 Synapses
"Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
| Descriptor ID |
D013569
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| MeSH Number(s) |
A08.850 A11.284.149.165.420.780
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Synapses".
Below are MeSH descriptors whose meaning is more specific than "Synapses".
This graph shows the total number of publications written about "Synapses" by people in this website by year, and whether "Synapses" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1980 | 1 | 3 | 4 | | 1982 | 2 | 0 | 2 | | 1984 | 2 | 0 | 2 | | 1985 | 2 | 1 | 3 | | 1986 | 1 | 1 | 2 | | 1987 | 5 | 2 | 7 | | 1988 | 2 | 3 | 5 | | 1989 | 2 | 2 | 4 | | 1990 | 5 | 2 | 7 | | 1991 | 3 | 1 | 4 | | 1992 | 0 | 2 | 2 | | 1993 | 4 | 2 | 6 | | 1994 | 3 | 0 | 3 | | 1995 | 1 | 2 | 3 | | 1996 | 5 | 3 | 8 | | 1997 | 5 | 1 | 6 | | 1998 | 2 | 1 | 3 | | 1999 | 2 | 0 | 2 | | 2000 | 3 | 6 | 9 | | 2001 | 6 | 2 | 8 | | 2002 | 8 | 4 | 12 | | 2003 | 13 | 2 | 15 | | 2004 | 4 | 2 | 6 | | 2005 | 3 | 1 | 4 | | 2006 | 9 | 6 | 15 | | 2007 | 7 | 5 | 12 | | 2008 | 4 | 5 | 9 | | 2009 | 8 | 8 | 16 | | 2010 | 5 | 8 | 13 | | 2011 | 7 | 6 | 13 | | 2012 | 5 | 1 | 6 | | 2013 | 6 | 5 | 11 | | 2014 | 10 | 4 | 14 | | 2015 | 5 | 4 | 9 | | 2016 | 3 | 4 | 7 | | 2017 | 2 | 5 | 7 | | 2018 | 1 | 3 | 4 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Synapses" by people in Profiles.
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Huang X, Rangel M, Briggman KL, Wei W. Neural mechanisms of contextual modulation in the retinal direction selective circuit. Nat Commun. 2019 06 03; 10(1):2431.
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Wei W. Neural Mechanisms of Motion Processing in the Mammalian Retina. Annu Rev Vis Sci. 2018 09 15; 4:165-192.
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Wolfman SL, Gill DF, Bogdanic F, Long K, Al-Hasani R, McCall JG, Bruchas MR, McGehee DS. Nicotine aversion is mediated by GABAergic interpeduncular nucleus inputs to laterodorsal tegmentum. Nat Commun. 2018 07 13; 9(1):2710.
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Fassio A, Esposito A, Kato M, Saitsu H, Mei D, Marini C, Conti V, Nakashima M, Okamoto N, Olmez Turker A, Albuz B, Semerci Gündüz CN, Yanagihara K, Belmonte E, Maragliano L, Ramsey K, Balak C, Siniard A, Narayanan V. De novo mutations of the ATP6V1A gene cause developmental encephalopathy with epilepsy. Brain. 2018 06 01; 141(6):1703-1718.
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Li J, Shalev-Benami M, Sando R, Jiang X, Kibrom A, Wang J, Leon K, Katanski C, Nazarko O, Lu YC, Südhof TC, Skiniotis G, Araç D. Structural Basis for Teneurin Function in Circuit-Wiring: A Toxin Motif at the Synapse. Cell. 2018 04 19; 173(3):735-748.e15.
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Wang J, Breen D, Akinin A, Broccard F, Abarbanel HDI, Cauwenberghs G. Assimilation of Biophysical Neuronal Dynamics in Neuromorphic VLSI. IEEE Trans Biomed Circuits Syst. 2017 12; 11(6):1258-1270.
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Ma Q, Ruan H, Peng L, Zhang M, Gack MU, Yao WD. Proteasome-independent polyubiquitin linkage regulates synapse scaffolding, efficacy, and plasticity. Proc Natl Acad Sci U S A. 2017 10 10; 114(41):E8760-E8769.
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Forrest MP, Zhang H, Moy W, McGowan H, Leites C, Dionisio LE, Xu Z, Shi J, Sanders AR, Greenleaf WJ, Cowan CA, Pang ZP, Gejman PV, Penzes P, Duan J. Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci. Cell Stem Cell. 2017 09 07; 21(3):305-318.e8.
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Koren D, Grove JCR, Wei W. Cross-compartmental Modulation of Dendritic Signals for Retinal Direction Selectivity. Neuron. 2017 Aug 16; 95(4):914-927.e4.
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Lee SH, Jin C, Cai E, Ge P, Ishitsuka Y, Teng KW, de Thomaz AA, Nall D, Baday M, Jeyifous O, Demonte D, Dundas CM, Park S, Delgado JY, Green WN, Selvin PR. Super-resolution imaging of synaptic and Extra-synaptic AMPA receptors with different-sized fluorescent probes. Elife. 2017 07 27; 6.
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