"Astrocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.
| Descriptor ID |
D001253
|
| MeSH Number(s) |
A08.637.200 A11.650.200
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Astrocytes".
Below are MeSH descriptors whose meaning is more specific than "Astrocytes".
This graph shows the total number of publications written about "Astrocytes" by people in this website by year, and whether "Astrocytes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 3 | 5 |
| 1997 | 4 | 1 | 5 |
| 1998 | 4 | 1 | 5 |
| 1999 | 1 | 1 | 2 |
| 2000 | 1 | 5 | 6 |
| 2001 | 3 | 0 | 3 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 2 | 3 | 5 |
| 2006 | 2 | 3 | 5 |
| 2007 | 1 | 2 | 3 |
| 2008 | 3 | 0 | 3 |
| 2009 | 0 | 3 | 3 |
| 2010 | 0 | 3 | 3 |
| 2011 | 3 | 2 | 5 |
| 2012 | 3 | 1 | 4 |
| 2013 | 1 | 1 | 2 |
| 2014 | 3 | 1 | 4 |
| 2015 | 0 | 3 | 3 |
| 2016 | 3 | 1 | 4 |
| 2017 | 2 | 1 | 3 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 3 | 4 |
| 2021 | 1 | 3 | 4 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
| 2024 | 1 | 1 | 2 |
| 2025 | 1 | 3 | 4 |
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click here.
Below are the most recent publications written about "Astrocytes" by people in Profiles.
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Ethanol induces neuroimmune dysregulation and soluble TREM2 generation in a human iPSC neuron, astrocyte, microglia triculture model. Alcohol. 2026 Feb; 130:57-72.
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PICALM Alzheimer's risk allele causes aberrant lipid droplets in microglia. Nature. 2025 Oct; 646(8087):1178-1186.
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Alzheimer's disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication. Mol Neurodegener. 2025 May 03; 20(1):51.
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Variable transduction of thyroid hormone signaling in structures of the mouse brain. Proc Natl Acad Sci U S A. 2025 Feb 11; 122(6):e2415970122.
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The Musashi-1-type 2 deiodinase pathway regulates astrocyte proliferation. J Biol Chem. 2024 07; 300(7):107477.
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Metabolic trade-offs in Neonatal sepsis triggered by TLR4 and TLR1/2 ligands result in unique dysfunctions in neural breathing circuits. Brain Behav Immun. 2024 Jul; 119:333-350.
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Purinergic signaling mediates neuroglial interactions to modulate sighs. Nat Commun. 2023 08 31; 14(1):5300.
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The gut microbiome regulates astrocyte reaction to Aß amyloidosis through microglial dependent and independent mechanisms. Mol Neurodegener. 2023 Jul 06; 18(1):45.
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Astrocyte Elevated Gene-1 Cys75 S-Palmitoylation by ZDHHC6 Regulates Its Biological Activity. Biochemistry. 2023 01 17; 62(2):543-553.
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Elimination of Radiation-Induced Senescence in the Brain Tumor Microenvironment Attenuates Glioblastoma Recurrence. Cancer Res. 2021 12 01; 81(23):5935-5947.