"Adherens Junctions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Anchoring points where the CYTOSKELETON of neighboring cells are connected to each other. They are composed of specialized areas of the plasma membrane where bundles of the ACTIN CYTOSKELETON attach to the membrane through the transmembrane linkers, CADHERINS, which in turn attach through their extracellular domains to cadherins in the neighboring cell membranes. In sheets of cells, they form into adhesion belts (zonula adherens) that go all the way around a cell.
| Descriptor ID |
D022005
|
| MeSH Number(s) |
A11.284.149.165.420.020
|
| Concept/Terms |
Adherens Junctions- Adherens Junctions
- Adherens Junction
- Junction, Adherens
- Junctions, Adherens
|
Below are MeSH descriptors whose meaning is more general than "Adherens Junctions".
Below are MeSH descriptors whose meaning is more specific than "Adherens Junctions".
This graph shows the total number of publications written about "Adherens Junctions" by people in this website by year, and whether "Adherens Junctions" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 3 | 3 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 3 | 4 |
| 2016 | 0 | 1 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Adherens Junctions" by people in Profiles.
-
Force-dependent intercellular adhesion strengthening underlies asymmetric adherens junction contraction. Curr Biol. 2022 05 09; 32(9):1986-2000.e5.
-
Insights image for "Circulating extracellular vesicles from patients with acute chest syndrome disrupt adherens junctions between endothelial cells". Pediatr Res. 2021 03; 89(4):1036.
-
Circulating extracellular vesicles from patients with acute chest syndrome disrupt adherens junctions between endothelial cells. Pediatr Res. 2021 03; 89(4):776-784.
-
Phospholipase D2 restores endothelial barrier function by promoting PTPN14-mediated VE-cadherin dephosphorylation. J Biol Chem. 2020 05 29; 295(22):7669-7685.
-
RhoA Mediates Epithelial Cell Shape Changes via Mechanosensitive Endocytosis. Dev Cell. 2020 01 27; 52(2):152-166.e5.
-
Differential Expression of a Classic Cadherin Directs Tissue-Level Contractile Asymmetry during Neural Tube Closure. Dev Cell. 2019 10 21; 51(2):158-172.e4.
-
Activation of Vascular Endothelial Growth Factor (VEGF) Receptor 2 Mediates Endothelial Permeability Caused by Cyclic Stretch. J Biol Chem. 2016 May 06; 291(19):10032-45.
-
Interaction of p190RhoGAP with C-terminal domain of p120-catenin modulates endothelial cytoskeleton and permeability. J Biol Chem. 2013 Jun 21; 288(25):18290-9.
-
Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion. PLoS One. 2012; 7(11):e47842.
-
VE-cadherin trans-interactions modulate Rac activation and enhancement of lung endothelial barrier by iloprost. J Cell Physiol. 2012 Oct; 227(10):3405-16.