Eukaryotic Initiation Factor-2
"Eukaryotic Initiation Factor-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Eukaryotic initiation factor of protein synthesis. In higher eukaryotes the factor consists of three subunits: alpha, beta, and gamma. As initiation proceeds, eIF-2 forms a ternary complex with Met-tRNAi and GTP.
|Eukaryotic Initiation Factor-2
- Eukaryotic Initiation Factor-2
- Eukaryotic Initiation Factor 2
- Initiation Factor-2, Eukaryotic
- Peptide Initiation Factor EIF-2
- Peptide Initiation Factor EIF 2
- Eukaryotic Peptide Initiation Factor-2
- Eukaryotic Peptide Initiation Factor 2
- EIF 2
Below are MeSH descriptors whose meaning is more general than "Eukaryotic Initiation Factor-2".
Below are MeSH descriptors whose meaning is more specific than "Eukaryotic Initiation Factor-2".
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Below are the most recent publications written about "Eukaryotic Initiation Factor-2" by people in Profiles.
Activation of the Integrated Stress Response and Metabolic Dysfunction in a Murine Model of Sleep Apnea. Am J Respir Cell Mol Biol. 2017 10; 57(4):477-486.
Harnessing the integrated stress response for the treatment of multiple sclerosis. Lancet Neurol. 2016 Apr; 15(4):434-43.
An enhanced integrated stress response ameliorates mutant SOD1-induced ALS. Hum Mol Genet. 2014 May 15; 23(10):2629-38.
A self-defeating anabolic program leads to ?-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux. J Biol Chem. 2013 Jun 14; 288(24):17202-13.
Genome-wide identification and quantitative analysis of cleaved tRNA fragments induced by cellular stress. J Biol Chem. 2012 Dec 14; 287(51):42708-25.
Endoplasmic reticulum stress decreases intracellular thyroid hormone activation via an eIF2a-mediated decrease in type 2 deiodinase synthesis. Mol Endocrinol. 2011 Dec; 25(12):2065-75.
Dysregulation of the unfolded protein response in db/db mice with diet-induced steatohepatitis. Hepatology. 2011 Nov; 54(5):1600-9.
Selective control of amino acid metabolism by the GCN2 eIF2 kinase pathway in Saccharomyces cerevisiae. BMC Biochem. 2010 Aug 04; 11:29.
Stress granule formation mediates the inhibition of colonic Hsp70 translation by interferon-gamma and tumor necrosis factor-alpha. Am J Physiol Gastrointest Liver Physiol. 2010 Apr; 298(4):G481-92.
Post-training dephosphorylation of eEF-2 promotes protein synthesis for memory consolidation. PLoS One. 2009 Oct 13; 4(10):e7424.