinks uterine fibroid lesions in the Eker rat model. Hum Reprod. 2011 Nov; 26(11):3008-18. PMID: 21896544.
      View in: PubMed
    148. Halder SK, Goodwin JS, Al-Hendy A. 1,25-Dihydroxyvitamin D3 reduces TGF-beta3-induced fibrosis-related gene expression in human uterine leiomyoma cells. J Clin Endocrinol Metab. 2011 Apr; 96(4):E754-62. PMID: 21289245.
      View in: PubMed
    149. Sharan C, Halder SK, Thota C, Jaleel T, Nair S, Al-Hendy A. Vitamin D inhibits proliferation of human uterine leiomyoma cells via catechol-O-methyltransferase. Fertil Steril. 2011 Jan; 95(1):247-53. PMID: 20736132.
      View in: PubMed
    150. Ghadami M, El-Demerdash E, Salama SA, Binhazim AA, Archibong AE, Chen X, Ballard BR, Sairam MR, Al-Hendy A. Toward gene therapy of premature ovarian failure: intraovarian injection of adenovirus expressing human FSH receptor restores folliculogenesis in FSHR(-/-) FORKO mice. Mol Hum Reprod. 2010 Apr; 16(4):241-50. PMID: 20086006.
      View in: PubMed
    151. Zhang D, Al-Hendy M, Richard-Davis G, Montgomery-Rice V, Sharan C, Rajaratnam V, Khurana A, Al-Hendy A. Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice. Am J Obstet Gynecol. 2010 Mar; 202(3):289.e1-9. PMID: 20074693.
      View in: PubMed
    152. Zhang D, Al-Hendy M, Richard-Davis G, Montgomery-Rice V, Rajaratnam V, Al-Hendy A. Antiproliferative and proapoptotic effects of epigallocatechin gallate on human leiomyoma cells. Fertil Steril. 2010 Oct; 94(5):1887-93. PMID: 19819432.
      View in: PubMed
    153. Harirah H, Thota C, Wentz MJ, Zaman W, Al-Hendy A. Elevated expression of catechol-O-methyltransferase is associated with labor and increased prostaglandin E(2) production by human fetal membranes. Am J Obstet Gynecol. 2009 Nov; 201(5):496.e1-7. PMID: 19664748.
      View in: PubMed
    154. Atta HM, Al-Hendy A, El-Rehany MA, Dewerchin M, Abdel Raheim SR, Abdel Ghany H, Fouad R. Adenovirus-mediated overexpression of human tissue plasminogen activator prevents peritoneal adhesion formation/reformation in rats. Surgery. 2009 Jul; 146(1):12-7. PMID: 19541005.
      View in: PubMed
    155. Atta HM, Al-Hendy A, Salama SA, Shaker OG, Hammam OA. Low-dose simultaneous delivery of adenovirus encoding hepatocyte growth factor and vascular endothelial growth factor in dogs enhances liver proliferation without systemic growth factor elevation. Liver Int. 2009 Aug; 29(7):1022-30. PMID: 19515220.
      View in: PubMed
    156. Hassan MH, Othman EE, Hornung D, Al-Hendy A. Gene therapy of benign gynecological diseases. Adv Drug Deliv Rev. 2009 Aug 10; 61(10):822-35. PMID: 19446586.
      View in: PubMed
    157. Hassan M, Zhang D, Salama S, Hamada F, Arafa H, Fouad H, Walker C, Al-Hendy A. Towards fibroid gene therapy: adenovirus-mediated delivery of herpes simplex virus 1 thymidine kinase gene/ganciclovir shrinks uterine leiomyoma in the Eker rat model. Gynecol Obstet Invest. 2009; 68(1):19-32. PMID: 19325244.
      View in: PubMed
    158. Hassan MH, Salama SA, Zhang D, Arafa HM, Hamada FM, Fouad H, Walker CC, Al-Hendy A. Gene therapy targeting leiomyoma: adenovirus-mediated delivery of dominant-negative estrogen receptor gene shrinks uterine tumors in Eker rat model. Fertil Steril. 2010 Jan; 93(1):239-50. PMID: 19144333.
      View in: PubMed
    159. Salama SA, Kamel M, Awad M, Nasser AH, Al-Hendy A, Botting S, Arrastia C. Catecholestrogens induce oxidative stress and malignant transformation in human endometrial glandular cells: protective effect of catechol-O-methyltransferase. Int J Cancer. 2008 Sep 15; 123(6):1246-54. PMID: 18566989.
      View in: PubMed
    160. Othman EE, Zhu ZB, Curiel DT, Khatoon N, Salem HT, Khalifa EA, Al-Hendy A. Toward gene therapy of endometriosis: transductional and transcriptional targeting of adenoviral vectors to endometriosis cells. Am J Obstet Gynecol. 2008 Aug; 199(2):117.e1-6. PMID: 18674655.
      View in: PubMed
    161. Othman Eel-D, Hornung D, Al-Hendy A. Biomarkers of endometriosis. Expert Opin Med Diagn. 2008 Jul; 2(7):741-52. PMID: 23495814.
      View in: PubMed
    162. Heo MY, Salama SA, Khatoon N, Al-Hendy A, Au WW. Abrogation of estrogen receptor signaling augments cytotoxicity of anticancer drugs on CaSki cervical cancer cells. Anticancer Res. 2008 Jul-Aug; 28(4B):2181-7. PMID: 18751393.
      View in: PubMed
    163. Xu X, Othman Eel-D, Issaq HJ, Hornung D, Al-Hendy A, Veenstra TD. Multiplexed quantitation of endogenous estrogens and estrogen metabolites in human peritoneal fluid. Electrophoresis. 2008 Jun; 29(12):2706-13. PMID: 18512681.
      View in: PubMed
    164. Hassan MH, Eyzaguirre E, Arafa HM, Hamada FM, Salama SA, Al-Hendy A. Memy I: a novel murine model for uterine leiomyoma using adenovirus-enhanced human fibroid explants in severe combined immune deficiency mice. Am J Obstet Gynecol. 2008 Aug; 199(2):156.e1-8. PMID: 18468574.
      View in: PubMed
    165. Othman EE, Al-Hendy A. Molecular genetics and racial disparities of uterine leiomyomas. Best Pract Res Clin Obstet Gynaecol. 2008 Aug; 22(4):589-601. PMID: 18373954.
      View in: PubMed
    166. Azab SS, Salama SA, Hassan MH, Khalifa AE, El-Demerdash E, Fouad H, Al-Hendy A, Abdel-Naim AB. 2-Methoxyestradiol reverses doxorubicin resistance in human breast tumor xenograft. Cancer Chemother Pharmacol. 2008 Oct; 62(5):893-902. PMID: 18253735.
      View in: PubMed
    167. Azab SS, Salama SA, Abdel-Naim AB, Khalifa AE, El-Demerdash E, Al-Hendy A. 2-Methoxyestradiol and multidrug resistance: can 2-methoxyestradiol chemosensitize resistant breast cancer cells? Breast Cancer Res Treat. 2009 Jan; 113(1):9-19. PMID: 18228136.
      View in: PubMed
    168. Hassan MH, Khatoon N, Curiel DT, Hamada FM, Arafa HM, Al-Hendy A. Toward gene therapy of uterine fibroids: targeting modified adenovirus to human leiomyoma cells. Hum Reprod. 2008 Mar; 23(3):514-24. PMID: 18184643.
      View in: PubMed
    169. Zhang D, Fouad H, Zoma WD, Salama SA, Wentz MJ, Al-Hendy A. Expression of stem and germ cell markers within nonfollicle structures in adult mouse ovary. Reprod Sci. 2008 Feb; 15(2):139-46. PMID: 18089589.
      View in: PubMed
    170. Salih SM, Salama SA, Jamaluddin M, Fadl AA, Blok LJ, Burger CW, Nagamani M, Al-Hendy A. Progesterone-mediated regulation of catechol-O-methyl transferase expression in endometrial cancer cells. Reprod Sci. 2008 Feb; 15(2):210-20. PMID: 18089588.
      View in: PubMed
    171. Ghadami M, Salama SA, Khatoon N, Chilvers R, Nagamani M, Chedrese PJ, Al-Hendy A. Toward gene therapy of primary ovarian failure: adenovirus expressing human FSH receptor corrects the Finnish C566T mutation. Mol Hum Reprod. 2008 Jan; 14(1):9-15. PMID: 18084009.
      View in: PubMed
    172. Wentz MJ, Shi SQ, Shi L, Salama SA, Harirah HM, Fouad H, Garfield RE, Al-Hendy A. Treatment with an inhibitor of catechol-O-methyltransferase activity reduces preterm birth and impedes cervical resistance to stretch in pregnant rats. Reproduction. 2007 Dec; 134(6):831-9. PMID: 18042640.
      View in: PubMed
    173. Hassan MH, Salama SA, Arafa HM, Hamada FM, Al-Hendy A. Adenovirus-mediated delivery of a dominant-negative estrogen receptor gene in uterine leiomyoma cells abrogates estrogen- and progesterone-regulated gene expression. J Clin Endocrinol Metab. 2007 Oct; 92(10):3949-57. PMID: 17635941.
      View in: PubMed
    174. Saed GM, Al-Hendy A, Salama SA, Diamond MP. Adenovirus-mediated expression of cyclooxygenase-2 antisense reverse abnormal genetic profile of human adhesion fibroblasts. Fertil Steril. 2008 May; 89(5 Suppl):1455-60. PMID: 17624339.
      View in: PubMed
    175. Salih SM, Jamaluddin M, Salama SA, Fadl AA, Nagamani M, Al-Hendy A. Regulation of catechol O-methyltransferase expression in granulosa cells: a potential role for follicular arrest in polycystic ovary syndrome. Fertil Steril. 2008 May; 89(5 Suppl):1414-21. PMID: 17612537.
      View in: PubMed
    176. Salama SA, Jamaluddin M, Kumar R, Hassan MH, Al-Hendy A. Progesterone regulates catechol-O-methyl transferase gene expression in breast cancer cells: distinct effect of progesterone receptor isoforms. J Steroid Biochem Mol Biol. 2007 Nov-Dec; 107(3-5):253-61. PMID: 17689241.
      View in: PubMed
    177. Othman Eel-D, Hornung D, Salem HT, Khalifa EA, El-Metwally TH, Al-Hendy A. Serum cytokines as biomarkers for nonsurgical prediction of endometriosis. Eur J Obstet Gynecol Reprod Biol. 2008 Apr; 137(2):240-6. PMID: 17582674.
      View in: PubMed
    178. Salih S, Xu X, Veenstra TD, Duleba AJ, Fouad H, Nagamani M, Al-Hendy A. Lower levels of urinary 2-hydroxyestrogens in polycystic ovary syndrome. J Clin Endocrinol Metab. 2007 Aug; 92(8):3285-91. PMID: 17535988.
      View in: PubMed
    179. Salih SM, Salama SA, Fadl AA, Nagamani M, Al-Hendy A. Expression and cyclic variations of catechol-O-methyl transferase in human endometrial stroma. Fertil Steril. 2008 Sep; 90(3):789-97. PMID: 17418156.
      View in: PubMed
    180. Lu F, Longo M, Tamayo E, Maner W, Al-Hendy A, Anderson GD, Hankins GD, Saade GR. The effect of over-expression of sFlt-1 on blood pressure and the occurrence of other manifestations of preeclampsia in unrestrained conscious pregnant mice. Am J Obstet Gynecol. 2007 Apr; 196(4):396.e1-7; discussion 396.e7. PMID: 17403433.
      View in: PubMed
    181. Othman EE, Salama S, Ismail N, Al-Hendy A. Toward gene therapy of endometriosis: adenovirus-mediated delivery of dominant negative estrogen receptor genes inhibits cell proliferation, reduces cytokine production, and induces apoptosis of endometriotic cells. Fertil Steril. 2007 Aug; 88(2):462-71. PMID: 17343855.
      View in: PubMed
    182. Au WW, Abdou-Salama S, Sierra-Torres CH, Al-Hendy A. Environmental risk factors for prevention and molecular intervention of cervical cancer. Int J Hyg Environ Health. 2007 Dec; 210(6):671-678. PMID: 17157560.
      View in: PubMed
    183. Wentz MJ, Jamaluddin M, Garfield RE, Al-Hendy A. Regulation of catechol-O-methyltransferase expression in human myometrial cells. Obstet Gynecol. 2006 Dec; 108(6):1439-47. PMID: 17138778.
      View in: PubMed
    184. Au WW, Abdou-Salama S, Al-Hendy A. Inhibition of growth of cervical cancer cells using a dominant negative estrogen receptor gene. Gynecol Oncol. 2007 Feb; 104(2):276-80. PMID: 17137618.
      View in: PubMed
    185. Salama SA, Nasr AB, Dubey RK, Al-Hendy A. Estrogen metabolite 2-methoxyestradiol induces apoptosis and inhibits cell proliferation and collagen production in rat and human leiomyoma cells: a potential medicinal treatment for uterine fibroids. J Soc Gynecol Investig. 2006 Dec; 13(8):542-50. PMID: 17088081.
      View in: PubMed
    186. Salama SA, Kamel M, Christman G, Wang HQ, Fouad HM, Al-Hendy A. Gene therapy of uterine leiomyoma: adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir treatment inhibits growth of human and rat leiomyoma cells in vitro and in a nude mouse model. Gynecol Obstet Invest. 2007; 63(2):61-70. PMID: 16954695.
      View in: PubMed
    187. Al-Hendy A, Salama SA. Ethnic distribution of estrogen receptor-alpha polymorphism is associated with a higher prevalence of uterine leiomyomas in black Americans. Fertil Steril. 2006 Sep; 86(3):686-93. PMID: 16860797.
      View in: PubMed
    188. Salama SA, Ho SL, Wang HQ, Tenhunen J, Tilgmann C, Al-Hendy A. Hormonal regulation of catechol-O-methyl transferase activity in women with uterine leiomyomas. Fertil Steril. 2006 Jul; 86(1):259-62. PMID: 16730007.
      View in: PubMed
    189. Al-Hendy A, Salama S. Gene therapy and uterine leiomyoma: a review. Hum Reprod Update. 2006 Jul-Aug; 12(4):385-400. PMID: 16603566.
      View in: PubMed
    190. Al-Hendy A, Salama SA. Catechol-O-methyltransferase polymorphism is associated with increased uterine leiomyoma risk in different ethnic groups. J Soc Gynecol Investig. 2006 Feb; 13(2):136-44. PMID: 16443508.
      View in: PubMed
    191. Al-Hendy A, Lee EJ, Wang HQ, Copland JA. Gene therapy of uterine leiomyomas: adenovirus-mediated expression of dominant negative estrogen receptor inhibits tumor growth in nude mice. Am J Obstet Gynecol. 2004 Nov; 191(5):1621-31. PMID: 15547533.
      View in: PubMed
    192. Young SL, Al-Hendy A, Copland JA. Potential nonhormonal therapeutics for medical treatment of leiomyomas. Semin Reprod Med. 2004 May; 22(2):121-30. PMID: 15164307.
      View in: PubMed
    193. Al-Hendy A, Moshynska O, Saxena A, Feyles V. Association between mutations of the follicle-stimulating-hormone receptor and repeated twinning. Lancet. 2000 Sep 09; 356(9233):914. PMID: 11036902.
      View in: PubMed
    194. Al-Hendy A, Magliocco AM, Al-Tweigeri T, Braileanu G, Crellin N, Li H, Strong T, Curiel D, Chedrese PJ. Ovarian cancer gene therapy: repeated treatment with thymidine kinase in an adenovirus vector and ganciclovir improves survival in a novel immunocompetent murine model. Am J Obstet Gynecol. 2000 Mar; 182(3):553-9. PMID: 10739507.
      View in: PubMed
    195. Al-Hendy A. Enriching research culture in residency. Am J Obstet Gynecol. 1999 Nov; 181(5 Pt 1):1271. PMID: 10561660.
      View in: PubMed
    196. Al-Hendy A, Auersperg N. Applying the herpes simplex virus thymidine kinase/ganciclovir approach to ovarian cancer: an effective in vitro drug-sensitization system. Gynecol Obstet Invest. 1997; 43(4):268-75. PMID: 9194627.
      View in: PubMed
    197. Hortelano G, Al-Hendy A, Ofosu FA, Chang PL. Delivery of human factor IX in mice by encapsulated recombinant myoblasts: a novel approach towards allogeneic gene therapy of hemophilia B. Blood. 1996 Jun 15; 87(12):5095-103. PMID: 8652822.
      View in: PubMed
    198. Al-Hendy A, Hortelano G, Tannenbaum GS, Chang PL. Growth retardation--an unexpected outcome from growth hormone gene therapy in normal mice with microencapsulated myoblasts. Hum Gene Ther. 1996 Jan; 7(1):61-70. PMID: 8825869.
      View in: PubMed
    199. Skurnik M, Venho R, Toivanen P, al-Hendy A. A novel locus of Yersinia enterocolitica serotype O:3 involved in lipopolysaccharide outer core biosynthesis. Mol Microbiol. 1995 Aug; 17(3):575-94. PMID: 8559076.
      View in: PubMed
    200. al-Hendy A, Hortelano G, Tannenbaum GS, Chang PL. Correction of the growth defect in dwarf mice with nonautologous microencapsulated myoblasts--an alternate approach to somatic gene therapy. Hum Gene Ther. 1995 Feb; 6(2):165-75. PMID: 7734517.
      View in: PubMed
    201. Zhang L, al-Hendy A, Toivanen P, Skurnik M. Genetic organization and sequence of the rfb gene cluster of Yersinia enterocolitica serotype O:3: similarities to the dTDP-L-rhamnose biosynthesis pathway of Salmonella and to the bacterial polysaccharide transport systems. Mol Microbiol. 1993 Jul; 9(2):309-21. PMID: 7692217.
      View in: PubMed
    202. al-Hendy A, Toivanen P, Skurnik M. Lipopolysaccharide O side chain of Yersinia enterocolitica O:3 is an essential virulence factor in an orally infected murine model. Infect Immun. 1992 Mar; 60(3):870-5. PMID: 1311707.
      View in: PubMed
    203. al-Hendy A, Toivanen P, Skurnik M. Expression cloning of Yersinia enterocolitica O:3 rfb gene cluster in Escherichia coli K12. Microb Pathog. 1991 Jan; 10(1):47-59. PMID: 1857198.
      View in: PubMed
    204. al-Hendy A, Toivanen P, Skurnik M. Molecular cloning of Yersinia enterocolitica O:3 rfb region: evidence that temperature regulates the rfb region at the transcriptional level. Contrib Microbiol Immunol. 1991; 12:203-9. PMID: 1935091.
      View in: PubMed
    205. al-Hendy A, Toivanen P, Skurnik M. The effect of growth temperature on the biosynthesis of Yersinia enterocolitica O:3 lipopolysaccharide: temperature regulates the transcription of the rfb but not of the rfa region. Microb Pathog. 1991 Jan; 10(1):81-6. PMID: 1857201.
      View in: PubMed
    206. al-Hendy A, Toivanen P, Skurnik M. Rapid method for isolation and staining of bacterial lipopolysaccharide. Microbiol Immunol. 1991; 35(4):331-3. PMID: 1719357.
      View in: PubMed
    Al-Hendy's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _