"Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
| Descriptor ID |
D013569
|
| MeSH Number(s) |
A08.850 A11.284.149.165.420.780
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Synapses".
Below are MeSH descriptors whose meaning is more specific than "Synapses".
This graph shows the total number of publications written about "Synapses" by people in this website by year, and whether "Synapses" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 1 | 2 |
| 1994 | 2 | 0 | 2 |
| 1995 | 1 | 2 | 3 |
| 1996 | 5 | 3 | 8 |
| 1997 | 3 | 1 | 4 |
| 1998 | 2 | 1 | 3 |
| 1999 | 2 | 0 | 2 |
| 2000 | 2 | 6 | 8 |
| 2001 | 3 | 3 | 6 |
| 2002 | 7 | 4 | 11 |
| 2003 | 12 | 2 | 14 |
| 2004 | 2 | 1 | 3 |
| 2005 | 2 | 2 | 4 |
| 2006 | 8 | 6 | 14 |
| 2007 | 4 | 2 | 6 |
| 2008 | 3 | 4 | 7 |
| 2009 | 7 | 6 | 13 |
| 2010 | 5 | 8 | 13 |
| 2011 | 7 | 6 | 13 |
| 2012 | 5 | 1 | 6 |
| 2013 | 4 | 4 | 8 |
| 2014 | 8 | 4 | 12 |
| 2015 | 6 | 2 | 8 |
| 2016 | 3 | 4 | 7 |
| 2017 | 1 | 4 | 5 |
| 2018 | 1 | 4 | 5 |
| 2019 | 5 | 1 | 6 |
| 2020 | 3 | 2 | 5 |
| 2021 | 6 | 5 | 11 |
| 2022 | 0 | 4 | 4 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Synapses" by people in Profiles.
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Nonquantal transmission at the vestibular hair cell-calyx synapse: KLV currents modulate fast electrical and slow K+ potentials. Proc Natl Acad Sci U S A. 2023 01 10; 120(2):e2207466120.
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Large-Scale Algorithmic Search Identifies Stiff and Sloppy Dimensions in Synaptic Architectures Consistent With Murine Neocortical Wiring. Neural Comput. 2022 11 08; 34(12):2347-2373.
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Loss of function of OTUD7A in the schizophrenia- associated 15q13.3 deletion impairs synapse development and function in human neurons. Am J Hum Genet. 2022 08 04; 109(8):1500-1519.
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Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry. J Immunother Cancer. 2022 07; 10(7).
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Systematic expression profiling of Dpr and DIP genes reveals cell surface codes in Drosophila larval motor and sensory neurons. Development. 2022 05 15; 149(10).
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Stoney vs. Histed: Quantifying the spatial effects of intracortical microstimulation. Brain Stimul. 2022 Jan-Feb; 15(1):141-151.
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Nanoscale organization of Nicastrin, the substrate receptor of the ?-secretase complex, as independent molecular domains. Mol Brain. 2021 10 13; 14(1):158.
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Primate neuronal connections are sparse in cortex as compared to mouse. Cell Rep. 2021 09 14; 36(11):109709.
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Integration of signals from different cortical areas in higher order thalamic neurons. Proc Natl Acad Sci U S A. 2021 07 27; 118(30).
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The Differentiation Status of Hair Cells That Regenerate Naturally in the Vestibular Inner Ear of the Adult Mouse. J Neurosci. 2021 09 15; 41(37):7779-7796.