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Harinder Singh

TitlePROFESSOR
InstitutionUniversity of Chicago
DepartmentComm: Developmental Biology
AddressChicago IL 60637
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    R01AR083713     (KAPLAN, DANIEL H)Jul 20, 2024 - Jun 30, 2029
    NIH
    Intrinsic and Extrinsic factors regulating competition for active TGFb promote skin memory CD8 T cell fitness
    Role: Co-Principal Investigator
    U01AI179514     (SINGH, HARINDER)Apr 1, 2024 - Feb 28, 2029
    NIH
    B and Tfh cell dynamics underlying durable antibody responses to flu vaccine in children
    Role: Principal Investigator
    U01EY034711     (ST LEGER, ANTHONY J)Sep 30, 2022 - Aug 31, 2027
    NIH
    Assessing how ocular surface nerves, immune cells, and epithelial cells communicate to encourage neuro-immune homeostasis
    Role: Co-Principal Investigator
    R01AI170108     (ALCORN, JOHN F)Jul 13, 2022 - Jun 30, 2027
    NIH
    Uncovering latent factors underlying weak and robust responses to influenza vaccine in healthy and obese older adults
    Role: Co-Principal Investigator
    U01HG012041     (SINGH, HARINDER)Aug 19, 2021 - May 31, 2026
    NIH
    Linking genome variation to transcriptional network dynamics in human B cells
    Role: Principal Investigator
    U01AI141990     (ELLEBEDY, ALI HASSAN)Dec 18, 2018 - Dec 31, 2028
    NIH
    Programming Durable Immune Responses To Vaccination
    Role: Co-Principal Investigator
    R01GM086213     (KERPPOLA, TOM)Sep 30, 2008 - Jul 31, 2014
    NIH
    Optimization of Bimolecular Fluorescence Complementation Probes for New Imaging F
    Role: Co-Principal Investigator
    T32GM007183     (GLICK, BENJAMIN S)Jul 1, 1975 - Jun 30, 2022
    NIH
    Molecular and Cellular Biology Training
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Reiman D, Manakkat Vijay GK, Xu H, Sonin A, Chen D, Salomonis N, Singh H, Khan AA. Pseudocell Tracer-A method for inferring dynamic trajectories using scRNAseq and its application to B cells undergoing immunoglobulin class switch recombination. PLoS Comput Biol. 2021 05; 17(5):e1008094. PMID: 33939691; PMCID: PMC8118552.
      Citations: 4     Fields:    Translation:AnimalsCells
    2. Bertels Z, Singh H, Dripps I, Siegersma K, Tipton AF, Witkowski WD, Sheets Z, Shah P, Conway C, Mangutov E, Ao M, Petukhova V, Karumudi B, Petukhov PA, Baca SM, Rasenick MM, Pradhan AA. Neuronal complexity is attenuated in preclinical models of migraine and restored by HDAC6 inhibition. Elife. 2021 04 15; 10. PMID: 33856345; PMCID: PMC8147088.
      Citations: 13     Fields:    Translation:AnimalsCells
    3. Singh H, Chmura J, Bhaumik R, Pandey GN, Rasenick MM. Membrane-Associated a-Tubulin Is Less Acetylated in Postmortem Prefrontal Cortex from Depressed Subjects Relative to Controls: Cytoskeletal Dynamics, HDAC6, and Depression. J Neurosci. 2020 05 13; 40(20):4033-4041. PMID: 32284336; PMCID: PMC7219287.
      Citations: 8     Fields:    Translation:HumansCells
    4. Sural-Fehr T, Singh H, Cantuti-Catelvetri L, Zhu H, Marshall MS, Rebiai R, Jastrzebski MJ, Givogri MI, Rasenick MM, Bongarzone ER. Inhibition of the IGF-1-PI3K-Akt-mTORC2 pathway in lipid rafts increases neuronal vulnerability in a genetic lysosomal glycosphingolipidosis. Dis Model Mech. 2019 05 23; 12(5). PMID: 31036560; PMCID: PMC6550048.
      Citations: 18     Fields:    Translation:AnimalsCells
    5. Singh H, Wray N, Schappi JM, Rasenick MM. Correction: Disruption of lipid-raft localized Gas/tubulin complexes by antidepressants: a unique feature of HDAC6 inhibitors, SSRI, and tricyclic compounds. Neuropsychopharmacology. 2019 04; 44(5):1008. PMID: 30617260; PMCID: PMC6461926.
      Citations: 1     Fields:    
    6. Karki S, Kennedy DE, Mclean K, Grzybowski AT, Maienschein-Cline M, Banerjee S, Xu H, Davis E, Mandal M, Labno C, Powers SE, Le Beau MM, Dinner AR, Singh H, Ruthenburg AJ, Clark MR. Regulated Capture of V? Gene Topologically Associating Domains by Transcription Factories. Cell Rep. 2018 08 28; 24(9):2443-2456. PMID: 30157436; PMCID: PMC6310487.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    7. Wray NH, Schappi JM, Singh H, Senese NB, Rasenick MM. NMDAR-independent, cAMP-dependent antidepressant actions of ketamine. Mol Psychiatry. 2019 12; 24(12):1833-1843. PMID: 29895894; PMCID: PMC8011999.
      Citations: 65     Fields:    Translation:HumansCells
    8. Singh H, Wray N, Schappi JM, Rasenick MM. Disruption of lipid-raft localized Gas/tubulin complexes by antidepressants: a unique feature of HDAC6 inhibitors, SSRI and tricyclic compounds. Neuropsychopharmacology. 2018 06; 43(7):1481-1491. PMID: 29463911; PMCID: PMC5983546.
      Citations: 16     Fields:    Translation:AnimalsCells
    9. Franchi L, Monteleone I, Hao LY, Spahr MA, Zhao W, Liu X, Demock K, Kulkarni A, Lesch CA, Sanchez B, Carter L, Marafini I, Hu X, Mashadova O, Yuan M, Asara JM, Singh H, Lyssiotis CA, Monteleone G, Opipari AW, Glick GD. Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis. J Immunol. 2017 04 01; 198(7):2735-2746. PMID: 28242647; PMCID: PMC5360504.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    10. Olsson A, Venkatasubramanian M, Chaudhri VK, Aronow BJ, Salomonis N, Singh H, Grimes HL. Single-cell analysis of mixed-lineage states leading to a binary cell fate choice. Nature. 2016 09 29; 537(7622):698-702. PMID: 27580035; PMCID: PMC5161694.
      Citations: 267     Fields:    Translation:AnimalsCells
    11. Xu H, Chaudhri VK, Wu Z, Biliouris K, Dienger-Stambaugh K, Rochman Y, Singh H. Regulation of bifurcating B cell trajectories by mutual antagonism between transcription factors IRF4 and IRF8. Nat Immunol. 2015 Dec; 16(12):1274-81. PMID: 26437243.
      Citations: 68     Fields:    Translation:AnimalsCells
    12. Singh H. Transcriptional and epigenetic networks orchestrating immune cell development and function. Immunol Rev. 2014 Sep; 261(1):5-8. PMID: 25123273.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    13. Singh H, Khan AA, Dinner AR. Gene regulatory networks in the immune system. Trends Immunol. 2014 May; 35(5):211-8. PMID: 24768519.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    14. Singh H, Glasmacher E, Chang AB, Vander Lugt B. The molecular choreography of IRF4 and IRF8 with immune system partners. Cold Spring Harb Symp Quant Biol. 2013; 78:101-4. PMID: 24752218.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    15. Clark MR, Mandal M, Ochiai K, Singh H. Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signalling. Nat Rev Immunol. 2014 Feb; 14(2):69-80. PMID: 24378843; PMCID: PMC4276135.
      Citations: 155     Fields:    Translation:HumansAnimalsCells
    16. Vander Lugt B, Khan AA, Hackney JA, Agrawal S, Lesch J, Zhou M, Lee WP, Park S, Xu M, DeVoss J, Spooner CJ, Chalouni C, Delamarre L, Mellman I, Singh H. Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation. Nat Immunol. 2014 Feb; 15(2):161-7. PMID: 24362890.
      Citations: 134     Fields:    Translation:AnimalsCells
    17. Spooner CJ, Lesch J, Yan D, Khan AA, Abbas A, Ramirez-Carrozzi V, Zhou M, Soriano R, Eastham-Anderson J, Diehl L, Lee WP, Modrusan Z, Pappu R, Xu M, DeVoss J, Singh H. Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1. Nat Immunol. 2013 Dec; 14(12):1229-36. PMID: 24141388.
      Citations: 90     Fields:    Translation:AnimalsCells
    18. Ochiai K, Maienschein-Cline M, Simonetti G, Chen J, Rosenthal R, Brink R, Chong AS, Klein U, Dinner AR, Singh H, Sciammas R. Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4. Immunity. 2013 May 23; 38(5):918-29. PMID: 23684984; PMCID: PMC3690549.
      Citations: 220     Fields:    Translation:AnimalsCells
    19. Singh H, Ansari HR, Raghava GP. Improved method for linear B-cell epitope prediction using antigen's primary sequence. PLoS One. 2013; 8(5):e62216. PMID: 23667458; PMCID: PMC3646881.
      Citations: 140     Fields:    Translation:Cells
    20. Williams JW, Tjota MY, Clay BS, Vander Lugt B, Bandukwala HS, Hrusch CL, Decker DC, Blaine KM, Fixsen BR, Singh H, Sciammas R, Sperling AI. Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation. Nat Commun. 2013; 4:2990. PMID: 24356538; PMCID: PMC4003872.
      Citations: 199     Fields:    Translation:AnimalsCells
    21. Tussiwand R, Lee WL, Murphy TL, Mashayekhi M, KC W, Satpathy AT, Rotondo JA, Edelson BT, Kretzer NM, Wu X, Weiss LA, Glasmacher E, Li P, Liao W, Behnke M, Lam SS, Aurthur CT, Leonard WJ, Singh H, Stallings CL, Sibley LD, Schreiber RD, Murphy KM, Albring JC. Compensatory dendritic cell development mediated by BATF-IRF interactions. Nature. 2012 Oct 25; 490(7421):502-7. PMID: 22992524; PMCID: PMC3482832.
      Citations: 219     Fields:    Translation:AnimalsCells
    22. Glasmacher E, Agrawal S, Chang AB, Murphy TL, Zeng W, Vander Lugt B, Khan AA, Ciofani M, Spooner CJ, Rutz S, Hackney J, Nurieva R, Escalante CR, Ouyang W, Littman DR, Murphy KM, Singh H. A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes. Science. 2012 Nov 16; 338(6109):975-80. PMID: 22983707; PMCID: PMC5789805.
      Citations: 208     Fields:    Translation:HumansAnimalsCells
    23. Zullo JM, Demarco IA, Gaffney DJ, Epstein CB, Spooner CJ, Luperchio TR, Bernstein BE, Pritchard JK, Reddy KL, Singh H, Piqué-Regi R. DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina. Cell. 2012 Jun 22; 149(7):1474-87. PMID: 22726435.
      Citations: 248     Fields:    Translation:AnimalsCells
    24. Seiler MP, Mathew R, Liszewski MK, Spooner CJ, Spooner C, Barr K, Meng F, Singh H, Bendelac A. Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling. Nat Immunol. 2012 Feb 05; 13(3):264-71. PMID: 22306690; PMCID: PMC3288314.
      Citations: 128     Fields:    Translation:HumansAnimalsCells
    25. Ochiai K, Maienschein-Cline M, Mandal M, Triggs JR, Bertolino E, Sciammas R, Dinner AR, Clark MR, Singh H. A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation. Nat Immunol. 2012 Jan 22; 13(3):300-7. PMID: 22267219; PMCID: PMC4028049.
      Citations: 90     Fields:    Translation:AnimalsCells
    26. Becker AM, Michael DG, Satpathy AT, Sciammas R, Singh H, Bhattacharya D. IRF-8 extinguishes neutrophil production and promotes dendritic cell lineage commitment in both myeloid and lymphoid mouse progenitors. Blood. 2012 Mar 01; 119(9):2003-12. PMID: 22238324; PMCID: PMC3311244.
      Citations: 81     Fields:    Translation:HumansAnimalsCells
    27. Demarco IA, Singh H. The A-MYSM power of deubiquitinases. Immunity. 2011 Dec 23; 35(6):847-9. PMID: 22195739.
      Citations:    Fields:    
    28. Rutz S, Noubade R, Ota N, Zeng W, Zheng Y, Hackney J, Ding J, Singh H, Ouyang W, Eidenschenk C. Transcription factor c-Maf mediates the TGF-ß-dependent suppression of IL-22 production in T(H)17 cells. Nat Immunol. 2011 Oct 16; 12(12):1238-45. PMID: 22001828.
      Citations: 98     Fields:    Translation:HumansAnimalsCells
    29. Ramirez-Carrozzi V, Sambandam A, Luis E, Lin Z, Jeet S, Lesch J, Hackney J, Kim J, Zhou M, Lai J, Modrusan Z, Sai T, Lee W, Xu M, Caplazi P, Diehl L, de Voss J, Balazs M, Gonzalez L, Singh H, Ouyang W, Pappu R. IL-17C regulates the innate immune function of epithelial cells in an autocrine manner. Nat Immunol. 2011 Oct 12; 12(12):1159-66. PMID: 21993848.
      Citations: 210     Fields:    Translation:HumansAnimalsCells
    30. Singh H. Introductory perspective. Semin Immunol. 2011 Oct; 23(5):315-6. PMID: 22082671.
      Citations:    Fields:    Translation:HumansCells
    31. Sciammas R, Li Y, Warmflash A, Song Y, Dinner AR, Singh H. An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling. Mol Syst Biol. 2011 May 24; 7:495. PMID: 21613984; PMCID: PMC3130558.
      Citations: 64     Fields:    Translation:AnimalsCells
    32. Mewborn SK, Puckelwartz MJ, Abuisneineh F, Fahrenbach JP, Zhang Y, MacLeod H, Dellefave L, Pytel P, Selig S, Labno CM, Reddy K, Singh H, McNally E. Altered chromosomal positioning, compaction, and gene expression with a lamin A/C gene mutation. PLoS One. 2010 Dec 14; 5(12):e14342. PMID: 21179469; PMCID: PMC3001866.
      Citations: 64     Fields:    Translation:HumansCells
    33. Singh H, Demarco IA. Immunology. Double TIP-ping. Science. 2010 Aug 20; 329(5994):914-5. PMID: 20724627.
      Citations:    Fields:    Translation:AnimalsCells
    34. Jo SH, Schatz JH, Acquaviva J, Singh H, Ren R. Cooperation between deficiencies of IRF-4 and IRF-8 promotes both myeloid and lymphoid tumorigenesis. Blood. 2010 Oct 14; 116(15):2759-67. PMID: 20585039; PMCID: PMC2974585.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    35. Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P, Cheng JX, Murre C, Singh H, Glass CK. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell. 2010 May 28; 38(4):576-89. PMID: 20513432; PMCID: PMC2898526.
      Citations: 6571     Fields:    Translation:AnimalsCells
    36. Hu Z, Negrotto S, Gu X, Mahfouz R, Ng KP, Ebrahem Q, Copelan E, Singh H, Maciejewski JP, Saunthararajah Y. Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus. Mol Cancer Ther. 2010 Jun; 9(6):1536-43. PMID: 20501800; PMCID: PMC2884053.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    37. Aikawa Y, Katsumoto T, Zhang P, Shima H, Shino M, Terui K, Ito E, Ohno H, Stanley ER, Singh H, Tenen DG, Kitabayashi I. PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2. Nat Med. 2010 May; 16(5):580-5, 1p following 585. PMID: 20418886; PMCID: PMC3039870.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    38. Spooner CJ, Cheng JX, Pujadas E, Laslo P, Singh H. A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates. Immunity. 2009 Oct 16; 31(4):576-86. PMID: 19818654; PMCID: PMC4373467.
      Citations: 93     Fields:    Translation:AnimalsCells
    39. Mandal M, Powers SE, Ochiai K, Georgopoulos K, Kee BL, Singh H, Clark MR. Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development. Nat Immunol. 2009 Oct; 10(10):1110-7. PMID: 19734904; PMCID: PMC3057509.
      Citations: 65     Fields:    Translation:AnimalsCells
    40. Singh H. Teeing up transcription on CpG islands. Cell. 2009 Jul 10; 138(1):14-6. PMID: 19596228.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    41. Johnson K, Reddy KL, Singh H. Molecular pathways and mechanisms regulating the recombination of immunoglobulin genes during B-lymphocyte development. Adv Exp Med Biol. 2009; 650:133-47. PMID: 19731807.
      Citations: 7     Fields:    Translation:AnimalsCells
    42. Laslo P, Pongubala JM, Lancki DW, Singh H. Gene regulatory networks directing myeloid and lymphoid cell fates within the immune system. Semin Immunol. 2008 Aug; 20(4):228-35. PMID: 18771937.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    43. Singh H. PU.1, a shared transcriptional regulator of innate and adaptive immune cell fates. J Immunol. 2008 Aug 01; 181(3):1595-6. PMID: 18641293.
      Citations: 4     Fields:    Translation:AnimalsCells
    44. Reynaud D, Demarco IA, Reddy KL, Schjerven H, Bertolino E, Chen Z, Smale ST, Winandy S, Singh H. Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros. Nat Immunol. 2008 Aug; 9(8):927-36. PMID: 18568028; PMCID: PMC2699484.
      Citations: 145     Fields:    Translation:AnimalsCells
    45. Schlimgen RJ, Reddy KL, Singh H, Krangel MS. Initiation of allelic exclusion by stochastic interaction of Tcrb alleles with repressive nuclear compartments. Nat Immunol. 2008 Jul; 9(7):802-9. PMID: 18536719; PMCID: PMC2561338.
      Citations: 37     Fields:    Translation:AnimalsCells
    46. Johnson K, Hashimshony T, Sawai CM, Pongubala JM, Skok JA, Aifantis I, Singh H. Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling. Immunity. 2008 Mar; 28(3):335-45. PMID: 18280186.
      Citations: 106     Fields:    Translation:AnimalsCells
    47. Pongubala JM, Northrup DL, Lancki DW, Medina KL, Treiber T, Bertolino E, Thomas M, Grosschedl R, Allman D, Singh H. Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5. Nat Immunol. 2008 Feb; 9(2):203-15. PMID: 18176567.
      Citations: 120     Fields:    Translation:AnimalsCells
    48. Gantner BN, Singh H. Immunology: Short-term memory. Nature. 2007 Jun 21; 447(7147):916-7. PMID: 17581569.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    49. Littman DR, Singh H. Immunology. Asymmetry and immune memory. Science. 2007 Mar 23; 315(5819):1673-4. PMID: 17379796.
      Citations: 4     Fields:    Translation:AnimalsCells
    50. Singh H. Shaping a helper T cell identity. Nat Immunol. 2007 Feb; 8(2):119-20. PMID: 17242680.
      Citations: 3     Fields:    Translation:Cells
    51. Singh H, Pongubala JM, Medina KL. Gene regulatory networks that orchestrate the development of B lymphocyte precursors. Adv Exp Med Biol. 2007; 596:57-62. PMID: 17338175.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    52. Krysinska H, Hoogenkamp M, Ingram R, Wilson N, Tagoh H, Laslo P, Singh H, Bonifer C. A two-step, PU.1-dependent mechanism for developmentally regulated chromatin remodeling and transcription of the c-fms gene. Mol Cell Biol. 2007 Feb; 27(3):878-87. PMID: 17116688; PMCID: PMC1800675.
      Citations: 41     Fields:    Translation:AnimalsCells
    53. Laslo P, Spooner CJ, Warmflash A, Lancki DW, Lee HJ, Sciammas R, Gantner BN, Dinner AR, Singh H. Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. Cell. 2006 Aug 25; 126(4):755-66. PMID: 16923394.
      Citations: 301     Fields:    Translation:AnimalsCells
    54. Sciammas R, Shaffer AL, Schatz JH, Zhao H, Staudt LM, Singh H. Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation. Immunity. 2006 Aug; 25(2):225-36. PMID: 16919487.
      Citations: 282     Fields:    Translation:AnimalsCells
    55. Singh H, Sciammas R. Shedding B cell identity. Immunity. 2006 Mar; 24(3):239-40. PMID: 16546090.
      Citations:    Fields:    Translation:AnimalsCells
    56. Singh H, Pongubala JM. Gene regulatory networks and the determination of lymphoid cell fates. Curr Opin Immunol. 2006 Apr; 18(2):116-20. PMID: 16473505.
      Citations: 4     Fields:    Translation:AnimalsCells
    57. Bertolino E, Reddy K, Medina KL, Parganas E, Ihle J, Singh H. Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5. Nat Immunol. 2005 Aug; 6(8):836-43. PMID: 16025120.
      Citations: 60     Fields:    Translation:AnimalsCells
    58. Medina KL, Singh H. Genetic networks that regulate B lymphopoiesis. Curr Opin Hematol. 2005 May; 12(3):203-9. PMID: 15867576.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    59. Singh H, Medina KL, Pongubala JM. Contingent gene regulatory networks and B cell fate specification. Proc Natl Acad Sci U S A. 2005 Apr 05; 102(14):4949-53. PMID: 15788530; PMCID: PMC555998.
      Citations: 79     Fields:    Translation:HumansAnimalsCells
    60. Tamura T, Tailor P, Yamaoka K, Kong HJ, Tsujimura H, O'Shea JJ, Singh H, Ozato K. IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity. J Immunol. 2005 Mar 01; 174(5):2573-81. PMID: 15728463.
      Citations: 208     Fields:    Translation:AnimalsCells
    61. Medina KL, Pongubala JM, Reddy KL, Lancki DW, Dekoter R, Kieslinger M, Grosschedl R, Singh H. Assembling a gene regulatory network for specification of the B cell fate. Dev Cell. 2004 Oct; 7(4):607-17. PMID: 15469848.
      Citations: 93     Fields:    Translation:AnimalsCells
    62. Maier H, Ostraat R, Gao H, Fields S, Shinton SA, Medina KL, Ikawa T, Murre C, Singh H, Hardy RR, Hagman J. Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription. Nat Immunol. 2004 Oct; 5(10):1069-77. PMID: 15361869.
      Citations: 82     Fields:    Translation:AnimalsCells
    63. Dahl R, Walsh JC, Lancki D, Laslo P, Iyer SR, Singh H, Simon MC. Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor. Nat Immunol. 2003 Oct; 4(10):1029-36. PMID: 12958595.
      Citations: 162     Fields:    Translation:AnimalsCells
    64. Lu R, Medina KL, Lancki DW, Singh H. IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development. Genes Dev. 2003 Jul 15; 17(14):1703-8. PMID: 12832394; PMCID: PMC196178.
      Citations: 122     Fields:    Translation:AnimalsCells
    65. Walsh JC, DeKoter RP, Lee HJ, Smith ED, Lancki DW, Gurish MF, Friend DS, Stevens RL, Anastasi J, Singh H. Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates. Immunity. 2002 Nov; 17(5):665-76. PMID: 12433372.
      Citations: 120     Fields:    Translation:AnimalsCells
    66. Escalante CR, Brass AL, Pongubala JM, Shatova E, Shen L, Singh H, Aggarwal AK. Crystal structure of PU.1/IRF-4/DNA ternary complex. Mol Cell. 2002 Nov; 10(5):1097-105. PMID: 12453417.
      Citations: 66     Fields:    Translation:AnimalsCells
    67. Bertolino E, Singh H. POU/TBP cooperativity: a mechanism for enhancer action from a distance. Mol Cell. 2002 Aug; 10(2):397-407. PMID: 12191484.
      Citations: 27     Fields:    Translation:AnimalsCells
    68. Escalante CR, Shen L, Escalante MC, Brass AL, Edwards TA, Singh H, Aggarwal AK. Crystallization and characterization of PU.1/IRF-4/DNA ternary complex. J Struct Biol. 2002 Jul; 139(1):55-9. PMID: 12372320.
      Citations: 7     Fields:    Translation:AnimalsCells
    69. Rengarajan J, Mowen KA, McBride KD, Smith ED, Singh H, Glimcher LH. Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression. J Exp Med. 2002 Apr 15; 195(8):1003-12. PMID: 11956291; PMCID: PMC2193700.
      Citations: 144     Fields:    Translation:HumansAnimalsCells
    70. Kosak ST, Skok JA, Medina KL, Riblet R, Le Beau MM, Fisher AG, Singh H. Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development. Science. 2002 Apr 05; 296(5565):158-62. PMID: 11935030.
      Citations: 326     Fields:    Translation:AnimalsCells
    71. DeKoter RP, Lee HJ, Singh H. PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors. Immunity. 2002 Feb; 16(2):297-309. PMID: 11869689.
      Citations: 88     Fields:    Translation:HumansAnimalsCells
    72. Singh HP, Hurley RM, Myers TF. Neonatal hypertension. Incidence and risk factors. Am J Hypertens. 1992 Feb; 5(2):51-5. PMID: 1550665.
      Citations: 24     Fields:    Translation:Humans
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