"Islets of Langerhans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.
| Descriptor ID |
D007515
|
| MeSH Number(s) |
A03.734.414 A06.407.414
|
| Concept/Terms |
Islets of Langerhans- Islets of Langerhans
- Langerhans Islets
- Pancreatic Islets
- Islet, Pancreatic
- Islets, Pancreatic
- Pancreatic Islet
- Nesidioblasts
- Nesidioblast
- Pancreas, Endocrine
- Endocrine Pancreas
- Islands of Langerhans
- Langerhans Islands
- Islet Cells
- Cell, Islet
- Cells, Islet
- Islet Cell
|
Below are MeSH descriptors whose meaning is more general than "Islets of Langerhans".
Below are MeSH descriptors whose meaning is more specific than "Islets of Langerhans".
This graph shows the total number of publications written about "Islets of Langerhans" by people in this website by year, and whether "Islets of Langerhans" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 9 | 4 | 13 |
| 1994 | 11 | 3 | 14 |
| 1995 | 7 | 5 | 12 |
| 1996 | 14 | 6 | 20 |
| 1997 | 6 | 3 | 9 |
| 1998 | 15 | 3 | 18 |
| 1999 | 7 | 1 | 8 |
| 2000 | 12 | 4 | 16 |
| 2001 | 12 | 6 | 18 |
| 2002 | 11 | 3 | 14 |
| 2003 | 19 | 5 | 24 |
| 2004 | 20 | 9 | 29 |
| 2005 | 17 | 2 | 19 |
| 2006 | 9 | 5 | 14 |
| 2007 | 7 | 4 | 11 |
| 2008 | 5 | 2 | 7 |
| 2009 | 7 | 2 | 9 |
| 2010 | 9 | 1 | 10 |
| 2011 | 8 | 3 | 11 |
| 2012 | 6 | 1 | 7 |
| 2013 | 6 | 3 | 9 |
| 2014 | 9 | 3 | 12 |
| 2015 | 7 | 2 | 9 |
| 2016 | 6 | 2 | 8 |
| 2017 | 4 | 1 | 5 |
| 2018 | 8 | 2 | 10 |
| 2019 | 6 | 0 | 6 |
| 2020 | 7 | 3 | 10 |
| 2021 | 6 | 0 | 6 |
| 2022 | 2 | 0 | 2 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Islets of Langerhans" by people in Profiles.
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Palmitoylation couples insulin hypersecretion with ? cell failure in diabetes. Cell Metab. 2023 Feb 07; 35(2):332-344.e7.
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Proinflammatory signaling in islet ? cells propagates invasion of pathogenic immune cells in autoimmune diabetes. Cell Rep. 2022 06 28; 39(13):111011.
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MYCL-mediated reprogramming expands pancreatic insulin-producing cells. Nat Metab. 2022 02; 4(2):254-268.
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Pancreatic Islets Quality and Potency Cannot be Verified as Required for Drugs: Reflection on the FDA Review of a Biological License Application for Human Islets. Transplantation. 2021 12 01; 105(12):e409-e410.
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In Vivo and In Situ Approach to Study Islet Microcirculation: A Mini-Review. Front Endocrinol (Lausanne). 2021; 12:602620.
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Regulatory updates are needed to prevent the commercialization of islet transplantation in the United States. Am J Transplant. 2021 07; 21(7):2620-2622.
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Anticoagulation practices in total pancreatectomy with autologous islet cell transplant patients: an international survey of clinical programs. Transpl Int. 2021 03; 34(3):593-595.
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Neither amyloid depositions nor hepatic steatosis are associated with marginal islet mass early after autotransplantation. Am J Transplant. 2021 05; 21(5):1985-1987.
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Circulating miRNA in Patients Undergoing Total Pancreatectomy and Islet Autotransplantation. Cell Transplant. 2021 Jan-Dec; 30:963689721999330.
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Preoperative ERCP has no impact on islet yield following total pancreatectomy and islet autotransplantation (TPIAT): Results from the Prospective Observational Study of TPIAT (POST) cohort. Pancreatology. 2021 Jan; 21(1):275-281.