"Islets of Langerhans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.
| Descriptor ID |
D007515
|
| MeSH Number(s) |
A03.734.414 A06.407.414
|
| Concept/Terms |
Islets of Langerhans- Islets of Langerhans
- Langerhans Islets
- Pancreatic Islets
- Islet, Pancreatic
- Islets, Pancreatic
- Pancreatic Islet
- Nesidioblasts
- Nesidioblast
- Pancreas, Endocrine
- Endocrine Pancreas
- Islands of Langerhans
- Langerhans Islands
- Islet Cells
- Cell, Islet
- Cells, Islet
- Islet Cell
|
Below are MeSH descriptors whose meaning is more general than "Islets of Langerhans".
Below are MeSH descriptors whose meaning is more specific than "Islets of Langerhans".
This graph shows the total number of publications written about "Islets of Langerhans" by people in this website by year, and whether "Islets of Langerhans" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 7 | 5 | 12 |
| 1996 | 14 | 6 | 20 |
| 1997 | 6 | 3 | 9 |
| 1998 | 15 | 3 | 18 |
| 1999 | 7 | 1 | 8 |
| 2000 | 12 | 4 | 16 |
| 2001 | 12 | 6 | 18 |
| 2002 | 11 | 3 | 14 |
| 2003 | 19 | 5 | 24 |
| 2004 | 20 | 8 | 28 |
| 2005 | 17 | 2 | 19 |
| 2006 | 9 | 5 | 14 |
| 2007 | 7 | 3 | 10 |
| 2008 | 5 | 2 | 7 |
| 2009 | 7 | 2 | 9 |
| 2010 | 9 | 1 | 10 |
| 2011 | 8 | 2 | 10 |
| 2012 | 6 | 1 | 7 |
| 2013 | 5 | 3 | 8 |
| 2014 | 9 | 3 | 12 |
| 2015 | 7 | 2 | 9 |
| 2016 | 6 | 2 | 8 |
| 2017 | 4 | 1 | 5 |
| 2018 | 8 | 2 | 10 |
| 2019 | 6 | 0 | 6 |
| 2020 | 7 | 3 | 10 |
| 2021 | 6 | 0 | 6 |
| 2022 | 3 | 0 | 3 |
| 2023 | 5 | 0 | 5 |
| 2024 | 2 | 1 | 3 |
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Below are the most recent publications written about "Islets of Langerhans" by people in Profiles.
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Islet Isolation Outcomes in Patients Undergoing Total Pancreatectomy With Islet Autotransplantation in the POST Consortium. Transplantation. 2025 Jan 01; 109(1):207-216.
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Local Dialogues Between the Endocrine and Exocrine Cells in the Pancreas. Diabetes. 2024 04 01; 73(4):533-541.
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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. Nature. 2024 Mar; 627(8003):347-357.
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Inflammation-induced subcutaneous neovascularization for the long-term survival of encapsulated islets without immunosuppression. Nat Biomed Eng. 2024 Oct; 8(10):1266-1284.
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Geometric and topological characterization of the cytoarchitecture of islets of Langerhans. PLoS Comput Biol. 2023 Nov; 19(11):e1011617.
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Pancreatic regional blood flow links the endocrine and exocrine diseases. J Clin Invest. 2023 08 01; 133(15).
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Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. Diabetes. 2023 04 01; 72(4):433-448.
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Palmitoylation couples insulin hypersecretion with ß cell failure in diabetes. Cell Metab. 2023 02 07; 35(2):332-344.e7.
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Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. Pancreas. 2022 10 01; 51(9):1061-1073.
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Proinflammatory signaling in islet ß cells propagates invasion of pathogenic immune cells in autoimmune diabetes. Cell Rep. 2022 06 28; 39(13):111011.