 Receptors, Antigen, T-Cell, gamma-delta
"Receptors, Antigen, T-Cell, gamma-delta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
T-cell receptors composed of CD3-associated gamma and delta polypeptide chains and expressed primarily in CD4-/CD8- T-cells. The receptors appear to be preferentially located in epithelial sites and probably play a role in the recognition of bacterial antigens. The T-cell receptor gamma/delta chains are separate and not related to the gamma and delta chains which are subunits of CD3 (see ANTIGENS, CD3).
| Descriptor ID |
D016692
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| MeSH Number(s) |
D12.776.543.750.705.816.824.830
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| Concept/Terms |
Receptors, Antigen, T-Cell, gamma-delta- Receptors, Antigen, T-Cell, gamma-delta
- Antigen Receptors, T-Cell, gamma-delta
- TcR gamma-delta
- TcR gamma delta
- gamma-delta, TcR
- T-Cell Receptor, gamma-delta
- T Cell Receptor, gamma delta
- gamma-delta T-Cell Receptor
- T-Cell Receptors, gamma-delta
- gamma-delta T-Cell Receptors
- Receptors, Antigen, T Cell, gamma delta
- T Cell Receptors, gamma delta
Antigen T Cell Receptor, gamma Chain- Antigen T Cell Receptor, gamma Chain
- T-Cell Receptors gamma-Chain
- T Cell Receptors gamma Chain
- gamma-Chain, T-Cell Receptors
- T-Cell Receptor gamma-Chain
- T Cell Receptor gamma Chain
- gamma-Chain, T-Cell Receptor
T-Cell Receptors delta-Chain- T-Cell Receptors delta-Chain
- T Cell Receptors delta Chain
- delta-Chain, T-Cell Receptors
- Antigen T Cell Receptor, delta Chain
- T-Cell Receptor delta-Chain
- T Cell Receptor delta Chain
- delta-Chain, T-Cell Receptor
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Below are MeSH descriptors whose meaning is more general than "Receptors, Antigen, T-Cell, gamma-delta".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Antigen [D12.776.543.750.705.816]
- Receptors, Antigen, T-Cell [D12.776.543.750.705.816.824]
- Receptors, Antigen, T-Cell, gamma-delta [D12.776.543.750.705.816.824.830]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Antigen, T-Cell, gamma-delta".
This graph shows the total number of publications written about "Receptors, Antigen, T-Cell, gamma-delta" by people in this website by year, and whether "Receptors, Antigen, T-Cell, gamma-delta" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1989 | 0 | 1 | 1 | | 1991 | 0 | 1 | 1 | | 1992 | 2 | 1 | 3 | | 1993 | 5 | 1 | 6 | | 1994 | 3 | 0 | 3 | | 1995 | 2 | 1 | 3 | | 1996 | 1 | 1 | 2 | | 1997 | 3 | 0 | 3 | | 1998 | 2 | 0 | 2 | | 1999 | 1 | 1 | 2 | | 2001 | 1 | 1 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 2 | 1 | 3 | | 2006 | 1 | 1 | 2 | | 2007 | 1 | 1 | 2 | | 2008 | 3 | 0 | 3 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 2 | 0 | 2 | | 2012 | 5 | 0 | 5 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 1 | 2 | | 2015 | 3 | 0 | 3 | | 2016 | 3 | 0 | 3 | | 2017 | 2 | 1 | 3 | | 2018 | 1 | 2 | 3 | | 2019 | 2 | 0 | 2 | | 2020 | 2 | 1 | 3 | | 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Receptors, Antigen, T-Cell, gamma-delta" by people in Profiles.
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Polese B, Thurairajah B, Zhang H, Soo CL, McMahon CA, Fontes G, Hussain SNA, Abadie V, King IL. Prostaglandin E2 amplifies IL-17 production by ?d T cells during barrier inflammation. Cell Rep. 2021 07 27; 36(4):109456.
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Mallis RJ, Duke-Cohan JS, Das DK, Akitsu A, Luoma AM, Banik D, Stephens HM, Tetteh PW, Castro CD, Krahnke S, Hussey RE, Lawney B, Brazin KN, Reche PA, Hwang W, Adams EJ, Lang MJ, Reinherz EL. Molecular design of the ?dT cell receptor ectodomain encodes biologically fit ligand recognition in the absence of mechanosensing. Proc Natl Acad Sci U S A. 2021 06 29; 118(26).
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Castro CD, Boughter CT, Broughton AE, Ramesh A, Adams EJ. Diversity in recognition and function of human ?d T cells. Immunol Rev. 2020 11; 298(1):134-152.
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Daniels J, Doukas PG, Escala MEM, Ringbloom KG, Shih DJH, Yang J, Tegtmeyer K, Park J, Thomas JJ, Selli ME, Altunbulakli C, Gowthaman R, Mo SH, Jothishankar B, Pease DR, Pro B, Abdulla FR, Shea C, Sahni N, Gru AA, Pierce BG, Louissaint A, Guitart J, Choi J. Cellular origins and genetic landscape of cutaneous gamma delta T cell lymphomas. Nat Commun. 2020 04 14; 11(1):1806.
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Fichtner AS, Karunakaran MM, Gu S, Boughter CT, Borowska MT, Starick L, Nöhren A, Göbel TW, Adams EJ, Herrmann T. Alpaca (Vicugna pacos), the first nonprimate species with a phosphoantigen-reactive V?9Vd2 T cell subset. Proc Natl Acad Sci U S A. 2020 03 24; 117(12):6697-6707.
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Deiss TC, Breaux B, Ott JA, Daniel RA, Chen PL, Castro CD, Ohta Y, Flajnik MF, Criscitiello MF. Ancient Use of Ig Variable Domains Contributes Significantly to the TCRd Repertoire. J Immunol. 2019 09 01; 203(5):1265-1275.
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Mayassi T, Ladell K, Gudjonson H, McLaren JE, Shaw DG, Tran MT, Rokicka JJ, Lawrence I, Grenier JC, van Unen V, Ciszewski C, Dimaano M, Sayegh HE, Kumar V, Wijmenga C, Green PHR, Gokhale R, Jericho H, Semrad CE, Guandalini S, Dinner AR, Kupfer SS, Reid HH, Barreiro LB, Rossjohn J, Price DA, Jabri B. Chronic Inflammation Permanently Reshapes Tissue-Resident Immunity in Celiac Disease. Cell. 2019 02 21; 176(5):967-981.e19.
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Benveniste PM, Roy S, Nakatsugawa M, Chen ELY, Nguyen L, Millar DG, Ohashi PS, Hirano N, Adams EJ, Zúñiga-Pflücker JC. Generation and molecular recognition of melanoma-associated antigen-specific human ?d T cells. Sci Immunol. 2018 12 14; 3(30).
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McDonald BD, Jabri B, Bendelac A. Diverse developmental pathways of intestinal intraepithelial lymphocytes. Nat Rev Immunol. 2018 08; 18(8):514-525.
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Hu MD, Ethridge AD, Lipstein R, Kumar S, Wang Y, Jabri B, Turner JR, Edelblum KL. Epithelial IL-15 Is a Critical Regulator of ?d Intraepithelial Lymphocyte Motility within the Intestinal Mucosa. J Immunol. 2018 07 15; 201(2):747-756.
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