 Synapses
"Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
| Descriptor ID |
D013569
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| MeSH Number(s) |
A08.850 A11.284.149.165.420.780
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Synapses".
Below are MeSH descriptors whose meaning is more specific than "Synapses".
This graph shows the total number of publications written about "Synapses" by people in this website by year, and whether "Synapses" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1980 | 1 | 3 | 4 | | 1982 | 1 | 0 | 1 | | 1984 | 1 | 0 | 1 | | 1985 | 2 | 1 | 3 | | 1986 | 1 | 1 | 2 | | 1987 | 5 | 2 | 7 | | 1988 | 2 | 3 | 5 | | 1989 | 1 | 2 | 3 | | 1990 | 5 | 2 | 7 | | 1991 | 3 | 1 | 4 | | 1992 | 0 | 2 | 2 | | 1993 | 4 | 2 | 6 | | 1994 | 3 | 0 | 3 | | 1995 | 1 | 2 | 3 | | 1996 | 5 | 3 | 8 | | 1997 | 5 | 1 | 6 | | 1998 | 2 | 1 | 3 | | 1999 | 2 | 0 | 2 | | 2000 | 3 | 6 | 9 | | 2001 | 6 | 3 | 9 | | 2002 | 8 | 4 | 12 | | 2003 | 12 | 3 | 15 | | 2004 | 3 | 2 | 5 | | 2005 | 3 | 2 | 5 | | 2006 | 8 | 6 | 14 | | 2007 | 6 | 5 | 11 | | 2008 | 3 | 5 | 8 | | 2009 | 7 | 8 | 15 | | 2010 | 6 | 8 | 14 | | 2011 | 7 | 5 | 12 | | 2012 | 6 | 1 | 7 | | 2013 | 7 | 5 | 12 | | 2014 | 8 | 4 | 12 | | 2015 | 4 | 4 | 8 | | 2016 | 1 | 4 | 5 | | 2017 | 2 | 5 | 7 | | 2018 | 0 | 4 | 4 | | 2019 | 4 | 1 | 5 | | 2020 | 3 | 2 | 5 | | 2021 | 2 | 3 | 5 |
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Below are the most recent publications written about "Synapses" by people in Profiles.
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González-Garrido A, Pujol R, López-Ramírez O, Finkbeiner C, Eatock RA, Stone JS. The Differentiation Status of Hair Cells That Regenerate Naturally in the Vestibular Inner Ear of the Adult Mouse. J Neurosci. 2021 09 15; 41(37):7779-7796.
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Kumar A, Basak S, Chakrapani S. Recombinant expression and purification of pentameric ligand-gated ion channels for Cryo-EM structural studies. Methods Enzymol. 2021; 652:81-103.
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Aponte DA, Handy G, Kline AM, Tsukano H, Doiron B, Kato HK. Recurrent network dynamics shape direction selectivity in primary auditory cortex. Nat Commun. 2021 01 12; 12(1):314.
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Sampathkumar V, Miller-Hansen A, Murray Sherman S, Kasthuri N. An ultrastructural connectomic analysis of a higher-order thalamocortical circuit in the mouse. Eur J Neurosci. 2021 02; 53(3):750-762.
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Wang Y, Lobb-Rabe M, Ashley J, Anand V, Carrillo RA. Structural and Functional Synaptic Plasticity Induced by Convergent Synapse Loss in the Drosophila Neuromuscular Circuit. J Neurosci. 2021 02 17; 41(7):1401-1417.
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Hansel C, Disterhoft JF. Why is synaptic plasticity not enough? Neurobiol Learn Mem. 2020 12; 176:107336.
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Abbott LF, Bock DD, Callaway EM, Denk W, Dulac C, Fairhall AL, Fiete I, Harris KM, Helmstaedter M, Jain V, Kasthuri N, LeCun Y, Lichtman JW, Littlewood PB, Luo L, Maunsell JHR, Reid RC, Rosen BR, Rubin GM, Sejnowski TJ, Seung HS, Svoboda K, Tank DW, Tsao D, Van Essen DC. The Mind of a Mouse. Cell. 2020 09 17; 182(6):1372-1376.
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Meng JL, Wang Y, Carrillo RA, Heckscher ES. Temporal transcription factors determine circuit membership by permanently altering motor neuron-to-muscle synaptic partnerships. Elife. 2020 05 11; 9.
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Li J, Xie Y, Cornelius S, Jiang X, Sando R, Kordon SP, Pan M, Leon K, Südhof TC, Zhao M, Araç D. Alternative splicing controls teneurin-latrophilin interaction and synapse specificity by a shape-shifting mechanism. Nat Commun. 2020 05 01; 11(1):2140.
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Kim KX, Atencio CA, Schreiner CE. Stimulus dependent transformations between synaptic and spiking receptive fields in auditory cortex. Nat Commun. 2020 02 27; 11(1):1102.
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