"Ion Channel Gating" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The opening and closing of ion channels due to a stimulus. The stimulus can be a change in membrane potential (voltage-gated), drugs or chemical transmitters (ligand-gated), or a mechanical deformation. Gating is thought to involve conformational changes of the ion channel which alters selective permeability.
| Descriptor ID |
D015640
|
| MeSH Number(s) |
G02.111.820.400 G04.835.400 G07.265.625
|
| Concept/Terms |
Ion Channel Gating- Ion Channel Gating
- Gating, Ion Channel
- Gatings, Ion Channel
- Ion Channel Gatings
|
Below are MeSH descriptors whose meaning is more general than "Ion Channel Gating".
Below are MeSH descriptors whose meaning is more specific than "Ion Channel Gating".
This graph shows the total number of publications written about "Ion Channel Gating" by people in this website by year, and whether "Ion Channel Gating" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 6 | 4 | 10 |
| 1995 | 2 | 5 | 7 |
| 1996 | 3 | 8 | 11 |
| 1997 | 0 | 3 | 3 |
| 1998 | 7 | 3 | 10 |
| 1999 | 4 | 7 | 11 |
| 2000 | 3 | 3 | 6 |
| 2001 | 4 | 3 | 7 |
| 2002 | 6 | 7 | 13 |
| 2003 | 2 | 3 | 5 |
| 2004 | 8 | 5 | 13 |
| 2005 | 11 | 2 | 13 |
| 2006 | 10 | 11 | 21 |
| 2007 | 8 | 2 | 10 |
| 2008 | 8 | 5 | 13 |
| 2009 | 4 | 2 | 6 |
| 2010 | 10 | 5 | 15 |
| 2011 | 9 | 2 | 11 |
| 2012 | 10 | 1 | 11 |
| 2013 | 10 | 2 | 12 |
| 2014 | 5 | 1 | 6 |
| 2015 | 5 | 2 | 7 |
| 2016 | 0 | 5 | 5 |
| 2017 | 1 | 3 | 4 |
| 2018 | 9 | 3 | 12 |
| 2019 | 3 | 0 | 3 |
| 2020 | 3 | 1 | 4 |
| 2021 | 3 | 2 | 5 |
| 2022 | 2 | 0 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ion Channel Gating" by people in Profiles.
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Potassium dependent structural changes in the selectivity filter of HERG potassium channels. Nat Commun. 2024 Aug 29; 15(1):7470.
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Mechanism of voltage gating in the voltage-sensing phosphatase Ci-VSP. Proc Natl Acad Sci U S A. 2022 11; 119(44):e2206649119.
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Mechanism of voltage sensing in Ca2+- and voltage-activated K+ (BK) channels. Proc Natl Acad Sci U S A. 2022 06 21; 119(25):e2204620119.
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Tracking the movement of discrete gating charges in a voltage-gated potassium channel. Elife. 2021 11 15; 10.
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Gating current noise produced by Brownian models of a voltage sensor. Biophys J. 2021 09 21; 120(18):3983-4001.
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Computational study of non-conductive selectivity filter conformations and C-type inactivation in a voltage-dependent potassium channel. J Gen Physiol. 2021 09 06; 153(9).
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Impaired cytoplasmic domain interactions cause co-assembly defect and loss of function in the p.Glu293Lys KNCJ2 variant isolated from an Andersen-Tawil syndrome patient. Cardiovasc Res. 2021 07 07; 117(8):1923-1934.
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Direct activation of the proton channel by albumin leads to human sperm capacitation and sustained release of inflammatory mediators by neutrophils. Nat Commun. 2021 06 22; 12(1):3855.
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Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs. Nat Commun. 2020 07 27; 11(1):3752.
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TOK channels use the two gates in classical K+ channels to achieve outward rectification. FASEB J. 2020 07; 34(7):8902-8919.