"Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
| Descriptor ID |
D013569
|
| MeSH Number(s) |
A08.850 A11.284.149.165.420.780
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Synapses".
Below are MeSH descriptors whose meaning is more specific than "Synapses".
This graph shows the total number of publications written about "Synapses" by people in this website by year, and whether "Synapses" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 2 | 3 |
| 1996 | 4 | 3 | 7 |
| 1997 | 3 | 1 | 4 |
| 1998 | 2 | 1 | 3 |
| 1999 | 1 | 0 | 1 |
| 2000 | 2 | 2 | 4 |
| 2001 | 2 | 1 | 3 |
| 2002 | 4 | 4 | 8 |
| 2003 | 8 | 1 | 9 |
| 2004 | 1 | 1 | 2 |
| 2005 | 2 | 2 | 4 |
| 2006 | 6 | 6 | 12 |
| 2007 | 4 | 2 | 6 |
| 2008 | 3 | 3 | 6 |
| 2009 | 7 | 5 | 12 |
| 2010 | 5 | 7 | 12 |
| 2011 | 7 | 6 | 13 |
| 2012 | 5 | 1 | 6 |
| 2013 | 4 | 4 | 8 |
| 2014 | 10 | 4 | 14 |
| 2015 | 7 | 2 | 9 |
| 2016 | 3 | 5 | 8 |
| 2017 | 2 | 3 | 5 |
| 2018 | 1 | 4 | 5 |
| 2019 | 6 | 1 | 7 |
| 2020 | 3 | 5 | 8 |
| 2021 | 6 | 5 | 11 |
| 2022 | 1 | 5 | 6 |
| 2023 | 3 | 5 | 8 |
| 2024 | 4 | 3 | 7 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Synapses" by people in Profiles.
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Targeting C1q prevents microglia-mediated synaptic removal in neuropathic pain. Nat Commun. 2025 May 17; 16(1):4590.
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Polygenic risk for alcohol use disorder affects cellular responses to ethanol exposure in a human microglial cell model. Sci Adv. 2024 Nov 08; 10(45):eado5820.
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Dietary regulation of silent synapses in the dorsolateral striatum. Neuroscience. 2024 Dec 17; 563:43-50.
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Synaptic integration of somatosensory and motor cortical inputs onto spiny projection neurons of mice caudoputamen. Eur J Neurosci. 2024 Oct; 60(8):6107-6122.
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Short-term plasticity and context-dependent circuit function: Insights from retinal circuitry. Sci Adv. 2024 Sep 20; 10(38):eadp5229.
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UNC-30/PITX coordinates neurotransmitter identity with postsynaptic GABA receptor clustering. Development. 2024 Aug 15; 151(16).
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Intrinsic and synaptic determinants of receptive field plasticity in Purkinje cells of the mouse cerebellum. Nat Commun. 2024 May 31; 15(1):4645.
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The logic of recurrent circuits in the primary visual cortex. Nat Neurosci. 2024 Jan; 27(1):137-147.
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Isochronic development of cortical synapses in primates and mice. Nat Commun. 2023 12 04; 14(1):8018.
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Excess phosphoserine-129 a-synuclein induces synaptic vesicle trafficking and declustering defects at a vertebrate synapse. Mol Biol Cell. 2024 Jan 01; 35(1):ar10.