Receptor-CD3 Complex, Antigen, T-Cell
"Receptor-CD3 Complex, Antigen, T-Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Molecule composed of the non-covalent association of the T-cell antigen receptor (RECEPTORS, ANTIGEN, T-CELL) with the CD3 complex (CD3 COMPLEX). This association is required for the surface expression and function of both components. The molecule consists of up to seven chains: either the alpha/beta or gamma/delta chains of the T-cell receptor, and four or five chains in the CD3 complex.
| Descriptor ID |
D017260
|
| MeSH Number(s) |
D12.776.543.750.705.816.824.800 D23.050.301.264.894.095.800 D23.101.100.894.095.800
|
| Concept/Terms |
Receptor-CD3 Complex, Antigen, T-Cell- Receptor-CD3 Complex, Antigen, T-Cell
- TCR-CD3 Complex
- Complex, TCR-CD3
- TCR CD3 Complex
- T-Cell Antigen Receptor-CD3 Complex
- T Cell Antigen Receptor CD3 Complex
|
Below are MeSH descriptors whose meaning is more general than "Receptor-CD3 Complex, Antigen, T-Cell".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Antigen [D12.776.543.750.705.816]
- Receptors, Antigen, T-Cell [D12.776.543.750.705.816.824]
- Receptor-CD3 Complex, Antigen, T-Cell [D12.776.543.750.705.816.824.800]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, Differentiation, T-Lymphocyte [D23.050.301.264.894]
- CD3 Complex [D23.050.301.264.894.095]
- Receptor-CD3 Complex, Antigen, T-Cell [D23.050.301.264.894.095.800]
- Biomarkers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, Differentiation, T-Lymphocyte [D23.101.100.894]
- CD3 Complex [D23.101.100.894.095]
- Receptor-CD3 Complex, Antigen, T-Cell [D23.101.100.894.095.800]
Below are MeSH descriptors whose meaning is more specific than "Receptor-CD3 Complex, Antigen, T-Cell".
This graph shows the total number of publications written about "Receptor-CD3 Complex, Antigen, T-Cell" by people in this website by year, and whether "Receptor-CD3 Complex, Antigen, T-Cell" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Receptor-CD3 Complex, Antigen, T-Cell" by people in Profiles.
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The CD3 conformational change in the ?d T cell receptor is not triggered by antigens but can be enforced to enhance tumor killing. Cell Rep. 2014 Jun 12; 7(5):1704-1715.
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Sensitivity of NK1.1-negative NKT cells to transgenic BATF defines a role for activator protein-1 in the expansion and maturation of immature NKT cells in the thymus. J Immunol. 2007 Jan 01; 178(1):58-66.
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The Src family kinase Fyn mediates signals induced by TCR antagonists. J Immunol. 2002 May 01; 168(9):4480-7.
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Inhibition of T-cell activation by an anti-human class I MHC reactive monoclonal antibody occurs at a point distal to TCR-CD3 mediated signal transduction. Transplant Proc. 1995 Feb; 27(1):395-7.
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Purification and characterization of a pregnancy-associated protein: TJ6s. Am J Reprod Immunol. 1995 Jan; 33(1):60-7.