Wnt-ß-catenin activation epigenetically reprograms Treg cells in inflammatory bowel disease and dysplastic progression.

Wnt-ß-catenin activation epigenetically reprograms Treg cells in inflammatory bowel disease and dysplastic progression. Nat Immunol. 2021 04; 22(4):471-484.

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subject areas

Animals
Case-Control Studies
Cell Proliferation
Cells, Cultured
Cellular Reprogramming
Colitis, Ulcerative
Crohn Disease
Cytokines
Disease Models, Animal
Epigenesis, Genetic
Forkhead Transcription Factors
Gene Expression Regulation, Neoplastic
Hepatocyte Nuclear Factor 1-alpha
Humans
Lymphocyte Activation
Mice
Mice, Inbred C57BL
Mice, Transgenic
Nuclear Receptor Subfamily 1, Group F, Member 3
Phenotype
T Cell Transcription Factor 1
T-Lymphocytes, Regulatory
Wnt Signaling Pathway

authors with profiles

Fotini Gounari
Christopher Weber
Joel R. Pekow
Randy Sweis
Alexander Pearson