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Unrestricted C3 activation occurs in Crry-deficient kidneys and rapidly leads to chronic renal failure.

Bao L, Wang Y, Chang A, Minto AW, Zhou J, Kang H, Haas M, Quigg RJ. Unrestricted C3 activation occurs in Crry-deficient kidneys and rapidly leads to chronic renal failure. J Am Soc Nephrol. 2007 Mar; 18(3):811-22.

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