 Cortical Spreading Depression
"Cortical Spreading Depression" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The decrease in neuronal activity (related to a decrease in metabolic demand) extending from the site of cortical stimulation. It is believed to be responsible for the decrease in cerebral blood flow that accompanies the aura of MIGRAINE WITH AURA. (Campbell's Psychiatric Dictionary, 8th ed.)
| Descriptor ID |
D013181
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| MeSH Number(s) |
G11.561.270.300
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| Concept/Terms |
Cortical Spreading Depression- Cortical Spreading Depression
- Cortical Spreading Depressions
- Depression, Cortical Spreading
- Depressions, Cortical Spreading
- Spreading Depression, Cortical
- Spreading Depressions, Cortical
- Spreading Depression of Leao
- Leao Spreading Depression
- Cortical Depression, Spreading
- Cortical Depressions, Spreading
- Depression, Spreading Cortical
- Depressions, Spreading Cortical
- Spreading Cortical Depressions
- Spreading Cortical Depression
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Below are MeSH descriptors whose meaning is more general than "Cortical Spreading Depression".
Below are MeSH descriptors whose meaning is more specific than "Cortical Spreading Depression".
This graph shows the total number of publications written about "Cortical Spreading Depression" by people in this website by year, and whether "Cortical Spreading Depression" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 0 | 1 | 1 | | 1987 | 1 | 0 | 1 | | 1991 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1996 | 2 | 0 | 2 | | 1998 | 2 | 0 | 2 | | 2003 | 1 | 0 | 1 | | 2004 | 2 | 0 | 2 | | 2005 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cortical Spreading Depression" by people in Profiles.
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Bertels Z, Singh H, Dripps I, Siegersma K, Tipton AF, Witkowski WD, Sheets Z, Shah P, Conway C, Mangutov E, Ao M, Petukhova V, Karumudi B, Petukhov PA, Baca SM, Rasenick MM, Pradhan AA. Neuronal complexity is attenuated in preclinical models of migraine and restored by HDAC6 inhibition. Elife. 2021 04 15; 10.
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Grinberg YY, Zitzow LA, Kraig RP. Intranasally administered IGF-1 inhibits spreading depression in vivo. Brain Res. 2017 Dec 15; 1677:47-57.
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Kupferschmidt DA, Lovinger DM. Inhibition of presynaptic calcium transients in cortical inputs to the dorsolateral striatum by metabotropic GABA(B) and mGlu2/3 receptors. J Physiol. 2015 May 15; 593(10):2295-310.
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Pusic AD, Mitchell HM, Kunkler PE, Klauer N, Kraig RP. Spreading depression transiently disrupts myelin via interferon-gamma signaling. Exp Neurol. 2015 Feb; 264:43-54.
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Grinberg YY, Dibbern ME, Levasseur VA, Kraig RP. Insulin-like growth factor-1 abrogates microglial oxidative stress and TNF-a responses to spreading depression. J Neurochem. 2013 Sep; 126(5):662-72.
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Kunkler PE, Hulse RE, Schmitt MW, Nicholson C, Kraig RP. Optical current source density analysis in hippocampal organotypic culture shows that spreading depression occurs with uniquely reversing currents. J Neurosci. 2005 Apr 13; 25(15):3952-61.
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Kunkler PE, Hulse RE, Kraig RP. Multiplexed cytokine protein expression profiles from spreading depression in hippocampal organotypic cultures. J Cereb Blood Flow Metab. 2004 Aug; 24(8):829-39.
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Kunkler PE, Kraig RP. P/Q Ca2+ channel blockade stops spreading depression and related pyramidal neuronal Ca2+ rise in hippocampal organ culture. Hippocampus. 2004; 14(3):356-67.
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Kunkler PE, Kraig RP. Hippocampal spreading depression bilaterally activates the caudal trigeminal nucleus in rodents. Hippocampus. 2003; 13(7):835-44.
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Kreisman NR, Soliman S, Gozal D. Regional differences in hypoxic depolarization and swelling in hippocampal slices. J Neurophysiol. 2000 Feb; 83(2):1031-8.
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